Potent bicyclic inhibitors of malarial cGMP-dependent protein kinase: approaches to combining improvements in cell potency, selectivity and structural novelty.

Large, Jonathan M; Birchall, Kristian; Bouloc, Nathalie S; Merritt, Andy T; Smiljanic-Hurley, Ela; Tsagris, Denise J; Wheldon, Mary C; Ansell, Keith H; Coombs, Peter J; Kettleborough, Catherine A; +5 more... Whalley, David; Stewart, Lindsay B; Bowyer, Paul W; Baker, David A; Osborne, Simon A; (2019) Potent bicyclic inhibitors of malarial cGMP-dependent protein kinase: approaches to combining improvements in cell potency, selectivity and structural novelty. Bioorganic & medicinal chemistry letters, 29 (19). 126610-. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2019.08.014

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