Catheter-based renal denervation in patients with uncontrolled hypertension in the absence of antihypertensive medications (SPYRAL HTN-OFF MED): a randomised, sham-controlled, proof-of-concept trial.

Townsend, RR; Mahfoud, F; Kandzari, DE; Kario, K; Pocock, S; Weber, MA; Ewen, S; Tsioufis, K; Tousoulis, D; Sharp, ASP; +73 more... Watkinson, AF; Schmieder, RE; Schmid, A; Choi, JW; East, C; Walton, A; Hopper, I; Cohen, DL; Wilensky, R; Lee, DP; Ma, A; Devireddy, CM; Lea, JP; Lurz, PC; Fengler, K; Davies, J; Chapman, N; Cohen, SA; DeBruin, V; Fahy, M; Jones, DE; Rothman, M; Böhm, M; SPYRAL HTN-OFF MED trial investigators*; , COLLABORATORS; Aoki, J; Batson, B; Böhm, M; Choi, JW; Cohen, DL; Dangas, G; David, S; Davies, J; Devireddy, CM; Kandzari, D; Kario, K; Lee, DP; Lurz, PC; Patel, M; Patel, K; Schmieder, RE; Sharp, ASP; Singh, J; Tsioufis, K; Walton, A; Weber, T; Weil, J; Zeller, T; Ziada, K; Tanabe, K; Wilkins, R; Mahfoud, F; East, C; Wilensky, R; Contreras, J; Steigerwalt, S; Chapman, N; Lea, JP; Reedus, D; Hoshide, S; Ma, A; Fengler, K; Svetkey, L; Rao, A; Schmid, A; Watkinson, AF; Brown, A; Tousoulis, D; Hopper, I; Suppan, M; Agdirlioglu, T; Noory, E; Chasen, C; (2017) Catheter-based renal denervation in patients with uncontrolled hypertension in the absence of antihypertensive medications (SPYRAL HTN-OFF MED): a randomised, sham-controlled, proof-of-concept trial. Lancet. ISSN 0140-6736 DOI: https://doi.org/10.1016/S0140-6736(17)32281-X

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