The impact of insecticide-treated school uniforms on dengue infections in school-aged children: study protocol for a randomised controlled trial in Thailand.
Wilder-Smith, Annelies;
Byass, Peter;
Olanratmanee, Phanthip;
Maskhao, Pongsri;
Sringernyuang, Luechai;
Logan, James G;
Lindsay, Steve W;
Banks, Sarah;
Gubler, Duane;
Louis, Valérie R;
+2 more...Tozan, Yesim;
Kittayapong, Pattamaporn;
(2012)
The impact of insecticide-treated school uniforms on dengue infections in school-aged children: study protocol for a randomised controlled trial in Thailand.
TRIALS, 13 (1).
212-.
ISSN 1745-6215
DOI: https://doi.org/10.1186/1745-6215-13-212
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BACKGROUND: There is an urgent need to protect children against dengue since this age group is particularly sensitive to the disease. Since dengue vectors are active mainly during the day, a potential target for control should be schools where children spend a considerable amount of their day. School uniforms are the cultural norm in most developing countries, worn throughout the day. We hypothesise that insecticide-treated school uniforms will reduce the incidence of dengue infection in school-aged children. Our objective is to determine the impact of impregnated school uniforms on dengue incidence. METHODS: A randomised controlled trial will be conducted in eastern Thailand in a group of schools with approximately 2,000 students aged 7-18 years. Pre-fabricated school uniforms will be commercially treated to ensure consistent, high-quality insecticide impregnation with permethrin. A double-blind, randomised, crossover trial at the school level will cover two dengue transmission seasons. DISCUSSION: Practical issues and plans concerning intervention implementation, evaluation, analysing and interpreting the data, and possible policy implications arising from the trial are discussed. TRIAL REGISTRATION: clinicaltrial.gov. REGISTRATION NUMBER: NCT01563640.