In Vitro Susceptibility to Closthioamide among Clinical and Reference Strains of Neisseria gonorrhoeae.
Miari, Victoria F;
Solanki, Priya;
Hleba, Yonek;
Stabler, Richard A;
Heap, John T;
(2017)
In Vitro Susceptibility to Closthioamide among Clinical and Reference Strains of Neisseria gonorrhoeae.
Antimicrobial agents and chemotherapy, 61 (10).
e00929-17.
ISSN 0066-4804
DOI: https://doi.org/10.1128/AAC.00929-17
Permanent Identifier
Use this Digital Object Identifier when citing or linking to this resource.
Neisseria gonorrhoeae is one of the leading antimicrobial resistance threats worldwide. This study determined the MICs of closthioamide to be 0.008 to 0.5 mg/liter for clinical N. gonorrhoeae strains and related species. Cross-resistance with existing antimicrobial resistance was not detected, indicating that closthioamide could be used to treat drug-resistant N. gonorrhoeae.