Items where Author is "Taylor, MC"

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Number of items: 57.

2019

Foscolos, Angeliki-Sofia; Papanastasiou, Ioannis; Tsotinis, Andrew; Taylor, Martin C; Kelly, John M; (2019) Synthesis and evaluation of new nifurtimox-adamantane adducts with trypanocidal activity. ChemMedChem. ISSN 1860-7179 DOI: https://doi.org/10.1002/cmdc.201900165 Item availability may be restricted.
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Georgiadis, Markos-Orestis; Kourbeli, Violeta; Ioannidou, Vaya; Karakitsios, Evangelos; Papanastasiou, Ioannis; Tsotinis, Andrew; Komiotis, Dimitri; Vocat, Anthony; Cole, Stewart T; Taylor, Martin C; +1 more... Kelly, John M; (2019) Synthesis of diphenoxyadamantane alkylamines with pharmacological interest. Bioorganic & medicinal chemistry letters, 29 (11). pp. 1278-1281. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2019.04.010 Item availability may be restricted.
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MacGregor, Paula; Gonzalez-Munoz, Andrea L; Jobe, Fatoumatta; Taylor, Martin C; Rust, Steven; Sandercock, Alan M; Macleod, Olivia JS; Van Bocxlaer, Katrien; Francisco, Amanda F; D'Hooge, Francois; +7 more... Tiberghien, Arnaud; Barry, Conor S; Howard, Philip; Higgins, Matthew K; Vaughan, Tristan J; Minter, Ralph; Carrington, Mark; (2019) A single dose of antibody-drug conjugate cures a stage 1 model of African trypanosomiasis. PLoS neglected tropical diseases, 13 (5). ISSN 1935-2727 DOI: https://doi.org/10.1371/journal.pntd.0007373
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2018

Bistrović, A; Krstulović, L; Stolić, I; Drenjančević, D; Talapko, J; Taylor, MC; Kelly, JM; Bajić, M; Raić-Malić, S; (2018) Synthesis, anti-bacterial and anti-protozoal activities of amidinobenzimidazole derivatives and their interactions with DNA and RNA. Journal of enzyme inhibition and medicinal chemistry, 33 (1). pp. 1323-1334. ISSN 1475-6366 DOI: https://doi.org/10.1080/14756366.2018.1484733
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Ghashghaei, O; Kielland, N; Revés, M; Taylor, MC; Kelly, JM; Di Pietro, O; Muñoz-Torrero, D; Pérez, B; Lavilla, R; (2018) Tetrasubstituted Imidazolium Salts as Potent Antiparasitic Agents against African and American Trypanosomiases. Molecules (Basel, Switzerland), 23 (1). ISSN 1420-3049 DOI: https://doi.org/10.3390/molecules23010177
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2017

Taylor, MC; Ward, TH; (2017) Pathogen imaging applications. Methods (San Diego, Calif), 127. pp. 1-2. ISSN 1046-2023 DOI: https://doi.org/10.1016/j.ymeth.2017.08.011
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2016

Sola, I; Artigas, A; Taylor, MC; Pérez-Areales, FJ; Viayna, E; Clos, MV; Pérez, B; Wright, CW; Kelly, JM; Muñoz-Torrero, D; (2016) Synthesis and biological evaluation of N-cyanoalkyl-, N-aminoalkyl-, and N-guanidinoalkyl-substituted 4-aminoquinoline derivatives as potent, selective, brain permeable antitrypanosomal agents. Bioorganic & medicinal chemistry. ISSN 0968-0896 DOI: https://doi.org/10.1016/j.bmc.2016.08.036
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2015

Di Pietro, O; Vicente-García, E; Taylor, MC; Berenguer, D; Viayna, E; Lanzoni, A; Sola, I; Sayago, H; Riera, C; Fisa, R; +5 more... Clos, MV; Pérez, B; Kelly, JM; Lavilla, R; Muñoz-Torrero, D; (2015) Multicomponent reaction-based synthesis and biological evaluation of tricyclic heterofused quinolines with multi-trypanosomatid activity. European journal of medicinal chemistry, 105. pp. 120-137. ISSN 0223-5234 DOI: https://doi.org/10.1016/j.ejmech.2015.10.007
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Sola, I; Castellà, S; Viayna, E; Galdeano, C; Taylor, MC; Gbedema, SY; Pérez, B; Clos, MV; Jones, DC; Fairlamb, AH; +3 more... Wright, CW; Kelly, JM; Muñoz-Torrero, D; (2015) Synthesis, biological profiling and mechanistic studies of 4-aminoquinoline-based heterodimeric compounds with dual trypanocidal-antiplasmodial activity. Bioorganic & medicinal chemistry, 23 (16). pp. 5156-67. ISSN 0968-0896 DOI: https://doi.org/10.1016/j.bmc.2015.01.031 Full text not available from this repository.

2014

Campos, MC; Leon, LL; Taylor, MC; Kelly, JM; (2014) Benznidazole-resistance in Trypanosoma cruzi: evidence that distinct mechanisms can act in concert. Molecular and biochemical parasitology, 193 (1). pp. 17-9. ISSN 0166-6851 DOI: https://doi.org/10.1016/j.molbiopara.2014.01.002
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Shameer, S; Logan-Klumpler, FJ; Vinson, F; Cottret, L; Merlet, B; Achcar, F; Boshart, M; Berriman, M; Breitling, R; Bringaud, F; +31 more... Bütikofer, P; Cattanach, AM; Bannerman-Chukualim, B; Creek, DJ; Crouch, K; de Koning, HP; Denise, H; Ebikeme, C; Fairlamb, AH; Ferguson, MA; Ginger, ML; Hertz-Fowler, C; Kerkhoven, EJ; Mäser, P; Michels, PA; Nayak, A; Nes, DW; Nolan, DP; Olsen, C; Silva-Franco, F; Smith, TK; Taylor, MC; Tielens, AG; Urbaniak, MD; van Hellemond, JJ; Vincent, IM; Wilkinson, SR; Wyllie, S; Opperdoes, FR; Barrett, MP; Jourdan, F; (2014) TrypanoCyc: a community-led biochemical pathways database for Trypanosoma brucei. Nucleic acids research. ISSN 0305-1048 DOI: https://doi.org/10.1093/nar/gku944
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Sola, I; Artigas, A; Taylor, MC; Gbedema, SY; Pérez, B; Clos, MV; Wright, CW; Kelly, JM; Muñoz-Torrero, D; (2014) Synthesis and antiprotozoal activity of oligomethylene- and p-phenylene-bis(methylene)-linked bis(+)-huprines. Bioorganic & medicinal chemistry letters, 24 (23). pp. 5435-5438. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2014.10.025 Full text not available from this repository.

Taylor, MC; Kelly, JM; (2014) Optimizing bioluminescence imaging to study protozoan parasite infections. Trends in parasitology, 30 (4). pp. 161-2. ISSN 1471-4922 DOI: https://doi.org/10.1016/j.pt.2014.01.006 Full text not available from this repository.

2013

Koperniku, A; Papanastasiou, I; Foscolos, GB; Tsotinis, A; Taylor, MC; Kelly, JM; (2013) Synthesis and trypanocidal action of new adamantane substituted imidazolines. MedChemComm, 4 (5). pp. 856-859. ISSN 2040-2503 DOI: https://doi.org/10.1039/c3md00081h Full text not available from this repository.

Myburgh, E; Coles, J; Ritchie, R; Kennedy, PGE; McLatchie, AP; Rodgers, R; Taylor, MC; Barrett, MP; Brewer, JM; Mottram, JC; (2013) In Vivo Imaging of Trypanosome-Brain Interactions and Development of a Rapid Screening Test for Drugs against CNS Stage Trypanosomiasis. PLoS neglected tropical diseases, 7 (8). ISSN 1935-2727 DOI: https://doi.org/10.1371/journal.pntd.0002384.
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2012

Kelly, JM; Taylor, MC; Horn, D; Loza, E; Kalvinsh, I; Björkling, F; (2012) Inhibitors of human histone deacetylase with potent activity against the African trypanosome Trypanosoma brucei. Bioorganic & medicinal chemistry letters, 22 (5). pp. 1886-90. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2012.01.072
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Mejia, AM; Hall, BS; Taylor, MC; Gómez-Palacio, A; Wilkinson, SR; Triana-Chávez, O; Kelly, JM; (2012) Benznidazole-Resistance in Trypanosoma cruzi Is a Readily Acquired Trait That Can Arise Independently in a Single Population. The Journal of infectious diseases, 206 (2). pp. 220-8. ISSN 0022-1899 DOI: https://doi.org/10.1093/infdis/jis331
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Torres, E; Duque, MD; Lopez-Querol, M; Taylor, MC; Naesens, L; Ma, CL; Pinto, LH; Sureda, FX; Kelly, JM; Vazquez, S; (2012) Synthesis of benzopolycyclic cage amines: NMDA receptor antagonist, trypanocidal and antiviral activities. Bioorganic & medicinal chemistry, 20 (2). pp. 942-948. ISSN 0968-0896 DOI: https://doi.org/10.1016/j.bmc.2011.11.050 Full text not available from this repository.

2011

Defaux, J; Sala, M; Formosa, X; Galdeano, C; Taylor, MC; Alobaid, WAA; Kelly, JM; Wright, CW; Camps, P; Munoz-Torrero, D; (2011) Huprines as a new family of dual acting trypanocidal-antiplasmodial agents. Bioorganic & medicinal chemistry, 19 (5). pp. 1702-1707. ISSN 0968-0896 DOI: https://doi.org/10.1016/j.bmc.2011.01.028
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Obado, SO; Bot, C; Echeverry, MC; Bayona, JC; Alvarez, VE; Taylor, MC; Kelly, JM; (2011) Centromere-associated topoisomerase activity in bloodstream form Trypanosoma brucei. Nucleic acids research, 39 (3). pp. 1023-33. ISSN 0305-1048 DOI: https://doi.org/10.1093/nar/gkq839
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Taylor, MC; Huang, H; Kelly, JM; (2011) Genetic Techniques in Trypanosoma cruzi. Advances in parasitology, 75. pp. 231-50. ISSN 0065-308X DOI: https://doi.org/10.1016/B978-0-12-385863-4.00011-3 Full text not available from this repository.

2010

Bot, C; Hall, BS; Bashir, N; Taylor, MC; Helsby, NA; Wilkinson, SR; (2010) Trypanocidal activity of aziridinyl nitrobenzamide prodrugs. Antimicrobial agents and chemotherapy, 54 (10). pp. 4246-52. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.00800-10 Full text not available from this repository.

2008

Taylor, MC; Kaur, H; Blessington, B; Kelly, JM; Wilkinson, SR; (2008) Validation of spermidine synthase as a drug target in African trypanosomes. The Biochemical journal, 409 (2). pp. 563-9. ISSN 0264-6021 DOI: https://doi.org/10.1042/BJ20071185 Full text not available from this repository.

Wilkinson, SR; Taylor, MC; Horn, D; Kelly, JM; Cheeseman, I; (2008) A mechanism for cross-resistance to nifurtimox and benznidazole in trypanosomes. Proceedings of the National Academy of Sciences of the United States of America, 105 (13). pp. 5022-7. ISSN 0027-8424 DOI: https://doi.org/10.1073/pnas.0711014105 Full text not available from this repository.

2007

Piacenza, L; Irigoi­n, F; Alvarez, MN; Peluffo, G; Taylor, MC; Kelly, JM; Wilkinson, SR; Radi, R; (2007) Mitochondrial superoxide radicals mediate programmed cell death in Trypanosoma cruzi: cytoprotective action of mitochondrial iron superoxide dismutase overexpression. The Biochemical journal, 403 (2). pp. 323-34. ISSN 0264-6021 DOI: https://doi.org/10.1042/BJ20061281 Full text not available from this repository.

2006

Wilkinson, SR; Prathalingam, SR; Taylor, MC; Ahmed, A; Horn, D; Kelly, JM; (2006) Functional characterisation of the iron superoxide dismutase gene repertoire in Trypanosoma brucei. Free radical biology & medicine, 40 (2). pp. 198-209. ISSN 0891-5849 DOI: https://doi.org/10.1016/j.freeradbiomed.2005.06.022 Full text not available from this repository.

2005

Kelly, JM; Taylor, MC; Wilkinson, SR; (2005) Trypanosoma cruzi. In: Fuchs, J; Podda, M; Goethe, JW, (eds.) Encyclopedia of Diagnostic Genomics and Proteomics. Marcel Dekker, Inc., New York, USA, pp. 1297-1301. http://researchonline.lshtm.ac.uk/id/eprint/15644 Full text not available from this repository.

Wilkinson, SR; Prathalingam, SR; Taylor, MC; Horn, D; Kelly, JM; (2005) Vitamin C biosynthesis in trypanosomes: A role for the glycosome. Proceedings of the National Academy of Sciences of the United States of America, 102. pp. 11645-11650. ISSN 0027-8424 DOI: https://doi.org/10.1073/pnas.0504251102 Full text not available from this repository.

2004

McRobert, L; Preiser, P; Sharp, S; Jarra, W; Kaviratne, M; Taylor, MC; Renia, L; Sutherland, CJ; (2004) Distinct Trafficking and Localization of STEVOR Proteins in Three Stages of the Plasmodium falciparum Life Cycle. Infection and immunity, 72 (11). pp. 6597-602. ISSN 0019-9567 DOI: https://doi.org/10.1128/IAI.72.11.6597-6602.2004 Full text not available from this repository.

2003

Gaunt, MW; Yeo, M; Frame, IA; Stothard, JR; Carrasco, HJ; Taylor, MC; Mena, SS; Veazey, P; Miles, GA; Acosta, N; +2 more... de Arias, AR; Miles, MA; (2003) Mechanism of genetic exchange in American trypanosomes. Nature, 421 (6926). pp. 936-9. ISSN 0028-0836 DOI: https://doi.org/10.1038/nature01438 Full text not available from this repository.

2002

Taylor, MC; Kelly, JM; (2002) Functional dissection of the Trypanosoma cruzi genome: New approaches in a new era. In: Tyler, K; Miles, MA, (eds.) American Trypanosomiasis. Kluwer Academic Publishers, London, pp. 57-68. http://researchonline.lshtm.ac.uk/id/eprint/15544 Full text not available from this repository.

This list was generated on Mon Jun 24 12:03:57 2019 BST.