Items where Author is "Baker, DA"

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Number of items: 52.

2018

Benavente, ED; Oresegun, DR; de Sessions, PF; Walker, EM; Roper, C; Dombrowski, JG; de Souza, RM; Marinho, CRF; Sutherland, CJ; Hibberd, ML; +4 more... Mohareb, F; Baker, DA; Clark, TG; Campino, S; (2018) Global genetic diversity of var2csa in Plasmodium falciparum with implications for malaria in pregnancy and vaccine development. Scientific reports, 8 (1). p. 15429. ISSN 2045-2322 DOI: https://doi.org/10.1038/s41598-018-33767-3
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Fang, H; Gomes, AR; Klages, N; Pino, P; Maco, B; Walker, EM; Zenonos, ZA; Angrisano, F; Baum, J; Doerig, C; +3 more... Baker, DA; Billker, O; Brochet, M; (2018) Epistasis studies reveal redundancy among calcium-dependent protein kinases in motility and invasion of malaria parasites. Nature communications, 9 (1). p. 4248. ISSN 2041-1723 DOI: https://doi.org/10.1038/s41467-018-06733-w
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Large, Jonathan M; Birchall, Kristian; Bouloc, Nathalie S; Merritt, Andy T; Smiljanic-Hurley, Ela; Tsagris, Denise J; Wheldon, Mary C; Ansell, Keith H; Coombs, Peter J; Kettleborough, Catherine A; +5 more... Whalley, David; Stewart, Lindsay B; Bowyer, Paul W; Baker, David A; Osborne, Simon A; (2018) Potent inhibitors of malarial P. Falciparum protein kinase G: Improving the cell activity of a series of imidazopyridines. Bioorganic & medicinal chemistry letters. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2018.11.039
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Meerstein-Kessel, L; van der Lee, R; Stone, W; Lanke, K; Baker, DA; Alano, P; Silvestrini, F; Janse, CJ; Khan, SM; van de Vegte-Bolmer, M; +10 more... Graumans, W; Siebelink-Stoter, R; Kooij, TWA; Marti, M; Drakeley, C; Campo, JJ; van Dam, TJP; Sauerwein, R; Bousema, T; Huynen, MA; (2018) Probabilistic data integration identifies reliable gametocyte-specific proteins and transcripts in malaria parasites. Scientific reports, 8 (1). p. 410. ISSN 2045-2322 DOI: https://doi.org/10.1038/s41598-017-18840-7
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Perrin, AJ; Collins, CR; Russell, MRG; Collinson, LM; Baker, DA; Blackman, MJ; (2018) The Actinomyosin Motor Drives Malaria Parasite Red Blood Cell Invasion but Not Egress. mBio, 9 (4). ISSN 2150-7511 DOI: https://doi.org/10.1128/mBio.00905-18
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Tsagris, DJ; Birchall, K; Bouloc, N; Large, JM; Merritt, A; Smiljanic-Hurley, E; Wheldon, M; Ansell, KH; Kettleborough, C; Whalley, D; +4 more... Stewart, LB; Bowyer, PW; Baker, DA; Osborne, SA; (2018) Trisubstituted thiazoles as potent and selective inhibitors of Plasmodium falciparum protein kinase G (PfPKG). Bioorganic & medicinal chemistry letters. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2018.08.028 Item availability may be restricted.
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2017

Baker, DA; Stewart, LB; Large, JM; Bowyer, PW; Ansell, KH; Jiménez-Díaz, MB; El Bakkouri, M; Birchall, K; Dechering, KJ; Bouloc, NS; +19 more... Coombs, PJ; Whalley, D; Harding, DJ; Smiljanic-Hurley, E; Wheldon, MC; Walker, EM; Dessens, JT; Lafuente, MJ; Sanz, LM; Gamo, FJ; Ferrer, SB; Hui, R; Bousema, T; Angulo-Barturén, I; Merritt, AT; Croft, SL; Gutteridge, WE; Kettleborough, CA; Osborne, SA; (2017) A potent series targeting the malarial cGMP-dependent protein kinase clears infection and blocks transmission. Nature communications, 8 (1). p. 430. ISSN 2041-1723 DOI: https://doi.org/10.1038/s41467-017-00572-x
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Ganter, M; Goldberg, JM; Dvorin, JD; Paulo, JA; King, JG; Tripathi, AK; Paul, AS; Yang, J; Coppens, I; Jiang, RH; +5 more... Elsworth, B; Baker, DA; Dinglasan, RR; Gygi, SP; Duraisingh, MT; (2017) Plasmodium falciparum CRK4 directs continuous rounds of DNA replication during schizogony. Nature microbiology, 2. p. 17017. ISSN 2058-5276 DOI: https://doi.org/10.1038/nmicrobiol.2017.17
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2016

Campino, S; Benavente, ED; Assefa, S; Thompson, E; Drought, LG; Taylor, CJ; Gorvett, Z; Carret, CK; Flueck, C; Ivens, AC; +4 more... Kwiatkowski, DP; Alano, P; Baker, DA; Clark, TG; (2016) Genomic variation in two gametocyte non-producing Plasmodium falciparum clonal lines. Malaria journal, 15 (1). p. 229. ISSN 1475-2875 DOI: https://doi.org/10.1186/s12936-016-1254-1
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2015

Alam, MM; Solyakov, L; Bottrill, AR; Flueck, C; Siddiqui, FA; Singh, S; Mistry, S; Viskaduraki, M; Lee, K; Hopp, CS; +7 more... Chitnis, CE; Doerig, C; Moon, RW; Green, JL; Holder, AA; Baker, DA; Tobin, AB; (2015) Phosphoproteomics reveals malaria parasite Protein Kinase G as a signalling hub regulating egress and invasion. Nature communications, 6. p. 7285. ISSN 2041-1723 DOI: https://doi.org/10.1038/ncomms8285
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Green, JL; Moon, RW; Whalley, D; Bowyer, PW; Wallace, C; Rochani, A; Nageshan, RK; Howell, SA; Grainger, M; Jones, HM; +7 more... Ansell, KH; Chapman, TM; Taylor, DL; Osborne, SA; Baker, DA; Tatu, U; Holder, AA; (2015) Imidazopyridazine inhibitors of Plasmodium falciparum calcium dependent protein kinase 1 also target cGMP-dependent protein kinase and heat shock protein 90 to kill the parasite at different stages of intracellular development. Antimicrobial agents and chemotherapy, 60 (3). pp. 1464-75. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.01748-15
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Guenot, M; Loizon, S; Howard, J; Costa, G; Baker, DA; Mohabeer, SY; Troye-Blomberg, M; Moreau, JF; Déchanet-Merville, J; Mercereau-Puijalon, O; +2 more... Mamani-Matsuda, M; Behr, C; (2015) PHOSPHOANTIGEN BURST UPON PLASMODIUM FALCIPARUM SCHIZONT RUPTURE CAN DISTANTLY ACTIVATE VGAMMA9-VDELTA2 T-CELLS. Infection and immunity, 83 (10). pp. 3816-24. ISSN 0019-9567 DOI: https://doi.org/10.1128/IAI.00446-15
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Ramdani, G; Naissant, B; Thompson, E; Breil, F; Lorthiois, A; Dupuy, F; Cummings, R; Duffier, Y; Corbett, Y; Mercereau-Puijalon, O; +5 more... Vernick, K; Taramelli, D; Baker, DA; Langsley, G; Lavazec, C; (2015) cAMP-Signalling Regulates Gametocyte-Infected Erythrocyte Deformability Required for Malaria Parasite Transmission. PLoS pathogens, 11 (5). e1004815. ISSN 1553-7366 DOI: https://doi.org/10.1371/journal.ppat.1004815
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2014

Brochet, M; Collins, MO; Smith, TK; Thompson, E; Sebastian, S; Volkmann, K; Schwach, F; Chappell, L; Gomes, AR; Berriman, M; +4 more... Rayner, JC; Baker, DA; Choudhary, J; Billker, O; (2014) Phosphoinositide Metabolism Links cGMP-Dependent Protein Kinase G to Essential Ca2+ Signals at Key Decision Points in the Life Cycle of Malaria Parasites. PLoS biology, 12 (3). e1001806. ISSN 1544-9173 DOI: https://doi.org/10.1371/journal.pbio.1001806
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Flueck, C; Baker, DA; (2014) Malaria parasite epigenetics: when virulence and romance collide. Cell host & microbe, 16 (2). pp. 148-50. ISSN 1931-3128 DOI: https://doi.org/10.1016/j.chom.2014.07.012 Full text not available from this repository.

Kafsack, BF; Rovira-Graells, N; Clark, TG; Bancells, C; Crowley, VM; Campino, SG; Williams, AE; Drought, LG; Kwiatkowski, DP; Baker, DA; +2 more... Cortés, A; Llinás, M; (2014) A transcriptional switch underlies commitment tosexual development in malaria parasites. Nature, 507 (7491). pp. 248-52. ISSN 0028-0836 DOI: https://doi.org/10.1038/nature12920
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Kafsack, BFC; Rovira-Graells, N; Clark, TG; Bancells, C; Crowley, VM; Campino, SG; Williams, AE; Drought, LG; Kwiatkowski, DP; Baker, DA; +2 more... Cortés, A; Llinás, M; (2014) A transcriptional switch underlies commitment tosexual development in malaria parasites. Nature. ISSN 0028-0836 DOI: https://doi.org/10.1038/nature12920 Full text not available from this repository.

Lavogina, D; Budu, A; Enkvist, E; Hopp, CS; Baker, DA; Langsley, G; Garcia, CR; Uri, A; (2014) Targeting Plasmodium falciparum protein kinases with adenosine analogue-oligoarginine conjugates. Experimental parasitology. ISSN 0014-4894 DOI: https://doi.org/10.1016/j.exppara.2014.02.001 Full text not available from this repository.

2013

Collins, CR; Hackett, F; Strath, M; Penzo, M; Withers-Martinez, C; Baker, DA; Blackman, MJ; (2013) Malaria Parasite cGMP-dependent Protein Kinase Regulates Blood Stage Merozoite Secretory Organelle Discharge and Egress. PLoS pathogens, 9 (5). ISSN 1553-7366 DOI: https://doi.org/10.1371/journal.ppat.1003344
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2012

2010

Baker, DA; (2010) Cyclic nucleotide signalling in malaria parasites. Cellular microbiology. ISSN 1462-5814 DOI: https://doi.org/10.1111/j.1462-5822.2010.01561.x Full text not available from this repository.

Baker, DA; (2010) Malaria Gametocytogenesis. Molecular and biochemical parasitology. ISSN 0166-6851 DOI: https://doi.org/10.1016/j.molbiopara.2010.03.019
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Dvorin, JD; Martyn, DC; Patel, SD; Grimley, JS; Collins, CR; Hopp, CS; Bright, AT; Westenberger, S; Winzeler, E; Blackman, MJ; +3 more... Baker, DA; Wandless, TJ; Duraisingh, MT; (2010) A plant-like kinase in Plasmodium falciparum regulates parasite egress from erythrocytes. Science (New York, NY), 328 (5980). pp. 910-2. ISSN 0036-8075 DOI: https://doi.org/10.1126/science.1188191 Full text not available from this repository.

2009

Doerig, C; Baker, D; Billker, O; Blackman, MJ; Chitnis, C; Dhar Kumar, S; Heussler, V; Holder, AA; Kocken, C; Krishna, S; +11 more... Langsley, G; Lasonder, E; Menard, R; Meissner, M; Pradel, G; Ranford-Cartwright, L; Sharma, A; Sharma, P; Tardieux, T; Tatu, U; Alano, P; (2009) Signalling in malaria parasites. The MALSIG consortium. Parasite (Paris, France), 16 (3). pp. 169-82. ISSN 1252-607X DOI: https://doi.org/10.1051/parasite/2009163169 Full text not available from this repository.

Leber, W; Skippen, A; Fivelman, QL; Bowyer, PW; Cockcroft, S; Baker, DA; (2009) A unique phosphatidylinositol 4-phosphate 5-kinase is activated by ADP-ribosylation factor in Plasmodium falciparum. International journal for parasitology, 39 (6). pp. 645-53. ISSN 0020-7519 DOI: https://doi.org/10.1016/j.ijpara.2008.11.015 Full text not available from this repository.

Moon, RW; Taylor, CJ; Bex, C; Schepers, R; Goulding, D; Janse, CJ; Waters, AP; Baker, DA; Billker, O; (2009) A cyclic GMP signalling module that regulates gliding motility in a malaria parasite. PLoS pathogens, 5 (9). e1000599. ISSN 1553-7366 DOI: https://doi.org/10.1371/journal.ppat.1000599
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Schnick, C; Polley, SD; Fivelman, QL; Ranford-Cartwright, LC; Wilkinson, SR; Brannigan, JA; Wilkinson, AJ; Baker, DA; (2009) Structure and non-essential function of glycerol kinase in Plasmodium falciparum blood stages. Molecular microbiology, 71 (2). pp. 533-545. ISSN 0950-382X DOI: https://doi.org/10.1111/j.1365-2958.2008.06544.x
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Taylor, HM; McRobert, L; Grainger, M; Sicard, A; Dluzewski, AR; Hopp, CS; Holder, AA; Baker, DA; (2009) The malaria parasite cGMP-dependent protein kinase plays a central role in blood stage schizogony. Eukaryotic cell, 9 (1). pp. 37-45. ISSN 1535-9778 DOI: https://doi.org/10.1128/EC.00186-09 Full text not available from this repository.

2008

McRobert, L; Taylor, CJ; Deng, W; Fivelman, Q; Cummings, R; Billker, O; Baker, DA; (2008) P-falciparum gametogenesis is mediated by cGMPdependent protein kinase. [Conference or Workshop Item] http://researchonline.lshtm.ac.uk/id/eprint/7854 Full text not available from this repository.

Taylor, HM; McRobert, L; Grainger, M; Holder, AA; Baker, DA; (2008) Plasmodium falciparum cGMP-dependent protein kinase plays a central role in schizogony. [Conference or Workshop Item] http://researchonline.lshtm.ac.uk/id/eprint/7853 Full text not available from this repository.

2007

Fivelman, QL; McRobert, L; Sharp, S; Taylor, CJ; Saeed, M; Swales, CA; Sutherland, CJ; Baker, DA; (2007) Improved synchronous production of Plasmodium falciparum gametocytes in vitro. Molecular and biochemical parasitology, 154 (1). pp. 119-23. ISSN 0166-6851 DOI: https://doi.org/10.1016/j.molbiopara.2007.04.008 Full text not available from this repository.

2006

Kelly, JM; McRobert, L; Baker, DA; (2006) Evidence on the chromosomal location of centromeric DNA in Plasmodium falciparum from etoposide-mediated topoisomerase-II cleavage. Proceedings of the National Academy of Sciences of the United States of America, 103 (17). pp. 6706-11. ISSN 0027-8424 DOI: https://doi.org/10.1073/pnas.0510363103 Full text not available from this repository.

Sharp, S; Lavstsen, T; Fivelman, QL; Saeed, M; McRobert, L; Templeton, TJ; Jensen, AT; Baker, DA; Theander, TG; Sutherland, CJ; (2006) Programmed Transcription of the var Gene Family, but not of stevor, in Plasmodium falciparum Gametocytes. Eukaryotic cell, 5 (8). pp. 1206-14. ISSN 1535-9778 DOI: https://doi.org/10.1128/EC.00029-06 Full text not available from this repository.

2005

Baker, DA; Lastname, F; Deng, W; (2005) Cyclic GMP-dependent protein kinases in protozoa. Frontiers in bioscience (Landmark edition), 10. pp. 1229-38. ISSN 1093-4715 DOI: https://doi.org/10.2741/1615 Full text not available from this repository.

Young, JA; Fivelman, QL; Blair, PL; de la Vega, P; Le Roch, KG; Zhou, Y; Carucci, DJ; Baker, DA; Winzeler, EA; (2005) The Plasmodium falciparum sexual development transcriptome: A microarray analysis using ontology-based pattern identification. Molecular and biochemical parasitology, 143 (1). pp. 67-79. ISSN 0166-6851 DOI: https://doi.org/10.1016/j.molbiopara.2005.05.007 Full text not available from this repository.

2004

Baker, D; (2004) Adenylyl and guanylyl cyclases from the malaria parasite Plasmodium falciparum. IUBMB life, 56 (9). pp. 535-40. ISSN 1521-6543 DOI: https://doi.org/10.1080/15216540400013937 Full text not available from this repository.

Baker, DA; Kelly, JM; (2004) Structure, function and evolution of microbial adenylyl and guanylyl cyclases. Molecular microbiology, 52 (5). pp. 1229-42. ISSN 0950-382X DOI: https://doi.org/10.1111/j.1365-2958.2004.04067.x Full text not available from this repository.

Baker, DA; Kelly, JM; (2004) Purine nucleotide cyclases in the malaria parasite. Trends in parasitology, 20 (5). pp. 227-32. ISSN 1471-4922 DOI: https://doi.org/10.1016/j.pt.2004.02.007 Full text not available from this repository.

2003

Deng, W; Parbhu-Patel, A; Meyer, DJ; Baker, DA; (2003) The role of two novel regulatory sites in the activation of the cGMP-dependent protein kinase from Plasmodium falciparum. The Biochemical journal, 374 (Pt 2). pp. 559-65. ISSN 0264-6021 DOI: https://doi.org/10.1042/BJ20030474 Full text not available from this repository.

Muhia, DK; Swales, CA; Eckstein-Ludwig, U; Saran, S; Polley, SD; Kelly, JM; Schaap, P; Krishna, S; Baker, DA; (2003) Multiple Splice Variants Encode a Novel Adenylyl Cyclase of Possible Plastid Origin Expressed in the Sexual Stage of the Malaria Parasite Plasmodium falciparum. The Journal of biological chemistry, 278 (24). pp. 22014-22. ISSN 0021-9258 DOI: https://doi.org/10.1074/jbc.M301639200 Full text not available from this repository.

2002

Deng, W; Baker, DA; (2002) A novel cyclic GMP-dependent protein kinase is expressed in the ring stage of the Plasmodium falciparum life cycle. Molecular microbiology, 44 (5). pp. 1141-51. ISSN 0950-382X DOI: https://doi.org/10.1046/j.1365-2958.2002.02948.x Full text not available from this repository.

2001

LI, JL; Targett, GA; Baker, DA; (2001) Primary structure and sexual stage-specific expression of a LAMMER protein kinase of Plasmodium falciparum. International journal for parasitology, 31 (4). pp. 387-92. ISSN 0020-7519 http://researchonline.lshtm.ac.uk/id/eprint/16259 Full text not available from this repository.

This list was generated on Wed Jan 23 07:57:49 2019 GMT.