Items where Author is "Fletcher, H"

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Abebe, M; Doherty, TM; Wassie, L; Aseffa, A; Bobosha, K; Demissie, A; Zewdie, M; Engers, H; Andersen, P; Kim, L; +7 more... Huggett, J; Rook, G; Yamuah, LK; Zumla, A; VACSEL study group, . (, inc; Fletcher, H; ); (2010) Expression of apoptosis-related genes in an Ethiopian cohort study correlates with tuberculosis clinical status. European journal of immunology, 40 (1). pp. 291-301. ISSN 0014-2980 DOI: https://doi.org/10.1002/eji.200939856 Full text not available from this repository.

Andrews, JR; Nemes, E; Tameris, M; Landry, BS; Mahomed, H; McClain, JB; Fletcher, HA; Hanekom, WA; Wood, R; McShane, H; +2 more... Scriba, TJ; Hatherill, M; (2017) Serial QuantiFERON testing and tuberculosis disease risk among young children: an observational cohort study. The lancet Respiratory medicine, 5 (4). pp. 282-290. ISSN 2213-2600 DOI: https://doi.org/10.1016/S2213-2600(17)30060-7
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Berthoud, TK; Dunachie, SJ; Todryk, S; Hill, AV; Fletcher, HA; (2009) MIG (CXCL9) is a more sensitive measure than IFN-gamma of vaccine induced T-cell responses in volunteers receiving investigated malaria vaccines. Journal of immunological methods, 340 (1). pp. 33-41. ISSN 0022-1759 DOI: https://doi.org/10.1016/j.jim.2008.09.021
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Berthoud, TK; Fletcher, H; Porter, D; Thompson, F; Hill, AV; Todryk, SM; (2009) Comparing human T cell and NK cell responses in viral-based malaria vaccine trials. Vaccine, 28 (1). pp. 21-7. ISSN 0264-410X DOI: https://doi.org/10.1016/j.vaccine.2009.09.132 Full text not available from this repository.

Berthoud, TK; Hamill, M; Lillie, PJ; Hwenda, L; Collins, KA; Ewer, KJ; Milicic, A; Poyntz, HC; Lambe, T; Fletcher, HA; +2 more... Hill, AV; Gilbert, SC; (2011) Potent CD8+ T-cell immunogenicity in humans of a novel heterosubtypic influenza A vaccine, MVA-NP+M1. Clinical infectious diseases, 52 (1). pp. 1-7. ISSN 1058-4838 DOI: https://doi.org/10.1093/cid/ciq015
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Beveridge, NE; Fletcher, HA; Hughes, J; Pathan, AA; Scriba, TJ; Minassian, A; Sander, CR; Whelan, KT; Dockrell, HM; Hill, AV; +2 more... Hanekom, WA; McShane, H; (2008) A comparison of IFNgamma detection methods used in tuberculosis vaccine trials. Tuberculosis (Edinburgh, Scotland), 88 (6). pp. 631-40. ISSN 1472-9792 DOI: https://doi.org/10.1016/j.tube.2008.06.005 Full text not available from this repository.

Brennan, MJ; Tanner, R; Morris, S; Scriba, TJ; Achkar, JM; Zelmer, A; Hokey, D; Izzo, A; Sharpe, S; Williams, A; +6 more... Penn-Nicholson, A; Erasmus, M; Stylianou, E; Hoft, DF; McShane, H; Fletcher, HA; (2017) The Cross-species Mycobacterial Growth Inhibition Assay (MGIA) Project 2010-2014. Clinical and vaccine immunology. ISSN 1556-6811 DOI: https://doi.org/10.1128/CVI.00142-17
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Brookes, RH; Hill, PC; Owiafe, PK; Ibanga, HB; Jeffries, DJ; Donkor, SA; Fletcher, HA; Hammond, AS; Lienhardt, C; Adegbola, RA; +2 more... McShane, H; Hill, AV; (2008) Safety and immunogenicity of the candidate tuberculosis vaccine MVA85A in West Africa. PloS one, 3 (8). e2921. ISSN 1932-6203 DOI: https://doi.org/10.1371/journal.pone.0002921
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Chen, T; Blanc, C; Eder, AZ; Prados-Rosales, R; Souza, AC; Kim, RS; Glatman-Freedman, A; Joe, M; Bai, Y; Lowary, TL; +6 more... Tanner, R; Brennan, MJ; Fletcher, HA; McShane, H; Casadevall, A; Achkar, JM; (2016) Association of Human Antibodies to Arabinomannan With Enhanced Mycobacterial Opsonophagocytosis and Intracellular Growth Reduction. The Journal of infectious diseases, 214 (2). pp. 300-10. ISSN 0022-1899 DOI: https://doi.org/10.1093/infdis/jiw141 Full text not available from this repository.

Demissie, A; Abebe, M; Aseffa, A; Rook, G; Fletcher, H; Zumla, A; Weldingh, K; Brock, I; Andersen, P; Doherty, TM; +1 more... VACSEL Study Group; (2004) Healthy individuals that control a latent infection with Mycobacterium tuberculosis express high levels of Th1 cytokines and the IL-4 antagonist IL-4delta2. Journal of immunology (Baltimore, Md, 172 (11). pp. 6938-43. ISSN 0022-1767 DOI: https://doi.org/10.4049/jimmunol.172.11.6938 Full text not available from this repository.

Demissie, A; Leyten, EM; Abebe, M; Wassie, L; Aseffa, A; Abate, G; Fletcher, H; Owiafe, P; Hill, PC; Brookes, R; +8 more... Rook, G; Zumla, A; Arend, SM; Klein, M; Ottenhoff, TH; Andersen, P; Doherty, TM; VACSEL Study Group; (2006) Recognition of stage-specific mycobacterial antigens differentiates between acute and latent infections with Mycobacterium tuberculosis. Clinical and vaccine immunology, 13 (2). pp. 179-86. ISSN 1556-6811 DOI: https://doi.org/10.1128/CVI.13.2.179-186.2006 Full text not available from this repository.

Dutruel, C; Thole, J; Geels, M; Mollenkopf, HJ; Ottenhoff, T; Guzman, CA; Fletcher, HA; Leroy, O; Kaufmann, SH; (2014) TRANSVAC workshop on standardisation and harmonisation of analytical platforms for HIV, TB and malaria vaccines: 'How can big data help?'. Vaccine. ISSN 0264-410X DOI: https://doi.org/10.1016/j.vaccine.2014.06.014
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Ferns, RB; Fletcher, H; Bradley, S; Mackinnon, S; Hunt, C; Tedder, RS; (2002) The prospective evaluation of a nested polymerase chain reaction assay for the early detection of Aspergillus infection in patients with leukaemia or undergoing allograft treatment. British journal of haematology, 119 (3). pp. 720-5. ISSN 0007-1048 DOI: https://doi.org/10.1046/j.1365-2141.2002.03862.x Full text not available from this repository.

Fletcher, H; (2015) Profiling the host immune response to tuberculosis vaccines. Vaccine. ISSN 0264-410X DOI: https://doi.org/10.1016/j.vaccine.2015.07.090 Full text not available from this repository.

Fletcher, H; McShane, H; (2006) Tuberculosis vaccines: current status and future prospects. Expert opinion on emerging drugs, 11 (2). pp. 207-15. ISSN 1472-8214 DOI: https://doi.org/10.1517/14728214.11.2.207 Full text not available from this repository.

Fletcher, HA; (2007) Correlates of immune protection from tuberculosis. Current molecular medicine, 7 (3). pp. 319-25. ISSN 1566-5240 DOI: https://doi.org/10.2174/156652407780598520 Full text not available from this repository.

Fletcher, HA; (2001) Molecular epidemiology of tuberculosis: recent developments and applications. Current opinion in pulmonary medicine, 7 (3). pp. 154-9. ISSN 1070-5287 http://researchonline.lshtm.ac.uk/id/eprint/1217160 Full text not available from this repository.

Fletcher, HA; (2018) Systems approaches to correlates of protection and progression to TB disease. Seminars in immunology. ISSN 1044-5323 DOI: https://doi.org/10.1016/j.smim.2018.10.001 Full text not available from this repository.

Fletcher, HA; Chatterjee, M; Cooper, A; Hussell, T; Kaye, PM; Prior, J; Reljic, R; Vermaak, S; Vordermeier, M; Williams, A; +1 more... McShane, H; (2018) VALIDATE: Exploiting the synergy between complex intracellular pathogens to expedite vaccine research and development for tuberculosis, leishmaniasis, melioidosis and leprosy. F1000Research, 7. p. 485. ISSN 2046-1402 DOI: https://doi.org/10.12688/f1000research.14386.1
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Fletcher, HA; Donoghue, HD; Holton, J; Pap, I; Spigelman, M; (2003) Widespread occurrence of Mycobacterium tuberculosis DNA from 18th-19th century Hungarians. American journal of physical anthropology, 120 (2). pp. 144-52. ISSN 0002-9483 DOI: https://doi.org/10.1002/ajpa.10114 Full text not available from this repository.

Fletcher, HA; Donoghue, HD; Taylor, GM; van der Zanden, AG; Spigelman, M; (2003) Molecular analysis of Mycobacterium tuberculosis DNA from a family of 18th century Hungarians. Microbiology (Reading, England), 149 (Pt 1). pp. 143-51. ISSN 1350-0872 DOI: https://doi.org/10.1099/mic.0.25961-0 Full text not available from this repository.

Fletcher, HA; Filali-Mouhim, A; Nemes, E; Hawkridge, A; Keyser, A; Njikan, S; Hatherill, M; Scriba, TJ; Abel, B; Kagina, BM; +32 more... Veldsman, A; Agudelo, NM; Kaplan, G; Hussey, GD; Sekaly, RP; Hanekom, WA; BCG study team; , COLLABORATORS; Minnies, D; Tanner, R; Chung, CK; Cameron, MJ; Goulet, JP; Gaujoux, R; Hughes, J; Gelderbloem, S; Iloni, K; Buchanan, M; van der Merwe, L; Burger, A; Denation, L; Mlanjeni, S; Abrahams, S; Shepherd, R; Geldenhuys, M; Seoighe, C; Soares, A; Gamieldien, H; Sidibana, M; Mahomed, H; McShane, H; Hill, AV; (2016) Human newborn bacille Calmette-Guérin vaccination and risk of tuberculosis disease: a case-control study. BMC medicine, 14 (1). p. 76. ISSN 1741-7015 DOI: https://doi.org/10.1186/s12916-016-0617-3
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Fletcher, HA; Hawkridge, T; McShane, H; (2009) A New Vaccine for Tuberculosis: The Challenges of Development and Deployment. Journal of bioethical inquiry, 6 (2). pp. 219-228. ISSN 1176-7529 DOI: https://doi.org/10.1007/s11673-009-9153-6
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Fletcher, HA; Keyser, A; Bowmaker, M; Sayles, PC; Kaplan, G; Hussey, G; Hill, AV; Hanekom, WA; (2009) Transcriptional profiling of mycobacterial antigen-induced responses in infants vaccinated with BCG at birth. BMC medical genomics, 2. p. 10. ISSN 1755-8794 DOI: https://doi.org/10.1186/1755-8794-2-10
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Fletcher, HA; Owiafe, P; Jeffries, D; Hill, P; Rook, GA; Zumla, A; Doherty, TM; Brookes, RH; Vacsel Study Group; (2004) Increased expression of mRNA encoding interleukin (IL)-4 and its splice variant IL-4delta2 in cells from contacts of Mycobacterium tuberculosis, in the absence of in vitro stimulation. Immunology, 112 (4). pp. 669-73. ISSN 0019-2805 DOI: https://doi.org/10.1111/j.1365-2567.2004.01922.x Full text not available from this repository.

Fletcher, HA; Pathan, AA; Berthoud, TK; Dunachie, SJ; Whelan, KT; Alder, NC; Sander, CR; Hill, AV; McShane, H; (2008) Boosting BCG vaccination with MVA85A down-regulates the immunoregulatory cytokine TGF-beta1. Vaccine, 26 (41). pp. 5269-75. ISSN 0264-410X DOI: https://doi.org/10.1016/j.vaccine.2008.07.040
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Fletcher, HA; Schrager, L; (2016) TB vaccine development and the End TB Strategy: importance and current status. Transactions of the Royal Society of Tropical Medicine and Hygiene, 110 (4). pp. 212-8. ISSN 0035-9203 DOI: https://doi.org/10.1093/trstmh/trw016
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Fletcher, HA; Snowden, MA; Landry, B; Rida, W; Satti, I; Harris, SA; Matsumiya, M; Tanner, R; O'Shea, MK; Dheenadhayalan, V; +20 more... Bogardus, L; Stockdale, L; Marsay, L; Chomka, A; Harrington-Kandt, R; Manjaly-Thomas, ZR; Naranbhai, V; Stylianou, E; Darboe, F; Penn-Nicholson, A; Nemes, E; Hatheril, M; Hussey, G; Mahomed, H; Tameris, M; McClain, JB; Evans, TG; Hanekom, WA; Scriba, TJ; McShane, H; (2016) T-cell activation is an immune correlate of risk in BCG vaccinated infants. Nature communications, 7. p. 11290. ISSN 2041-1723 DOI: https://doi.org/10.1038/ncomms11290
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Fletcher, HA; Tanner, R; Wallis, RS; Meyer, J; Manjaly, ZR; Harris, S; Satti, I; Silver, RF; Hoft, D; Kampmann, B; +6 more... Walker, KB; Dockrell, HM; Fruth, U; Barker, L; Brennan, MJ; McShane, H; (2013) Inhibition of mycobacterial growth in vitro following primary but not secondary vaccination with Mycobacterium bovis BCG. Clinical and vaccine immunology, 20 (11). pp. 1683-9. ISSN 1556-6811 DOI: https://doi.org/10.1128/CVI.00427-13 Full text not available from this repository.

Griffiths, KL; Pathan, AA; Minassian, AM; Sander, CR; Beveridge, NE; Hill, AV; Fletcher, HA; McShane, H; (2011) Th1/Th17 cell induction and corresponding reduction in ATP consumption following vaccination with the novel Mycobacterium tuberculosis vaccine MVA85A. PloS one, 6 (8). e23463. ISSN 1932-6203 DOI: https://doi.org/10.1371/journal.pone.0023463
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Griffiths, KL; Stylianou, E; Poyntz, HC; Betts, GJ; Fletcher, HA; McShane, H; (2013) Cholera toxin enhances vaccine-induced protection against Mycobacterium tuberculosis challenge in mice. PloS one, 8 (10). e78312. ISSN 1932-6203 DOI: https://doi.org/10.1371/journal.pone.0078312
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Hanekom, WA; Dockrell, HM; Ottenhoff, TH; Doherty, TM; Fletcher, H; McShane, H; Weichold, FF; Hoft, DF; Parida, SK; Fruth, UJ; (2008) Immunological Outcomes of New Tuberculosis Vaccine Trials: WHO Panel Recommendations. PLoS medicine, 5 (7). e145. ISSN 1549-1277 DOI: https://doi.org/10.1371/journal.pmed.0050145
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Harris, SA; Meyer, J; Satti, I; Marsay, L; Poulton, ID; Tanner, R; Minassian, AM; Fletcher, HA; McShane, H; (2013) Evaluation of a human BCG challenge model to assess anti-mycobacterial immunity induced by BCG and a candidate TB vaccine, MVA85A, alone and in combination. The Journal of infectious diseases. ISSN 0022-1899 DOI: https://doi.org/10.1093/infdis/jit647
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Harris, SA; Satti, I; Matsumiya, M; Stockdale, L; Chomka, A; Tanner, R; O'Shea, MK; Manjaly Thomas, ZR; Tameris, M; Mahomed, H; +4 more... Scriba, TJ; Hanekom, WA; Fletcher, HA; McShane, H; (2014) Process of Assay Selection and Optimization for the Study of Case and Control Samples from a Phase IIb Efficacy Trial of a Candidate Tuberculosis Vaccine, MVA85A. Clinical and vaccine immunology, 21 (7). pp. 1005-11. ISSN 1556-6811 DOI: https://doi.org/10.1128/CVI.00128-14
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Hawkridge, T; Scriba, TJ; Gelderbloem, S; Smit, E; Tameris, M; Moyo, S; Lang, T; Veldsman, A; Hatherill, M; Merwe, Lv; +6 more... Fletcher, HA; Mahomed, H; Hill, AV; Hanekom, WA; Hussey, GD; McShane, H; (2008) Safety and immunogenicity of a new tuberculosis vaccine, MVA85A, in healthy adults in South Africa. The Journal of infectious diseases, 198 (4). pp. 544-52. ISSN 0022-1899 DOI: https://doi.org/10.1086/590185 Full text not available from this repository.

Ibanga, HB; Brookes, RH; Hill, PC; Owiafe, PK; Fletcher, HA; Lienhardt, C; Hill, AV; Adegbola, RA; McShane, H; (2006) Early clinical trials with a new tuberculosis vaccine, MVA85A, in tuberculosis-endemic countries: issues in study design. The Lancet infectious diseases, 6 (8). pp. 522-8. ISSN 1473-3099 DOI: https://doi.org/10.1016/S1473-3099(06)70552-7 Full text not available from this repository.

Jenjaroen, K; Chumseng, S; Sumonwiriya, M; Ariyaprasert, P; Chantratita, N; Sunyakumthorn, P; Hongsuwan, M; Wuthiekanun, V; Fletcher, HA; Teparrukkul, P; +3 more... Limmathurotsakul, D; Day, NP; Dunachie, SJ; (2015) T-Cell Responses Are Associated with Survival in Acute Melioidosis Patients. PLoS neglected tropical diseases, 9 (10). e0004152. ISSN 1935-2727 DOI: https://doi.org/10.1371/journal.pntd.0004152
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Karam, F; Mbow, F; Fletcher, H; Senghor, CS; Coulibaly, KD; Lefevre, AM; Ngom Gueye, NF; Dieye, T; Sow, PS; Mboup, S; +1 more... Lienhardt, C; (2008) Sensitivity of IFN-gamma Release Assay to Detect Latent Tuberculosis Infection Is Retained in HIV-Infected Patients but Dependent on HIV/AIDS Progression. PloS one, 3 (1). e1441. ISSN 1932-6203 DOI: https://doi.org/10.1371/journal.pone.0001441
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Kasolo, F; Lishimpi, K; Chintu, C; Mwaba, P; Mudenda, V; Maswahu, D; Terunuma, H; Fletcher, H; Nunn, A; Lucas, S; +1 more... Zumla, A; (2002) Identification of Pneumocystis carinii DNA by polymerase chain reaction in necropsy lung samples from children dying of respiratory tract illnesses. The Journal of pediatrics, 140 (3). pp. 367-9. ISSN 0022-3476 DOI: https://doi.org/10.1067/mpd.2002.122468 Full text not available from this repository.

Kasprowicz, VO; Mitchell, JE; Chetty, S; Govender, P; Huang, KH; Fletcher, HA; Webster, DP; Brown, S; Kasmar, A; Millington, K; +8 more... Day, CL; Mkhwanazi, N; McClurg, C; Chonco, F; Lalvani, A; Walker, BD; Ndung'u, T; Klenerman, P; (2011) A molecular assay for sensitive detection of pathogen-specific T-cells. PloS one, 6 (8). e20606. ISSN 1932-6203 DOI: https://doi.org/10.1371/journal.pone.0020606
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Kaufmann, SH; Fletcher, HA; Guzman, CA; Ottenhoff, TH; (2015) Introduction and section summaries. Vaccine. ISSN 0264-410X DOI: https://doi.org/10.1016/j.vaccine.2015.04.078 Full text not available from this repository.

Khan, MS; Fletcher, H; London School of Hygiene and Tropical Medicine TB Centre Steerin; Coker, R; (2016) Investments in tuberculosis research - what are the gaps? BMC medicine, 14 (1). p. 123. ISSN 1741-7015 DOI: https://doi.org/10.1186/s12916-016-0644-0
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Lienhardt, C; Fielding, K; Hane, AA; Niang, A; Ndao, CT; Karam, F; Fletcher, H; Mbow, F; Gomis, JF; Diadhiou, R; +4 more... Diadhiou, R; Toupane, M; Dieye, T; Mboup, S; (2010) Evaluation of the Prognostic Value of IFN-gamma Release Assay and Tuberculin Skin Test in Household Contacts of Infectious Tuberculosis Cases in Senegal. PloS one, 5 (5). e10508. ISSN 1932-6203 DOI: https://doi.org/10.1371/journal.pone.0010508
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Marsay, L; Matsumiya, M; Tanner, R; Poyntz, H; Griffiths, KL; Stylianou, E; Marsh, PD; Williams, A; Sharpe, S; Fletcher, H; +1 more... McShane, H; (2013) Mycobacterial growth inhibition in murine splenocytes as a surrogate for protection against Mycobacterium tuberculosis (M. tb). Tuberculosis (Edinburgh, Scotland), 93 (5). pp. 551-7. ISSN 1472-9792 DOI: https://doi.org/10.1016/j.tube.2013.04.007
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Matsumiya, M; Harris, SA; Satti, I; Stockdale, L; Tanner, R; O'Shea, MK; Tameris, M; Mahomed, H; Hatherill, M; Scriba, TJ; +3 more... Hanekom, WA; McShane, H; Fletcher, HA; (2014) Inflammatory and myeloid-associated gene expression before and one day after infant vaccination with MVA85A correlates with induction of a T cell response. BMC infectious diseases, 14 (1). p. 314. ISSN 1471-2334 DOI: https://doi.org/10.1186/1471-2334-14-314
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Matsumiya, M; Satti, I; Chomka, A; Harris, SA; Stockdale, L; Meyer, J; Fletcher, HA; McShane, H; (2014) Gene expression and cytokine profile correlate with mycobacterial growth in a human BCG challenge model. The Journal of infectious diseases. ISSN 0022-1899 DOI: https://doi.org/10.1093/infdis/jiu615
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Matsumiya, M; Stylianou, E; Griffiths, K; Lang, Z; Meyer, J; Harris, SA; Rowland, R; Minassian, AM; Pathan, AA; Fletcher, H; +1 more... McShane, H; (2013) Roles for Treg expansion and HMGB1 signaling through the TLR1-2-6 axis in determining the magnitude of the antigen-specific immune response to MVA85A. PloS one, 8 (7). e67922. ISSN 1932-6203 DOI: https://doi.org/10.1371/journal.pone.0067922
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McNeill, Eileen; Stylianou, Elena; Crabtree, Mark J; Harrington-Kandt, Rachel; Kolb, Anna-Lena; Diotallevi, Marina; Hale, Ashley B; Bettencourt, Paulo; Tanner, Rachel; O'Shea, Matthew K; +7 more... Matsumiya, Magali; Lockstone, Helen; Mueller, Julius; Fletcher, Helen A; Greaves, David R; McShane, Helen; Channon, Keith M; (2018) Regulation of mycobacterial infection by macrophage Gch1 and tetrahydrobiopterin. NATURE COMMUNICATIONS, 9 (1). ISSN 2041-1723 DOI: https://doi.org/10.1038/s41467-018-07714-9
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McShane, H; Pathan, AA; Sander, CR; Goonetilleke, NP; Fletcher, HA; Hill, AV; (2005) Boosting BCG with MVA85A: the first candidate subunit vaccine for tuberculosis in clinical trials. Tuberculosis (Edinburgh, Scotland), 85 (1-2). pp. 47-52. ISSN 1472-9792 DOI: https://doi.org/10.1016/j.tube.2004.09.015 Full text not available from this repository.

McShane, H; Pathan, AA; Sander, CR; Keating, SM; Gilbert, SC; Huygen, K; Fletcher, HA; Hill, AV; (2004) Recombinant modified vaccinia virus Ankara expressing antigen 85A boosts BCG-primed and naturally acquired antimycobacterial immunity in humans. Nature medicine, 10 (11). pp. 1240-4. ISSN 1078-8956 DOI: https://doi.org/10.1038/nm1128 Full text not available from this repository.

Meyer, J; Harris, SA; Satti, I; Poulton, ID; Poyntz, HC; Tanner, R; Rowland, R; Griffiths, KL; Fletcher, HA; McShane, H; (2013) Comparing the safety and immunogenicity of a candidate TB vaccine MVA85A administered by intramuscular and intradermal delivery. Vaccine, 31 (7). pp. 1026-33. ISSN 0264-410X DOI: https://doi.org/10.1016/j.vaccine.2012.12.042 Full text not available from this repository.

Minassian, AM; Rowland, R; Beveridge, NE; Poulton, ID; Satti, I; Harris, S; Poyntz, H; Hamill, M; Griffiths, K; Sander, CR; +16 more... Ambrozak, DR; Price, DA; Hill, BJ; Casazza, JP; Douek, DC; Koup, RA; Roederer, M; Winston, A; Ross, J; Sherrard, J; Rooney, G; Williams, N; Lawrie, AM; Fletcher, HA; Pathan, AA; McShane, H; (2011) A Phase I study evaluating the safety and immunogenicity of MVA85A, a candidate TB vaccine, in HIV-infected adults. BMJ open, 1 (2). e000223. ISSN 2044-6055 DOI: https://doi.org/10.1136/bmjopen-2011-000223
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Naranbhai, V; Fletcher, HA; Tanner, R; O'Shea, MK; McShane, H; Fairfax, BP; Knight, JC; Hill, AV; (2015) Distinct Transcriptional and Anti-Mycobacterial Profiles of Peripheral Blood Monocytes Dependent on the Ratio of Monocytes: Lymphocytes. EBioMedicine, 2 (11). pp. 1619-1626. ISSN 2352-3964 DOI: https://doi.org/10.1016/j.ebiom.2015.09.027
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Naranbhai, V; Hill, AV; Abdool Karim, SS; Naidoo, K; Abdool Karim, Q; Warimwe, GM; McShane, H; Fletcher, H; (2013) Blood monocyte-lymphocyte ratios identify adults at risk of incident tuberculosis amongst patients initiating antiretroviral therapy. The Journal of infectious diseases. ISSN 0022-1899 DOI: https://doi.org/10.1093/infdis/jit494
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Naranbhai, V; Kim, S; Fletcher, H; Cotton, MF; Violari, A; Mitchell, C; Nachman, S; McSherry, G; McShane, H; Hill, A; +1 more... Madhi, SA; (2014) The association between the ratio of monocytes:lymphocytes at age 3 months and risk of tuberculosis (TB) in the first two years of life. BMC medicine, 12 (1). p. 120. ISSN 1741-7015 DOI: https://doi.org/10.1186/PREACCEPT-2435299671185919
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Naranbhai, V; Moodley, D; Chipato, T; Stranix-Chibanda, L; Nakabaiito, C; Kamateeka, M; Musoke, P; Manji, K; George, K; Emel, LM; +8 more... Richardson, P; Andrew, P; Fowler, M; Fletcher, H; Mcshane, H; Coovadia, HM; Hill, AV; for the HPTN 046 protocol team; (2014) The association between the ratio of monocytes: lymphocytes and risk of tuberculosis(TB) amongst HIV infected postpartum women. Journal of acquired immune deficiency syndromes (1999). ISSN 1525-4135 DOI: https://doi.org/10.1097/QAI.0000000000000353 Full text not available from this repository.

Pathan, AA; Minassian, AM; Sander, CR; Rowland, R; Porter, DW; Poulton, ID; Hill, AV; Fletcher, HA; McShane, H; (2012) Effect of vaccine dose on the safety and immunogenicity of a candidate TB vaccine, MVA85A, in BCG vaccinated UK adults. Vaccine, 30 (38). pp. 5616-24. ISSN 0264-410X DOI: https://doi.org/10.1016/j.vaccine.2012.06.084
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Pathan, AA; Sander, CR; Fletcher, HA; Poulton, I; Alder, NC; Beveridge, NE; Whelan, KT; Hill, AV; McShane, H; (2007) Boosting BCG with recombinant modified vaccinia ankara expressing antigen 85A: different boosting intervals and implications for efficacy trials. PloS one, 2 (10). e1052. ISSN 1932-6203 DOI: https://doi.org/10.1371/journal.pone.0001052
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Phillips, PP; Fletcher, HA; Abubakar, I; Lipman, MC; McHugh, TD; (2016) World TB Day 2016: an interview with leading experts in tuberculosis research. BMC medicine, 14 (1). p. 55. ISSN 1741-7015 DOI: https://doi.org/10.1186/s12916-016-0591-9
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Prabowo, Satria A; Zelmer, Andrea; Stockdale, Lisa; Ojha, Utkarsh; Smith, Steven G; Seifert, Karin; Fletcher, Helen A; (2019) Historical BCG vaccination combined with drug treatment enhances inhibition of mycobacterial growth ex vivo in human peripheral blood cells. SCIENTIFIC REPORTS, 9 (1). ISSN 2045-2322 DOI: https://doi.org/10.1038/s41598-019-41008-4
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Rakotosamimanana, N; Raharimanga, V; Andriamandimby, SF; Soares, JL; Doherty, TM; Ratsitorahina, M; Ramarokoto, H; Zumla, A; Huggett, J; Rook, G; +5 more... Richard, V; Gicquel, B; Rasolofo-Razanamparany, V; VACSEL/VACSIS Study Group, . (inc. Fletcher, H; ); (2010) Variation in gamma interferon responses to different infecting strains of Mycobacterium tuberculosis in acid-fast bacillus smear-positive patients and household contacts in Antananarivo, Madagascar. Clinical and vaccine immunology, 17 (7). pp. 1094-103. ISSN 1556-6811 DOI: https://doi.org/10.1128/CVI.00049-10 Full text not available from this repository.

Rhodes, SJ; Guedj, J; Fletcher, HA; Lindenstrøm, T; Scriba, TJ; Evans, TG; Knight, GM; White, RG; (2018) Using vaccine Immunostimulation/Immunodynamic modelling methods to inform vaccine dose decision-making. NPJ Vaccines, 3. p. 36. ISSN 2059-0105 DOI: https://doi.org/10.1038/s41541-018-0075-3
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Schito, M; Migliori, GB; Fletcher, HA; McNerney, R; Centis, R; D'Ambrosio, L; Bates, M; Kibiki, G; Kapata, N; Corrah, T; +6 more... Bomanji, J; Vilaplana, C; Johnson, D; Mwaba, P; Maeurer, M; Zumla, A; (2015) Perspectives on Advances in Tuberculosis Diagnostics, Drugs, and Vaccines. Clinical infectious diseases, 61 (suppl). S102-S118. ISSN 1058-4838 DOI: https://doi.org/10.1093/cid/civ609 Full text not available from this repository.

Scriba, TJ; Coussens, AK; Fletcher, HA; (2016) Human Immunology of Tuberculosis. Microbiology spectrum, 4 (5). ISSN 2165-0497 DOI: https://doi.org/10.1128/microbiolspec.TBTB2-0016-2016 Full text not available from this repository.

Scriba, TJ; Coussens, AK; Fletcher, HA; (2017) Human Immunology of Tuberculosis. Microbiology Spectrum, 5 (1). p. 24. DOI: https://doi.org/10.1128/microbiolspec.TBTB2-0016-2016 Full text not available from this repository.

Scriba, Thomas J; Coussens, Anna K; Fletcher, Helen A; (2017) Human Immunology of Tuberculosis. Microbiology Spectrum, 5 (1). ISSN 2165-0497 DOI: https://doi.org/10.1128/microbiolspec.tbtb2-0016-2016
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Sibley, Laura; Gooch, Karen; Wareham, Alice; Gray, Susan; Chancellor, Andrew; Dowall, Stuart; Bate, Simon; Marriott, Anthony; Dennis, Mike; White, Andrew D; +3 more... Marsh, Philip D; Fletcher, Helen; Sharpe, Sally; (2019) Differences in monocyte: lymphocyte ratio and Tuberculosis disease progression in genetically distinct populations of macaques. Scientific reports, 9 (1). p. 3340. ISSN 2045-2322 DOI: https://doi.org/10.1038/s41598-019-39819-6
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Smith, SG; Smits, K; Joosten, SA; van Meijgaarden, KE; Satti, I; Fletcher, HA; Caccamo, N; Dieli, F; Mascart, F; McShane, H; +3 more... Dockrell, HM; Ottenhoff, TH; TBVI TB Biomarker Working Group; (2015) Intracellular Cytokine Staining and Flow Cytometry: Considerations for Application in Clinical Trials of Novel Tuberculosis Vaccines. PloS one, 10 (9). e0138042. ISSN 1932-6203 DOI: https://doi.org/10.1371/journal.pone.0138042
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Tanner, R; Kakalacheva, K; Miller, E; Pathan, AA; Chalk, R; Sander, CR; Scriba, T; Tameris, M; Hawkridge, T; Mahomed, H; +5 more... Hussey, G; Hanekom, W; Checkley, A; McShane, H; Fletcher, HA; (2014) Serum indoleamine 2,3-dioxygenase activity is associated with reduced immunogenicity following vaccination with MVA85A. BMC infectious diseases, 14. p. 660. ISSN 1471-2334 DOI: https://doi.org/10.1186/s12879-014-0660-7
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Tanner, R; O'Shea, MK; White, AD; Müller, J; Harrington-Kandt, R; Matsumiya, M; Dennis, MJ; Parizotto, EA; Harris, S; Stylianou, E; +6 more... Naranbhai, V; Bettencourt, P; Drakesmith, H; Sharpe, S; Fletcher, HA; McShane, H; (2017) The influence of haemoglobin and iron on in vitro mycobacterial growth inhibition assays. Scientific reports, 7. p. 43478. ISSN 2045-2322 DOI: https://doi.org/10.1038/srep43478
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Vainieri, ML; Blagborough, AM; MacLean, AL; Haltalli, ML; Ruivo, N; Fletcher, HA; Stumpf, MP; Sinden, RE; Celso, CL; (2016) Systematic tracking of altered haematopoiesis during sporozoite-mediated malaria development reveals multiple response points. Open biology, 6 (6). ISSN 2046-2441 DOI: https://doi.org/10.1098/rsob.160038
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Voss, G; Casimiro, D; Neyrolles, O; Williams, A; Kaufmann, SHE; McShane, H; Hatherill, M; Fletcher, HA; (2018) Progress and challenges in TB vaccine development. F1000Research, 7. p. 199. ISSN 2046-1402 DOI: https://doi.org/10.12688/f1000research.13588.1
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Walther, M; Tongren, JE; Andrews, L; Korbel, D; King, E; Fletcher, H; Andersen, RF; Bejon, P; Thompson, F; Dunachie, SJ; +6 more... Edele, F; de Souza, JB; Sinden, RE; Gilbert, SC; Riley, EM; Hill, AV; (2005) Upregulation of TGF-beta, FOXP3, and CD4+CD25+ regulatory T cells correlates with more rapid parasite growth in human malaria infection. Immunity, 23 (3). pp. 287-96. ISSN 1074-7613 DOI: https://doi.org/10.1016/j.immuni.2005.08.006 Full text not available from this repository.

Warimwe, GM; Murungi, LM; Kamuyu, G; Nyangweso, GM; Wambua, J; Naranbhai, V; Fletcher, HA; Hill, AV; Bejon, P; Osier, FH; +1 more... Marsh, K; (2013) The ratio of monocytes to lymphocytes in peripheral blood correlates with increased susceptibility to clinical malaria in Kenyan children. PloS one, 8 (2). e57320. ISSN 1932-6203 DOI: https://doi.org/10.1371/journal.pone.0057320
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Wassie, L; Demissie, A; Aseffa, A; Abebe, M; Yamuah, L; Tilahun, H; Petros, B; Rook, G; Zumla, A; Andersen, P; +3 more... Doherty, TM; VACSEL Study Group, . (inc. Fletcher, H; ); (2008) Ex vivo cytokine mRNA levels correlate with changing clinical status of ethiopian TB patients and their contacts over time. PloS one, 3 (1). e1522. ISSN 1932-6203 DOI: https://doi.org/10.1371/journal.pone.0001522
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Whelan, KT; Pathan, AA; Sander, CR; Fletcher, HA; Poulton, I; Alder, NC; Hill, AV; McShane, H; (2009) Safety and immunogenicity of boosting BCG vaccinated subjects with BCG: comparison with boosting with a new TB vaccine, MVA85A. PloS one, 4 (6). e5934. ISSN 1932-6203 DOI: https://doi.org/10.1371/journal.pone.0005934
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Zelmer, A; Tanner, R; Stylianou, E; Damelang, T; Morris, S; Izzo, A; Williams, A; Sharpe, S; Pepponi, I; Walker, B; +4 more... Hokey, DA; McShane, H; Brennan, M; Fletcher, H; (2016) A new tool for tuberculosis vaccine screening: Ex vivo Mycobacterial Growth Inhibition Assay indicates BCG-mediated protection in a murine model of tuberculosis. BMC infectious diseases, 16. p. 412. ISSN 1471-2334 DOI: https://doi.org/10.1186/s12879-016-1751-4
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de Cassan, SC; Pathan, AA; Sander, CR; Minassian, A; Rowland, R; Hill, AV; McShane, H; Fletcher, HA; (2010) Investigating the induction of vaccine-induced Th17 and regulatory T cells in healthy, Mycobacterium bovis BCG-immunized adults vaccinated with a new tuberculosis vaccine, MVA85A. Clinical and vaccine immunology, 17 (7). pp. 1066-73. ISSN 1556-6811 DOI: https://doi.org/10.1128/CVI.00047-10 Full text not available from this repository.

Conference or Workshop Item

Griffiths, K; Stylianou, E; Poyntz, H; Betts, G; Fletcher, H; McShane, H; Beveridge, N; Minassian, A; Rowland, R; Poulton, I; +22 more... Satti, I; Harris, S; Poyntz, H; Hamill, M; Griffiths, K; Sander, C; Ambrozak, D; Price, D; Hill, B; Casazza, J; Douek, D; Koup, R; Roederer, M; Winston, A; Ross, J; Sherrad, J; Rooney, G; Williams, N; Lawrie, A; Fletcher, H; Pathan, A; McShane, H; (2011) Th1/Th17 cell induction following vaccination with the novel tuberculosis vaccine MVA85A and their role in Mycobacterium tuberculosis challenge CD4 T cell response to MVA85A vaccination against Mycobacterium tuberculosis in healthy HIV-infected adults SO IMMUNOLOGY CT Annual Congress of the British-Society-for-Immunology CY DEC 05-08, 2011 CL Liverpool, ENGLAND SP British Soc Immunol. [Conference or Workshop Item] http://researchonline.lshtm.ac.uk/id/eprint/2729027 Full text not available from this repository.

Moore, CE; Hennig, BJ; Perrett, KP; Hoe, JC; Lee, SJ; Fletcher, H; Brocklebank, D; O'Connor, D; Snape, MD; Hall, AJ; +3 more... Segal, S; Hill, AVS; Pollard, AJ; (2011) Single Nucleotide Polymorphisms in the Toll-Like Receptor 3 and CD44 Genes Are Associated with Persistence of Vaccine-Induced Immunity to the Serogroup C Meningococcal Conjugate Vaccine. [Conference or Workshop Item] https://doi.org/10.1128/CVI.05379-11 Full text not available from this repository.

Thesis

This list was generated on Wed Jun 26 09:04:57 2019 BST.