Charoen, P; Nitsch, D; Engmann, J; Shah, T; White, J; Zabaneh, D; Jefferis, B; Wannamethee, G; Whincup, P; Mulick Cassidy, A; +31 more... Gaunt, T; Day, I; McLachlan, S; Price, J; Kumari, M; Kivimaki, M; Brunner, E; Langenberg, C; Ben-Shlomo, Y; Hingorani, A; Whittaker, J; Pablo Casas, J; Dudbridge, F; UCLEB Consortium; , COLLABORATORS; Dale, C; Finan, C; Wong, A; Ong, K; Drenos, F; Cooper, J; Sofat, R; Schmidt, F; Lawlor, DA; Talmud, PJ; Humphries, SE; Hardy, R; Kuh, D; Wareham, N; Morris, R; Plagno, V; (2016) Mendelian Randomisation study of the influence of eGFR on coronary heart disease. Scientific reports, 6. p. 28514. ISSN 2045-2322 DOI: https://doi.org/10.1038/srep28514

Swerdlow, DI; Kuchenbaecker, KB; Shah, S; Sofat, R; Holmes, MV; White, J; Mindell, JS; Kivimaki, M; Brunner, EJ; Whittaker, JC; +2 more... Casas, JP; Hingorani, AD; (2016) Selecting instruments for Mendelian randomization in the wake of genome-wide association studies. International journal of epidemiology. ISSN 0300-5771 DOI: https://doi.org/10.1093/ije/dyw088

Moore, GE; Ishida, M; Demetriou, C; Al-Olabi, L; Leon, LJ; Thomas, AC; Abu-Amero, S; Frost, JM; Stafford, JL; Chaoqun, Y; +12 more... Duncan, AJ; Baigel, R; Brimioulle, M; Iglesias-Platas, I; Apostolidou, S; Aggarwal, R; Whittaker, JC; Syngelaki, A; Nicolaides, KH; Regan, L; Monk, D; Stanier, P; (2015) The role and interaction of imprinted genes in human fetal growth. Philosophical transactions of the Royal Society of London Series B, Biological sciences, 370 (1663). ISSN 0962-8436 DOI: https://doi.org/10.1098/rstb.2014.0074

Nelson, MR; Tipney, H; Painter, JL; Shen, J; Nicoletti, P; Shen, Y; Floratos, A; Sham, PC; Li, MJ; Wang, J; +3 more... Cardon, LR; Whittaker, JC; Sanseau, P; (2015) The support of human genetic evidence for approved drug indications. Nature genetics, 47 (8). pp. 856-60. ISSN 1061-4036 DOI: https://doi.org/10.1038/ng.3314 Full text not available from this repository.

Nüesch, E; Dale, C; Palmer, TM; White, J; Keating, BJ; van Iperen, EP; Goel, A; Padmanabhan, S; Asselbergs, FW; EPIC-Netherland Investigators; +71 more... Verschuren, WM; Wijmenga, C; Van der Schouw, YT; Onland-Moret, NC; Lange, LA; Hovingh, GK; Sivapalaratnam, S; Morris, RW; Whincup, PH; Wannamethe, GS; Gaunt, TR; Ebrahim, S; Steel, L; Nair, N; Reiner, AP; Kooperberg, C; Wilson, JF; Bolton, JL; McLachlan, S; Price, JF; Strachan, MW; Robertson, CM; Kleber, ME; Delgado, G; März, W; Melander, O; Dominiczak, AF; Farrall, M; Watkins, H; Leusink, M; Maitland-van der Zee, AH; de Groot, MC; Dudbridge, F; Hingorani, A; Ben-Shlomo, Y; Lawlor, DA; UCLEB Investigators; Amuzu, A; Caufield, M; Cavadino, A; Cooper, J; Davies, TL; IN Day; Drenos, F; Engmann, J; Finan, C; Giambartolomei, C; Hardy, R; Humphries, SE; Hypponen, E; Kivimaki, M; Kuh, D; Kumari, M; Ong, K; Plagnol, V; Power, C; Richards, M; Shah, S; Shah, T; Sofat, R; Talmud, PJ; Wareham, N; Warren, H; Whittaker, JC; Wong, A; Zabaneh, D; Davey Smith, G; Wells, JC; Leon, DA; Holmes, MV; Casas, JP; (2015) Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis. International journal of epidemiology. ISSN 0300-5771 DOI: https://doi.org/10.1093/ije/dyv074

Xu, CF; Johnson, T; Garcia-Donas, J; Choueiri, TK; Sternberg, CN; Davis, ID; Bing, N; Deen, KC; Xue, Z; McCann, L; +6 more... Esteban, E; Whittaker, JC; Spraggs, CF; Rodríguez-Antona, C; Pandite, LN; Motzer, RJ; (2015) IL8 polymorphisms and overall survival in pazopanib- or sunitinib-treated patients with renal cell carcinoma. British journal of cancer, 112 (7). pp. 1190-8. ISSN 0007-0920 DOI: https://doi.org/10.1038/bjc.2015.64

Futema, M; Shah, S; Cooper, JA; Li, K; Whittall, RA; Sharifi, M; Goldberg, O; Drogari, E; Mollaki, V; Wiegman, A; +16 more... Defesche, J; D'Agostino, MN; D'Angelo, A; Rubba, P; Fortunato, G; Walus-Miarka, M; Hegele, RA; Aderayo Bamimore, M; Durst, R; Leitersdorf, E; Mulder, MT; Roeters van Lennep, JE; Sijbrands, EJ; Whittaker, JC; Talmud, PJ; Humphries, SE; (2014) Refinement of Variant Selection for the LDL Cholesterol Genetic Risk Score in the Diagnosis of the Polygenic Form of Clinical Familial Hypercholesterolemia and Replication in Samples from 6 Countries. Clinical chemistry. ISSN 0009-9147 DOI: https://doi.org/10.1373/clinchem.2014.231365 Full text not available from this repository.

Holmes, MV; Dale, CE; Zuccolo, L; Silverwood, RJ; Guo, Y; Ye, Z; Prieto-Merino, D; Dehghan, A; Trompet, S; Wong, A; +146 more... Cavadino, A; Drogan, D; Padmanabhan, S; Li, S; Yesupriya, A; Leusink, M; Sundstrom, J; Hubacek, JA; Pikhart, H; Swerdlow, DI; Panayiotou, AG; Borinskaya, SA; Finan, C; Shah, S; Kuchenbaecker, KB; Shah, T; Engmann, J; Folkersen, L; Eriksson, P; Ricceri, F; Melander, O; Sacerdote, C; Gamble, DM; Rayaprolu, S; Ross, OA; McLachlan, S; Vikhireva, O; Sluijs, I; Scott, RA; Adamkova, V; Flicker, L; Bockxmeer, FM; Power, C; Marques-Vidal, P; Meade, T; Marmot, MG; Ferro, JM; Paulos-Pinheiro, S; Humphries, SE; Talmud, PJ; Mateo Leach, I; Verweij, N; Linneberg, A; Skaaby, T; Doevendans, PA; Cramer, MJ; Harst, Pv; Klungel, OH; Dowling, NF; Dominiczak, AF; Kumari, M; Nicolaides, AN; Weikert, C; Boeing, H; Ebrahim, S; Gaunt, TR; Price, JF; Lannfelt, L; Peasey, A; Kubinova, R; Pajak, A; Malyutina, S; Voevoda, MI; Tamosiunas, A; Maitland-van der Zee, AH; Norman, PE; Hankey, GJ; Bergmann, MM; Hofman, A; Franco, OH; Cooper, J; Palmen, J; Spiering, W; Jong, PA; Kuh, D; Hardy, R; Uitterlinden, AG; Ikram, MA; Ford, I; Hyppönen, E; Almeida, OP; Wareham, NJ; Khaw, KT; Hamsten, A; Husemoen, LL; Tjønneland, A; Tolstrup, JS; Rimm, E; Beulens, JW; Verschuren, WM; Onland-Moret, NC; Hofker, MH; Wannamethee, SG; Whincup, PH; Morris, R; Vicente, AM; Watkins, H; Farrall, M; Jukema, JW; Meschia, J; Cupples, LA; Sharp, SJ; Fornage, M; Kooperberg, C; LaCroix, AZ; Dai, JY; Lanktree, MB; Siscovick, DS; Jorgenson, E; Spring, B; Coresh, J; Li, YR; Buxbaum, SG; Schreiner, PJ; Ellison, RC; Tsai, MY; Patel, SR; Redline, S; Johnson, AD; Hoogeveen, RC; Hakonarson, H; Rotter, JI; Boerwinkle, E; Bakker, PI; Kivimaki, M; Asselbergs, FW; Sattar, N; Lawlor, DA; Whittaker, J; Davey Smith, G; Mukamal, K; Psaty, BM; Wilson, JG; Lange, LA; Hamidovic, A; Hingorani, AD; Nordestgaard, BG; Bobak, M; Leon, DA; Langenberg, C; Palmer, TM; Reiner, AP; Keating, BJ; Dudbridge, F; Casas, JP; InterAct Consortium; (2014) Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data. BMJ (Clinical research ed), 349. g4164. ISSN 0959-8138 DOI: https://doi.org/10.1136/bmj.g4164

Silverwood, RJ; Holmes, MV; Dale, CE; Lawlor, DA; Whittaker, JC; Smith, GD; Leon, DA; Palmer, T; Keating, BJ; Zuccolo, L; +3 more... Casas, JP; Dudbridge, F; Alcohol-ADH1B Consortium; (2014) Testing for non-linear causal effects using a binary genotype in a Mendelian randomization study: application to alcohol and cardiovascular traits. International journal of epidemiology, 43 (6). pp. 1781-90. ISSN 0300-5771 DOI: https://doi.org/10.1093/ije/dyu187

Swerdlow, DI; Preiss, D; Kuchenbaecker, KB; Holmes, MV; Engmann, JE; Shah, T; Sofat, R; Stender, S; Johnson, PC; Scott, RA; +126 more... Leusink, M; Verweij, N; Sharp, SJ; Guo, Y; Giambartolomei, C; Chung, C; Peasey, A; Amuzu, A; Li, K; Palmen, J; Howard, P; Cooper, JA; Drenos, F; Li, YR; Lowe, G; Gallacher, J; Stewart, MC; Tzoulaki, I; Buxbaum, SG; van der A, DL; Forouhi, NG; Onland-Moret, NC; van der Schouw, YT; Schnabel, RB; Hubacek, JA; Kubinova, R; Baceviciene, M; Tamosiunas, A; Pajak, A; Topor-Madry, R; Stepaniak, U; Malyutina, S; Baldassarre, D; Sennblad, B; Tremoli, E; de Faire, U; Veglia, F; Ford, I; Jukema, JW; Westendorp, RG; de Borst, GJ; de Jong, PA; Algra, A; Spiering, W; Maitland-van der Zee, AH; Klungel, OH; de Boer, A; Doevendans, PA; Eaton, CB; Robinson, JG; Duggan, D; DIAGRAM Consortium; MAGIC Consortium; InterAct Consortium; Kjekshus, J; Downs, JR; Gotto, AM; Keech, AC; Marchioli, R; Tognoni, G; Sever, PS; Poulter, NR; Waters, DD; Pedersen, TR; Amarenco, P; Nakamura, H; McMurray, JJ; Lewsey, JD; Chasman, DI; Ridker, PM; Maggioni, AP; Tavazzi, L; Ray, KK; Seshasai, SR; Manson, JE; Price, JF; Whincup, PH; Morris, RW; Lawlor, DA; Smith, GD; Ben-Shlomo, Y; Schreiner, PJ; Fornage, M; Siscovick, DS; Cushman, M; Kumari, M; Wareham, NJ; Verschuren, WM; Redline, S; Patel, SR; Whittaker, JC; Hamsten, A; Delaney, JA; Dale, C; Gaunt, TR; Wong, A; Kuh, D; Hardy, R; Kathiresan, S; Castillo, BA; van der Harst, P; Brunner, EJ; Tybjaerg-Hansen, A; Marmot, MG; Krauss, RM; Tsai, M; Coresh, J; Hoogeveen, RC; Psaty, BM; Lange, LA; Hakonarson, H; Dudbridge, F; Humphries, SE; Talmud, PJ; Kivimäki, M; Timpson, NJ; Langenberg, C; Asselbergs, FW; Voevoda, M; Bobak, M; Pikhart, H; Wilson, JG; Reiner, AP; Keating, BJ; Hingorani, AD; Sattar, N; (2014) HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials. Lancet, 385 (9965). pp. 351-61. ISSN 0140-6736 DOI: https://doi.org/10.1016/S0140-6736(14)61183-1

Talmud, PJ; Cooper, JA; Morris, RW; Dudbridge, F; Shah, T; Engmann, J; Dale, C; White, J; McLachlan, S; Zabaneh, D; +21 more... Wong, A; Ong, KK; Gaunt, T; Holmes, MV; Lawlor, DA; Richards, M; Hardy, R; Kuh, D; Wareham, N; Langenberg, C; Ben-Shlomo, Y; Wannamethee, SG; Strachan, MW; Kumari, M; Whittaker, JC; Drenos, F; Kivimaki, M; Hingorani, AD; Price, JF; Humphries, SE; on behalf of the UCLEB Consortium; (2014) Sixty-five common genetic variants and prediction of type 2 diabetes. Diabetes. ISSN 0012-1797 DOI: https://doi.org/10.2337/db14-1504

Vimaleswaran, KS; Cavadino, A; Berry, DJ; LifeLines Cohort Study investigators; Jorde, R; Dieffenbach, AK; Lu, C; Alves, AC; Heerspink, HJ; Tikkanen, E; +98 more... Eriksson, J; Wong, A; Mangino, M; Jablonski, KA; Nolte, IM; Houston, DK; Ahluwalia, TS; van der Most, PJ; Pasko, D; Zgaga, L; Thiering, E; Vitart, V; Fraser, RM; Huffman, JE; de Boer, RA; Schöttker, B; Saum, KU; McCarthy, MI; Dupuis, J; Herzig, KH; Sebert, S; Pouta, A; Laitinen, J; Kleber, ME; Navis, G; Lorentzon, M; Jameson, K; Arden, N; Cooper, JA; Acharya, J; Hardy, R; Raitakari, O; Ripatti, S; Billings, LK; Lahti, J; Osmond, C; Penninx, BW; Rejnmark, L; Lohman, KK; Paternoster, L; Stolk, RP; Hernandez, DG; Byberg, L; Hagström, E; Melhus, H; Ingelsson, E; Mellström, D; Ljunggren, O; Tzoulaki, I; McLachlan, S; Theodoratou, E; Tiesler, CM; Jula, A; Navarro, P; Wright, AF; Polasek, O; International Consortium for Blood Pressure (ICBP); Cohorts for Heart and Aging Research in Genomic Epidemiology (CH; Global Blood Pressure Genetics (Global BPGen) consortium; Caroline Hayward; Wilson, JF; Rudan, I; Salomaa, V; Heinrich, J; Campbell, H; Price, JF; Karlsson, M; Lind, L; Michaëlsson, K; Bandinelli, S; Frayling, TM; Hartman, CA; Sørensen, TI; Kritchevsky, SB; Langdahl, BL; Eriksson, JG; Florez, JC; Spector, TD; Lehtimäki, T; Kuh, D; Humphries, SE; Cooper, C; Ohlsson, C; März, W; de Borst, MH; Kumari, M; Kivimaki, M; Wang, TJ; Power, C; Brenner, H; Grimnes, G; van der Harst, P; Snieder, H; Hingorani, AD; Pilz, S; Whittaker, JC; Järvelin, MR; Hyppönen, E; (2014) Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study. The lancet Diabetes & endocrinology. ISSN 2213-8587 DOI: https://doi.org/10.1016/S2213-8587(14)70113-5

Dixon, PH; Wadsworth, CA; Chambers, J; Donnelly, J; Cooley, S; Buckley, R; Mannino, R; Jarvis, S; Syngelaki, A; Geenes, V; +13 more... Paul, P; Sothinathan, M; Kubitz, R; Lammert, F; Tribe, RM; Ch'ng, CL; Marschall, HU; Glantz, A; Khan, SA; Nicolaides, K; Whittaker, J; Geary, M; Williamson, C; (2013) A Comprehensive Analysis of Common Genetic Variation Around Six Candidate Loci for Intrahepatic Cholestasis of Pregnancy. The American journal of gastroenterology, 109 (1). pp. 76-84. ISSN 0002-9270 DOI: https://doi.org/10.1038/ajg.2013.406 Full text not available from this repository.

Shah, S; Casas, JP; Drenos, F; Whittaker, J; Deanfield, J; Swerdlow, DI; Holmes, MV; Kivimaki, M; Langenberg, C; Wareham, N; +13 more... Gertow, K; Sennblad, B; Strawbridge, RJ; Baldassarre, D; Veglia, F; Tremoli, E; Gigante, B; de Faire, U; Kumari, M; Talmud, PJ; Hamsten, A; Humphries, SE; Hingorani, AD; (2013) Causal Relevance of Blood Lipid Fractions in the Development of Carotid Atherosclerosis Mendelian Randomization Analysis. Circulation Cardiovascular genetics, 6 (1). pp. 63-72. ISSN 1942-325X DOI: https://doi.org/10.1161/CIRCGENETICS.112.963140 Full text not available from this repository.

Shah, T; Zabaneh, D; Gaunt, T; Swerdlow, DI; Shah, S; Talmud, PJ; Day, IN; Whittaker, J; Holmes, MV; Sofat, R; +5 more... Humphries, SE; Kivimaki, M; Kumari, M; Hingorani, AD; Casas, JP; (2013) Gene-Centric Analysis Identifies Variants Associated With Interleukin-6 Levels and Shared Pathways With Other Inflammation Markers. Circulation Cardiovascular genetics, 6 (2). 163-+. ISSN 1942-325X DOI: https://doi.org/10.1161/CIRCGENETICS.112.964254 Full text not available from this repository.

Talmud, PJ; Shah, S; Whittall, R; Futema, M; Howard, P; Cooper, JA; Harrison, SC; LI, K; Drenos, F; Karpe, F; +9 more... Neil, HAW; Descamps, OS; Langenberg, C; Lench, N; Kivimaki, M; Whittaker, J; Hingorani, AD; Kumari, M; Humphries, SE; (2013) Use of low-density lipoprotein cholesterol gene score to distinguish patients with polygenic and monogenic familial hypercholesterolaemia: a case-control study. Lancet, 381 (9874). pp. 1293-1301. ISSN 0140-6736 DOI: https://doi.org/10.1016/S0140-6736(12)62127-8 Full text not available from this repository.

Nelson, MR; Wegmann, D; Ehm, MG; Kessner, D; St Jean, P; Verzilli, C; Shen, J; Tang, Z; Bacanu, SA; Fraser, D; +21 more... Warren, L; Aponte, J; Zawistowski, M; Liu, X; Zhang, H; Zhang, Y; Li, J; Li, Y; Li, L; Woollard, P; Topp, S; Hall, MD; Nangle, K; Wang, J; Abecasis, G; Cardon, LR; Zöllner, S; Whittaker, JC; Chissoe, SL; Novembre, J; Mooser, V; (2012) An abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people. Science (New York, NY), 337 (6090). pp. 100-4. ISSN 0036-8075 DOI: https://doi.org/10.1126/science.1217876 Full text not available from this repository.

Dixon, PH; Wadsworth, CA; Chambers, J; Donnelly, J; Cooley, SM; Jarvis, S; Kubitz, R; Lammert, F; Marschall, HU; Glantz, A; +4 more... Khan, SA; Whittaker, J; Geary, M; Williamson, C; (2010) The Role of Common Genetic Variation around Six Candidate Loci for Susceptibility to Intrahepatic Cholestasis of Pregnancy. [Conference or Workshop Item] http://researchonline.lshtm.ac.uk/id/eprint/902 Full text not available from this repository.

Morris, DL; Roberts, AL; Witherden, AS; Tarzi, R; Barros, P; Whittaker, JC; Cook, TH; Aitman, TJ; Vyse, TJ; (2010) Evidence for both copy number and allelic (NA1/NA2) risk at the FCGR3B locus in systemic lupus erythematosus. European journal of human genetics, 18 (9). pp. 1027-1031. ISSN 1018-4813 DOI: https://doi.org/10.1038/ejhg.2010.56 Full text not available from this repository.

Chapman, JM; Onnie, CM; Prescott, NJ; Fisher, SA; Mansfield, JC; Mathew, CG; Lewis, CM; Verzilli, CJ; Whittaker, JC; (2009) Searching for Genotype-Phenotype Structure: Using Hierarchical Log-Linear Models in Crohn Disease. American journal of human genetics, 84 (2). pp. 178-87. ISSN 0002-9297 DOI: https://doi.org/10.1016/j.ajhg.2008.12.015 Full text not available from this repository.

Elmasry, K; Ramus, S; Whittaker, J; Luo, Z; Gammerman, A; Lu, K; Ayhan, A; Singh, N; McGluggage, G; Jacobs, I; +1 more... Gayther, S; (2008) Genetic diagnosis and clinical outcome in patients with synchronous ovarian and endometrial cancer. [Conference or Workshop Item] http://researchonline.lshtm.ac.uk/id/eprint/8017 Full text not available from this repository.

Hunnangkul, S; Nitsch, D; Rhodes, B; Chadha, S; Roberton, CA; Pessôa-Lopes, P; Norsworthy, PJ; Fernando, MM; Charles, P; Mackworth-Young, C; +3 more... Isenberg, DA; Whittaker, JC; Vyse, TJ; (2008) Familial clustering of non-nuclear autoantibodies and C3 and C4 complement components in systemic lupus erythematosus. Arthritis and rheumatism, 58 (4). pp. 1116-1124. ISSN 0004-3591 DOI: https://doi.org/10.1002/art.23400 Full text not available from this repository.

Rhodes, B; Morris, DL; Subrahmanyan, L; Aubin, C; de Leon, CFM; Kelly, JF; Evans, DA; Whittaker, JC; Oksenberg, JR; de Jager, PL; +1 more... Vyse, TJ; (2008) Fine-mapping the genetic basis of CRP regulation in African Americans: a Bayesian approach. Human genetics, 123 (6). pp. 633-642. ISSN 0340-6717 DOI: https://doi.org/10.1007/s00439-008-0517-5 Full text not available from this repository.

Baksh, MF; Balding, DJ; Vyse, TJ; Whittaker, JC; (2006) A likelihood ratio approach to family-based association studies with covariates. Annals of human genetics, 70 (Pt 1). pp. 131-9. ISSN 0003-4800 DOI: https://doi.org/10.1111/j.1529-8817.2005.00189.x Full text not available from this repository.

Sibly, RM; Whittaker, JC; Talbot, M; (2001) A maximum-likelihood approach to fitting equilibrium models of microsatellite evolution. Molecular biology and evolution, 18 (3). pp. 413-7. ISSN 0737-4038 http://researchonline.lshtm.ac.uk/id/eprint/13632 Full text not available from this repository.

Whittaker, JC; Morris, AP; (2001) Family-based tests of association and/or linkage. Annals of human genetics, 65 (Pt 5). pp. 407-19. ISSN 0003-4800 DOI: https://doi.org/10.1017/S0003480001008818 Full text not available from this repository.