Items where Author is "Blackman, MJ"

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Number of items: 90.

2019

Blackman, Michael J; Flueck, Christian; Drought, Laura G; Jones, Andrew; Patel, Avnish; Perrin, Abigail J; Walker, Eloise M; Nofal, Stephanie; Snijders, Ambrosius P; Baker, David A; (2019) Phosphodiesterase beta is the master regulator of cAMP signalling during malaria parasite invasion. PLoS Biology. ISSN 1544-9173 DOI: https://doi.org/10.1371/journal.pbio.3000154
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Flueck, Christian; Drought, Laura G; Jones, Andrew; Patel, Avnish; Perrin, Abigail J; Walker, Eloise M; Nofal, Stephanie D; Snijders, Ambrosius P; Blackman, Michael J; Baker, David A; (2019) Phosphodiesterase beta is the master regulator of cAMP signalling during malaria parasite invasion. PLoS biology, 17 (2). e3000154-. ISSN 1544-9173 DOI: https://doi.org/10.1371/journal.pbio.3000154 Item availability may be restricted.
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Patel, Avnish; Perrin, Abigail J; Flynn, Helen R; Bisson, Claudine; Withers-Martinez, Chrislaine; Treeck, Moritz; Flueck, Christian; Nicastro, Giuseppe; Martin, Stephen R; Ramos, Andres; +4 more... Gilberger, Tim W; Snijders, Ambrosius P; Blackman, Michael J; Baker, David A; (2019) Cyclic AMP signalling controls key components of malaria parasite host cell invasion machinery. PLoS biology, 17 (5). ISSN 1544-9173 DOI: https://doi.org/10.1371/journal.pbio.3000264
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Zogota, Rimants; Kinena, Linda; Withers-Martinez, Chrislaine; Blackman, Michael J; Bobrovs, Raitis; Pantelejevs, Teodors; Kanepe-Lapsa, Iveta; Ozola, Vita; Jaudzems, Kristaps; Suna, Edgars; +1 more... Jirgensons, Aigars; (2019) Peptidomimetic plasmepsin inhibitors with potent anti-malarial activity and selectivity against cathepsin D. European Journal of Medicinal Chemistry, 163. pp. 344-352. ISSN 0223-5234 DOI: https://doi.org/10.1016/j.ejmech.2018.11.068
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2018

Boonyalai, Nonlawat; Collins, Christine R; Hackett, Fiona; Withers-Martinez, Chrislaine; Blackman, Michael J; (2018) Essentiality of Plasmodium falciparum plasmepsin V. PloS one, 13 (12). e0207621. ISSN 1932-6203 DOI: https://doi.org/10.1371/journal.pone.0207621
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Boonyalai, Nonlawat; Collins, Christine; Hackett, Fiona; Withers-Martinez, Chrislaine; Blackman, Michael; (2018) Function and essentiality of Plasmodium falciparum Plasmepsin V. BioRxiv. DOI: https://doi.org/10.1101/404798
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Deligianni, E; Silmon de Monerri, NC; McMillan, PJ; Bertuccini, L; Superti, F; Manola, M; Spanos, L; Louis, C; Blackman, MJ; Tilley, L; +1 more... Siden-Kiamos, I; (2018) Essential role of Plasmodium perforin-like protein 4 in ookinete midgut passage. PloS one, 13 (8). e0201651. ISSN 1932-6203 DOI: https://doi.org/10.1371/journal.pone.0201651
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Perrin, AJ; Collins, CR; Russell, MRG; Collinson, LM; Baker, DA; Blackman, MJ; (2018) The Actinomyosin Motor Drives Malaria Parasite Red Blood Cell Invasion but Not Egress. mBio, 9 (4). ISSN 2150-7511 DOI: https://doi.org/10.1128/mBio.00905-18
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Thomas, JA; Tan, MYS; Bisson, C; Borg, A; Umrekar, TR; Hackett, F; Hale, VL; Vizcay-Barrena, G; Fleck, RA; Snijders, AP; +2 more... Saibil, HR; Blackman, MJ; (2018) A protease cascade regulates release of the human malaria parasite Plasmodium falciparum from host red blood cells. Nature microbiology. ISSN 2058-5276 DOI: https://doi.org/10.1038/s41564-018-0111-0
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2017

Benavente, ED; de Sessions, PF; Moon, RW; Grainger, M; Holder, AA; Blackman, MJ; Roper, C; Drakeley, CJ; Pain, A; Sutherland, CJ; +3 more... Hibberd, ML; Campino, S; Clark, TG; (2017) A reference genome and methylome for the Plasmodium knowlesi A1-H.1 line. International journal for parasitology. ISSN 0020-7519 DOI: https://doi.org/10.1016/j.ijpara.2017.09.008
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Hale, VL; Watermeyer, JM; Hackett, F; Vizcay-Barrena, G; van Ooij, C; Thomas, JA; Spink, MC; Harkiolaki, M; Duke, E; Fleck, RA; +2 more... Blackman, MJ; Saibil, HR; (2017) Parasitophorous vacuole poration precedes its rupture and rapid host erythrocyte cytoskeleton collapse in Plasmodium falciparum egress. Proceedings of the National Academy of Sciences of the United States of America. ISSN 0027-8424 DOI: https://doi.org/10.1073/pnas.1619441114
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Pino, P; Caldelari, R; Mukherjee, B; Vahokoski, J; Klages, N; Maco, B; Collins, CR; Blackman, MJ; Kursula, I; Heussler, V; +2 more... Brochet, M; Soldati-Favre, D; (2017) A multistage antimalarial targets the plasmepsins IX and X essential for invasion and egress. Technical Report. American Association for the Advancement of Science. DOI: https://doi.org/10.1126/science.aaf8675
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Sherling, ES; Knuepfer, E; Brzostowski, JA; Miller, LH; Blackman, MJ; van Ooij, C; (2017) The Plasmodium falciparum rhoptry protein RhopH3 plays essential roles in host cell invasion and nutrient uptake. eLife, 6. ISSN 2050-084X DOI: https://doi.org/10.7554/eLife.23239
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2016

Hill, RJ; Ringel, A; Knuepfer, E; Moon, RW; Blackman, MJ; van Ooij, C; (2016) Regulation and essentiality of the START-domain-containing phospholipid transfer protein PFA0210c in malaria parasites. The Journal of biological chemistry, 291 (46). pp. 24280-24292. ISSN 0021-9258 DOI: https://doi.org/10.1074/jbc.M116.740506
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Jones, ML; Das, S; Belda, H; Collins, CR; Blackman, MJ; Treeck, M; (2016) A versatile strategy for rapid conditional genome engineering using loxP sites in a small synthetic intron in Plasmodium falciparum. Scientific reports, 6. p. 21800. ISSN 2045-2322 DOI: https://doi.org/10.1038/srep21800
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Moon, RW; Sharaf, H; Hastings, CH; Ho, YS; Nair, MB; Rchiad, Z; Knuepfer, E; Ramaprasad, A; Mohring, F; Amir, A; +7 more... Yusuf, NA; Hall, J; Almond, N; Lau, YL; Pain, A; Blackman, MJ; Holder, AA; (2016) Normocyte-binding protein required for human erythrocyte invasion by the zoonotic malaria parasite Plasmodium knowlesi. Proceedings of the National Academy of Sciences of the United States of America. ISSN 0027-8424 DOI: https://doi.org/10.1073/pnas.1522469113
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Thomas, JA; Collins, CR; Das, S; Hackett, F; Graindorge, A; Bell, D; Deu, E; Blackman, MJ; (2016) Development and Application of a Simple Plaque Assay for the Human Malaria Parasite Plasmodium falciparum. PloS one, 11 (6). e0157873. ISSN 1932-6203 DOI: https://doi.org/10.1371/journal.pone.0157873
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2015

Das, S; Hertrich, N; Perrin, AJ; Withers-Martinez, C; Collins, CR; Jones, ML; Watermeyer, JM; Fobes, ET; Martin, SR; Saibil, HR; +4 more... Wright, GJ; Treeck, M; Epp, C; Blackman, MJ; (2015) Processing of Plasmodium falciparum Merozoite Surface Protein MSP1 Activates a Spectrin-Binding Function Enabling Parasite Egress from RBCs. Cell host & microbe, 18 (4). pp. 433-44. ISSN 1931-3128 DOI: https://doi.org/10.1016/j.chom.2015.09.007
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Pieperhoff, MS; Pall, GS; Jiménez-Ruiz, E; Das, S; Melatti, C; Gow, M; Wong, EH; Heng, J; Müller, S; Blackman, MJ; +1 more... Meissner, M; (2015) Conditional U1 Gene Silencing in Toxoplasma gondii. PloS one, 10 (6). e0130356. ISSN 1932-6203 DOI: https://doi.org/10.1371/journal.pone.0130356
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Stallmach, R; Kavishwar, M; Withers-Martinez, C; Hackett, F; Collins, CR; Howell, SA; Yeoh, S; Knuepfer, E; Atid, AJ; Holder, AA; +1 more... Blackman, MJ; (2015) Plasmodium falciparum SERA5 plays a non-enzymatic role in the malarial asexual blood-stage lifecycle. Molecular microbiology, 96 (2). pp. 368-87. ISSN 0950-382X DOI: https://doi.org/10.1111/mmi.12941
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Watermeyer, JM; Hale, VL; Hackett, F; Clare, DK; Cutts, EE; Vakonakis, I; Fleck, RA; Blackman, MJ; Saibil, HR; (2015) A spiral scaffold underlies cytoadherent knobs in Plasmodium falciparum-infected erythrocytes. Blood, 127 (3). pp. 343-351. ISSN 0006-4971 DOI: https://doi.org/10.1182/blood-2015-10-674002
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2014

Giovani, S; Penzo, M; Brogi, S; Brindisi, M; Gemma, S; Novellino, E; Savini, L; Blackman, MJ; Campiani, G; Butini, S; (2014) Rational design of the first difluorostatone-based PfSUB1 inhibitors. Bioorganic & medicinal chemistry letters, 24 (15). pp. 3582-6. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2014.05.044 Full text not available from this repository.

Grüring, C; Moon, RW; Lim, C; Holder, AA; Blackman, MJ; Duraisingh, MT; (2014) Human red blood cell-adapted Plasmodium knowlesi parasites: a new model system for malaria research. Cellular microbiology. ISSN 1462-5814 DOI: https://doi.org/10.1111/cmi.12275 Full text not available from this repository.

Jaudzems, K; Tars, K; Maurops, G; Ivdra, N; Otikovs, M; Leitans, J; Kanepe-Lapsa, I; Domraceva, I; Mutule, I; Trapencieris, P; +2 more... Blackman, MJ; Jirgensons, A; (2014) Plasmepsin inhibitory activity and structure-guided optimization of a potent hydroxyethylamine-based antimalarial hit. ACS medicinal chemistry letters, 5 (4). pp. 373-7. ISSN 1948-5875 DOI: https://doi.org/10.1021/ml4004952 Full text not available from this repository.

Kher, SS; Penzo, M; Fulle, S; Finn, PW; Blackman, MJ; Jirgensons, A; (2014) Substrate derived peptidic α-ketoamides as inhibitors of the malarial protease PfSUB1. Bioorganic & medicinal chemistry letters. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2014.07.086
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Withers-Martinez, C; Strath, M; Hackett, F; Haire, LF; Howell, SA; Walker, PA; Christodoulou, E; Evangelos, C; Dodson, GG; Blackman, MJ; (2014) The malaria parasite egress protease SUB1 is a calcium-dependent redox switch subtilisin. Nature communications, 5. p. 3726. ISSN 2041-1723 DOI: https://doi.org/10.1038/ncomms4726
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2013

Blackman, MJ; Carruthers, VB; (2013) Recent insights into apicomplexan parasite egress provide new views to a kill. Current opinion in microbiology, 16 (4). pp. 459-64. ISSN 1369-5274 DOI: https://doi.org/10.1016/j.mib.2013.04.008 Full text not available from this repository.

Child, MA; Harris, PK; Collins, CR; Withers-Martinez, C; Yeoh, S; Blackman, MJ; (2013) Molecular determinants for subcellular trafficking of the malarial sheddase PfSUB2. Traffic (Copenhagen, Denmark), 14 (10). pp. 1053-64. ISSN 1398-9219 DOI: https://doi.org/10.1111/tra.12092
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Collins, CR; Das, S; Wong, EH; Andenmatten, N; Stallmach, R; Hackett, F; Herman, JP; Müller, S; Meissner, M; Blackman, MJ; (2013) Robust inducible Cre recombinase activity in the human malaria parasite Plasmodium falciparum enables efficient gene deletion within a single asexual erythrocytic growth cycle. Molecular microbiology, 88 (4). pp. 687-701. ISSN 0950-382X DOI: https://doi.org/10.1111/mmi.12206
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Collins, CR; Hackett, F; Strath, M; Penzo, M; Withers-Martinez, C; Baker, DA; Blackman, MJ; (2013) Malaria Parasite cGMP-dependent Protein Kinase Regulates Blood Stage Merozoite Secretory Organelle Discharge and Egress. PLoS pathogens, 9 (5). ISSN 1553-7366 DOI: https://doi.org/10.1371/journal.ppat.1003344
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Deligianni, E; Morgan, RN; Bertuccini, L; Wirth, CC; Silmon de Monerri, NC; Spanos, L; Blackman, MJ; Louis, C; Pradel, G; Siden-Kiamos, I; (2013) A perforin-like protein mediates disruption of the erythrocyte membrane during egress of Plasmodium berghei male gametocytes. Cellular microbiology, 15 (8). pp. 1438-55. ISSN 1462-5814 DOI: https://doi.org/10.1111/cmi.12131 Full text not available from this repository.

Fulle, S; Withers-Martinez, C; Blackman, MJ; Morris, GM; Finn, PW; (2013) Molecular Determinants of Binding to the Plasmodium Subtilisin-like Protease 1. Journal of chemical information and modeling, 53 (3). pp. 573-83. ISSN 1549-9596 DOI: https://doi.org/10.1021/ci300581z
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Suarez, C; Volkmann, K; Gomes, AR; Billker, O; Blackman, MJ; (2013) The malarial serine protease SUB1 plays an essential role in parasite liver stage development. PLoS pathogens, 9 (12). e1003811. ISSN 1553-7366 DOI: https://doi.org/10.1371/journal.ppat.1003811
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van Ooij, C; Withers-Martinez, C; Ringel, A; Cockcroft, S; Haldar, K; Blackman, MJ; (2013) Identification of a Plasmodium falciparum phospholipid transfer protein. The Journal of biological chemistry, 288 (44). pp. 31971-83. ISSN 0021-9258 DOI: https://doi.org/10.1074/jbc.M113.474189
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2012

Cruz, LN; Juliano, MA; Budu, A; Juliano, L; Holder, AA; Blackman, MJ; Garcia, CR; (2012) Extracellular ATP triggers proteolysis and cytosolic Ca²⁺ rise in Plasmodium berghei and Plasmodium yoelii malaria parasites. Malaria journal, 11. p. 69. ISSN 1475-2875 DOI: https://doi.org/10.1186/1475-2875-11-69
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Gemma, S; Giovani, S; Brindisi, M; Tripaldi, P; Brogi, S; Savini, L; Fiorini, I; Novellino, E; Butini, S; Campiani, G; +2 more... Penzo, M; Blackman, MJ; (2012) Quinolylhydrazones as novel inhibitors of Plasmodium falciparum serine protease PfSUB1. Bioorganic & medicinal chemistry letters, 22 (16). pp. 5317-21. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2012.06.023 Full text not available from this repository.

Moon, RW; Hall, J; Rangkuti, F; Ho, YS; Almond, N; Mitchell, GH; Pain, A; Holder, AA; Blackman, MJ; (2012) Adaptation of the genetically tractable malaria pathogen Plasmodium knowlesi to continuous culture in human erythrocytes. Proceedings of the National Academy of Sciences of the United States of America, 110 (2). pp. 531-6. ISSN 0027-8424 DOI: https://doi.org/10.1073/pnas.1216457110 Full text not available from this repository.

Ruecker, A; Shea, M; Hackett, F; Suarez, C; Hirst, EM; Milutinovic, K; Withers-Martinez, C; Blackman, MJ; (2012) Proteolytic activation of the essential parasitophorous vacuole cysteine protease SERA6 accompanies malaria parasite egress from its host erythrocyte. The Journal of biological chemistry, 287 (45). pp. 37949-63. ISSN 0021-9258 DOI: https://doi.org/10.1074/jbc.M112.400820
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Withers-Martinez, C; Suarez, C; Fulle, S; Kher, S; Penzo, M; Ebejer, JP; Koussis, K; Hackett, F; Jirgensons, A; Finn, P; +1 more... Blackman, MJ; (2012) Plasmodium subtilisin-like protease 1 (SUB1): insights into the active-site structure, specificity and function of a pan-malaria drug target. International journal for parasitology, 42 (6). pp. 597-612. ISSN 0020-7519 DOI: https://doi.org/10.1016/j.ijpara.2012.04.005
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2011

Collins, CR; Blackman, MJ; (2011) Apicomplexan AMA1 in host cell invasion: a model at the junction? Cell host & microbe, 10 (6). pp. 531-3. ISSN 1931-3128 DOI: https://doi.org/10.1016/j.chom.2011.11.006 Full text not available from this repository.

Olivieri, A; Collins, CR; Hackett, F; Withers-Martinez, C; Marshall, J; Flynn, HR; Skehel, JM; Blackman, MJ; (2011) Juxtamembrane shedding of Plasmodium falciparum AMA1 is sequence independent and essential, and helps evade invasion-inhibitory antibodies. PLoS pathogens, 7 (12). e1002448. ISSN 1553-7366 DOI: https://doi.org/10.1371/journal.ppat.1002448
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Santos, JM; Ferguson, DJ; Blackman, MJ; Soldati-Favre, D; (2011) Intramembrane cleavage of AMA1 triggers Toxoplasma to switch from an invasive to a replicative mode. Science (New York, NY), 331 (6016). pp. 473-7. ISSN 0036-8075 DOI: https://doi.org/10.1126/science.1199284 Full text not available from this repository.

Silmon de Monerri, NC; Flynn, HR; Campos, MG; Hackett, F; Koussis, K; Withers-Martinez, C; Skehel, JM; Blackman, MJ; (2011) Global identification of multiple substrates for Plasmodium falciparum SUB1, an essential malarial processing protease. Infection and immunity, 79 (3). pp. 1086-97. ISSN 0019-9567 DOI: https://doi.org/10.1128/IAI.00902-10 Full text not available from this repository.

2010

Child, MA; Epp, C; Bujard, H; Blackman, MJ; (2010) Regulated maturation of malaria merozoite surface protein-1 is essential for parasite growth. Molecular microbiology, 78 (1). pp. 187-202. ISSN 0950-382X DOI: https://doi.org/10.1111/j.1365-2958.2010.07324.x
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Friedrich, N; Santos, JM; Liu, Y; Palma, AS; Leon, E; Saouros, S; Kiso, M; Blackman, MJ; Matthews, S; Feizi, T; +1 more... Soldati-Favre, D; (2010) Members of a novel protein family containing microneme adhesive repeat domains act as sialic acid-binding lectins during host cell invasion by apicomplexan parasites. The Journal of biological chemistry, 285 (3). pp. 2064-76. ISSN 0021-9258 DOI: https://doi.org/10.1074/jbc.M109.060988 Full text not available from this repository.

2009

Collins, CR; Withers-Martinez, C; Hackett, F; Blackman, MJ; (2009) An inhibitory antibody blocks interactions between components of the malarial invasion machinery. PLoS pathogens, 5 (1). e1000273. ISSN 1553-7366 DOI: https://doi.org/10.1371/journal.ppat.1000273
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Koussis, K; Withers-Martinez, C; Yeoh, S; Child, M; Hackett, F; Knuepfer, E; Juliano, L; Woehlbier, U; Bujard, H; Blackman, MJ; (2009) A multifunctional serine protease primes the malaria parasite for red blood cell invasion. The EMBO journal, 28 (6). pp. 725-35. ISSN 0261-4189 DOI: https://doi.org/10.1038/emboj.2009.22
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Lazarou, M; Guevara Patiño, JA; Jennings, RM; McIntosh, RS; Shi, J; Howell, S; Cullen, E; Jones, T; Adame-Gallegos, JR; Chappel, JA; +4 more... McBride, JS; Blackman, MJ; Holder, AA; Pleass, RJ; (2009) Inhibition of erythrocyte invasion and Plasmodium falciparum merozoite surface protein 1 processing by human immunoglobulin G1 (IgG1) and IgG3 antibodies. Infection and immunity, 77 (12). pp. 5659-67. ISSN 0019-9567 DOI: https://doi.org/10.1128/IAI.00167-09 Full text not available from this repository.

Wanyiri, JW; Techasintana, P; O'Connor, RM; Blackman, MJ; Kim, K; Ward, HD; (2009) Role of CpSUB1, a subtilisin-like protease, in Cryptosporidium parvum infection in vitro. Eukaryotic cell, 8 (4). pp. 470-7. ISSN 1535-9778 DOI: https://doi.org/10.1128/EC.00306-08 Full text not available from this repository.

2008

Dowse, TJ; Koussis, K; Blackman, MJ; Soldati-Favre, D; (2008) Roles of proteases during invasion and egress by Plasmodium and Toxoplasma. Sub-cellular biochemistry, 47. pp. 121-39. ISSN 0306-0225 http://researchonline.lshtm.ac.uk/id/eprint/1544257 Full text not available from this repository.

Sawmynaden, K; Saouros, S; Friedrich, N; Marchant, J; Simpson, P; Bleijlevens, B; Blackman, MJ; Soldati-Favre, D; Matthews, S; (2008) Structural insights into microneme protein assembly reveal a new mode of EGF domain recognition. EMBO reports, 9 (11). pp. 1149-55. ISSN 1469-221X DOI: https://doi.org/10.1038/embor.2008.179 Full text not available from this repository.

Withers-Martinez, C; Haire, LF; Hackett, F; Walker, PA; Howell, SA; Smerdon, SJ; Dodson, GG; Blackman, MJ; (2008) Malarial EBA-175 region VI crystallographic structure reveals a KIX-like binding interface. Journal of molecular biology, 375 (3). pp. 773-81. ISSN 0022-2836 DOI: https://doi.org/10.1016/j.jmb.2007.10.071 Full text not available from this repository.

2007

Blumenschein, TM; Friedrich, N; Childs, RA; Saouros, S; Carpenter, EP; Campanero-Rhodes, MA; Simpson, P; Chai, W; Koutroukides, T; Blackman, MJ; +3 more... Feizi, T; Soldati-Favre, D; Matthews, S; (2007) Atomic resolution insight into host cell recognition by Toxoplasma gondii. The EMBO journal, 26 (11). pp. 2808-20. ISSN 0261-4189 DOI: https://doi.org/10.1038/sj.emboj.7601704 Full text not available from this repository.

Collins, CR; Withers-Martinez, C; Bentley, GA; Batchelor, AH; Thomas, AW; Blackman, MJ; (2007) Fine mapping of an epitope recognized by an invasion-inhibitory monoclonal antibody on the malaria vaccine candidate apical membrane antigen 1. The Journal of biological chemistry, 282 (10). pp. 7431-41. ISSN 0021-9258 DOI: https://doi.org/10.1074/jbc.M610562200 Full text not available from this repository.

Yeoh, S; O'Donnell, RA; Koussis, K; Dluzewski, AR; Ansell, KH; Osborne, SA; Hackett, F; Withers-Martinez, C; Mitchell, GH; Bannister, LH; +3 more... Bryans, JS; Kettleborough, CA; Blackman, MJ; (2007) Subcellular discharge of a serine protease mediates release of invasive malaria parasites from host erythrocytes. Cell, 131 (6). pp. 1072-83. ISSN 0092-8674 DOI: https://doi.org/10.1016/j.cell.2007.10.049
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2006

Montero, E; Gonzalez, LM; Rodriguez, M; Oksov, Y; Blackman, MJ; Lobo, CA; (2006) A conserved subtilisin protease identified in Babesia divergens merozoites. The Journal of biological chemistry, 281 (47). pp. 35717-26. ISSN 0021-9258 DOI: https://doi.org/10.1074/jbc.M604344200 Full text not available from this repository.

O'Donnell, RA; Hackett, F; Howell, SA; Treeck, M; Struck, N; Krnajski, Z; Withers-Martinez, C; Gilberger, TW; Blackman, MJ; (2006) Intramembrane proteolysis mediates shedding of a key adhesin during erythrocyte invasion by the malaria parasite. The Journal of cell biology, 174 (7). pp. 1023-33. ISSN 0021-9525 DOI: https://doi.org/10.1083/jcb.200604136
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2005

Carruthers, VB; Blackman, MJ; (2005) A new release on life: emerging concepts in proteolysis and parasite invasion. Molecular microbiology, 55 (6). pp. 1617-30. ISSN 0950-382X DOI: https://doi.org/10.1111/j.1365-2958.2005.04483.x Full text not available from this repository.

Chesne-Seck, ML; Pizarro, JC; Vulliez-Le Normand, B; Collins, CR; Blackman, MJ; Faber, BW; Remarque, EJ; Kocken, CH; Thomas, AW; Bentley, GA; (2005) Structural comparison of apical membrane antigen 1 orthologues and paralogues in apicomplexan parasites. Molecular and biochemical parasitology, 144 (1). pp. 55-67. ISSN 0166-6851 DOI: https://doi.org/10.1016/j.molbiopara.2005.07.007 Full text not available from this repository.

Ersmark, K; Nervall, M; Hamelink, E; Janka, LK; Clemente, JC; Dunn, BM; Blackman, MJ; Samuelsson, B; Aqvist, J; Hallberg, A; (2005) Synthesis of malarial plasmepsin inhibitors and prediction of binding modes by molecular dynamics simulations. Journal of medicinal chemistry, 48 (19). pp. 6090-106. ISSN 0022-2623 DOI: https://doi.org/10.1021/jm050463l Full text not available from this repository.

Harris, PK; Yeoh, S; Dluzewski, AR; O'Donnell, RA; Withers-Martinez, C; Hackett, F; Bannister, LH; Mitchell, GH; Blackman, MJ; (2005) Molecular identification of a malaria merozoite surface sheddase. PLoS pathogens, 1 (3). pp. 241-51. ISSN 1553-7366 DOI: https://doi.org/10.1371/journal.ppat.0010029
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Howell, SA; Hackett, F; Jongco, AM; Withers-Martinez, C; Kim, K; Carruthers, VB; Blackman, MJ; (2005) Distinct mechanisms govern proteolytic shedding of a key invasion protein in apicomplexan pathogens. Molecular microbiology, 57 (5). pp. 1342-56. ISSN 0950-382X DOI: https://doi.org/10.1111/j.1365-2958.2005.04772.x Full text not available from this repository.

Jean, L; Withers-Martinez, C; Hackett, F; Blackman, MJ; (2005) Unique insertions within Plasmodium falciparum subtilisin-like protease-1 are crucial for enzyme maturation and activity. Molecular and biochemical parasitology, 144 (2). pp. 187-97. ISSN 0166-6851 DOI: https://doi.org/10.1016/j.molbiopara.2005.07.008 Full text not available from this repository.

Johansson, PO; Lindberg, J; Blackman, MJ; Kvarnström, I; Vrang, L; Hamelink, E; Hallberg, A; Rosenquist, A; Samuelsson, B; (2005) Design and synthesis of potent inhibitors of plasmepsin I and II: X-ray crystal structure of inhibitor in complex with plasmepsin II. Journal of medicinal chemistry, 48 (13). pp. 4400-9. ISSN 0022-2623 DOI: https://doi.org/10.1021/jm040884n Full text not available from this repository.

O'Donnell, RA; Blackman, MJ; (2005) The role of malaria merozoite proteases in red blood cell invasion. Current opinion in microbiology, 8 (4). pp. 422-7. ISSN 1369-5274 DOI: https://doi.org/10.1016/j.mib.2005.06.018 Full text not available from this repository.

Pizarro, JC; Vulliez-Le Normand, B; Chesne-Seck, ML; Collins, CR; Withers-Martinez, C; Hackett, F; Blackman, MJ; Faber, BW; Remarque, EJ; Kocken, CH; +2 more... Thomas, AW; Bentley, GA; (2005) Crystal structure of the malaria vaccine candidate apical membrane antigen 1. Science (New York, NY), 308 (5720). pp. 408-11. ISSN 0036-8075 DOI: https://doi.org/10.1126/science.1107449 Full text not available from this repository.

Polson, HE; Blackman, MJ; (2005) A role for poly(dA)poly(dT) tracts in directing activity of the Plasmodium falciparum calmodulin gene promoter. Molecular and biochemical parasitology, 141 (2). pp. 179-89. ISSN 0166-6851 DOI: https://doi.org/10.1016/j.molbiopara.2005.02.008 Full text not available from this repository.

2004

Blackman, MJ; (2004) Proteases in host cell invasion by the malaria parasite. Cellular microbiology, 6 (10). pp. 893-903. ISSN 1462-5814 DOI: https://doi.org/10.1111/j.1462-5822.2004.00437.x Full text not available from this repository.

Ersmark, K; Feierberg, I; Bjelic, S; Hamelink, E; Hackett, F; Blackman, MJ; Hultén, J; Samuelsson, B; Aqvist, J; Hallberg, A; (2004) Potent inhibitors of the Plasmodium falciparum enzymes plasmepsin I and II devoid of cathepsin D inhibitory activity. Journal of medicinal chemistry, 47 (1). pp. 110-22. ISSN 0022-2623 DOI: https://doi.org/10.1021/jm030933g Full text not available from this repository.

Johansson, PO; Chen, Y; Belfrage, AK; Blackman, MJ; Kvarnström, I; Jansson, K; Vrang, L; Hamelink, E; Hallberg, A; Rosenquist, A; +1 more... Samuelsson, B; (2004) Design and synthesis of potent inhibitors of the malaria aspartyl proteases plasmepsin I and II. Use of solid-phase synthesis to explore novel statine motifs. Journal of medicinal chemistry, 47 (13). pp. 3353-66. ISSN 0022-2623 DOI: https://doi.org/10.1021/jm031106i Full text not available from this repository.

Silvie, O; Franetich, JF; Charrin, S; Mueller, MS; Siau, A; Bodescot, M; Rubinstein, E; Hannoun, L; Charoenvit, Y; Kocken, CH; +7 more... Thomas, AW; Van Gemert, GJ; Sauerwein, RW; Blackman, MJ; Anders, RF; Pluschke, G; Mazier, D; (2004) A role for apical membrane antigen 1 during invasion of hepatocytes by Plasmodium falciparum sporozoites. The Journal of biological chemistry, 279 (10). pp. 9490-6. ISSN 0021-9258 DOI: https://doi.org/10.1074/jbc.M311331200 Full text not available from this repository.

Withers-Martinez, C; Jean, L; Blackman, MJ; (2004) Subtilisin-like proteases of the malaria parasite. Molecular microbiology, 53 (1). pp. 55-63. ISSN 0950-382X DOI: https://doi.org/10.1111/j.1365-2958.2004.04144.x Full text not available from this repository.

Zhou, XW; Blackman, MJ; Howell, SA; Carruthers, VB; (2004) Proteomic analysis of cleavage events reveals a dynamic two-step mechanism for proteolysis of a key parasite adhesive complex. Molecular & cellular proteomics, 3 (6). pp. 565-76. ISSN 1535-9476 DOI: https://doi.org/10.1074/mcp.M300123-MCP200 Full text not available from this repository.

2003

Bannister, LH; Hopkins, JM; Dluzewski, AR; Margos, G; Williams, IT; Blackman, MJ; Kocken, CH; Thomas, AW; Mitchell, GH; (2003) Plasmodium falciparum apical membrane antigen 1 (PfAMA-1) is translocated within micronemes along subpellicular microtubules during merozoite development. Journal of cell science, 116 (Pt 18). pp. 3825-34. ISSN 0021-9533 DOI: https://doi.org/10.1242/jcs.00665 Full text not available from this repository.

Blackman, MJ; (2003) RNAi in protozoan parasites: what hope for the Apicomplexa? Protist, 154 (2). pp. 177-80. ISSN 1434-4610 DOI: https://doi.org/10.1078/143446103322166482 Full text not available from this repository.

Fleck, SL; Birdsall, B; Babon, J; Dluzewski, AR; Martin, SR; Morgan, WD; Angov, E; Kettleborough, CA; Feeney, J; Blackman, MJ; +1 more... Holder, AA; (2003) Suramin and suramin analogues inhibit merozoite surface protein-1 secondary processing and erythrocyte invasion by the malaria parasite Plasmodium falciparum. The Journal of biological chemistry, 278 (48). pp. 47670-7. ISSN 0021-9258 DOI: https://doi.org/10.1074/jbc.M306603200 Full text not available from this repository.

Howell, SA; Well, I; Fleck, SL; Kettleborough, C; Collins, CR; Blackman, MJ; (2003) A single malaria merozoite serine protease mediates shedding of multiple surface proteins by juxtamembrane cleavage. The Journal of biological chemistry, 278 (26). pp. 23890-8. ISSN 0021-9258 DOI: https://doi.org/10.1074/jbc.M302160200 Full text not available from this repository.

Jean, L; Hackett, F; Martin, SR; Blackman, MJ; (2003) Functional characterization of the propeptide of Plasmodium falciparum subtilisin-like protease-1. The Journal of biological chemistry, 278 (31). pp. 28572-9. ISSN 0021-9258 DOI: https://doi.org/10.1074/jbc.M303827200 Full text not available from this repository.

Miller, SA; Thathy, V; Ajioka, JW; Blackman, MJ; Kim, K; (2003) TgSUB2 is a Toxoplasma gondii rhoptry organelle processing proteinase. Molecular microbiology, 49 (4). pp. 883-94. ISSN 0950-382X DOI: https://doi.org/10.1046/j.1365-2958.2003.03604.x Full text not available from this repository.

2002

Blackman, MJ; Corrie, JE; Croney, JC; Kelly, G; Eccleston, JF; Jameson, DM; (2002) Structural and biochemical characterization of a fluorogenic rhodamine-labeled malarial protease substrate. Biochemistry, 41 (40). pp. 12244-52. ISSN 0006-2960 DOI: https://doi.org/10.1021/bi0263661 Full text not available from this repository.

Kocken, CH; Withers-Martinez, C; Dubbeld, MA; van der Wel, A; Hackett, F; Valderrama, A; Blackman, MJ; Thomas, AW; (2002) High-level expression of the malaria blood-stage vaccine candidate Plasmodium falciparum apical membrane antigen 1 and induction of antibodies that inhibit erythrocyte invasion. Infection and immunity, 70 (8). pp. 4471-6. ISSN 0019-9567 DOI: https://doi.org/10.1128/IAI.70.8.4471-4476.2002 Full text not available from this repository.

Withers-Martinez, C; Saldanha, JW; Ely, B; Hackett, F; O'Connor, T; Blackman, MJ; (2002) Expression of recombinant Plasmodium falciparum subtilisin-like protease-1 in insect cells. Characterization, comparison with the parasite protease, and homology modeling. The Journal of biological chemistry, 277 (33). pp. 29698-709. ISSN 0021-9258 DOI: https://doi.org/10.1074/jbc.M203088200 Full text not available from this repository.

2001

Blackman, MJ; Bannister, LH; (2001) Apical organelles of Apicomplexa: biology and isolation by subcellular fractionation. Molecular and biochemical parasitology, 117 (1). pp. 11-25. ISSN 0166-6851 DOI: https://doi.org/10.1016/S0166-6851(01)00328-0 Full text not available from this repository.

Howell, SA; Withers-Martinez, C; Kocken, CH; Thomas, AW; Blackman, MJ; (2001) Proteolytic processing and primary structure of Plasmodium falciparum apical membrane antigen-1. The Journal of biological chemistry, 276 (33). pp. 31311-20. ISSN 0021-9258 DOI: https://doi.org/10.1074/jbc.M103076200 Full text not available from this repository.

Miller, SA; Binder, EM; Blackman, MJ; Carruthers, VB; Kim, K; (2001) A conserved subtilisin-like protein TgSUB1 in microneme organelles of Toxoplasma gondii. The Journal of biological chemistry, 276 (48). pp. 45341-8. ISSN 0021-9258 DOI: https://doi.org/10.1074/jbc.M106665200 Full text not available from this repository.

This list was generated on Mon Jun 24 11:46:00 2019 BST.