KEAP1-modifying small molecule reveals muted NRF2 signaling responses in neural stem cells from Huntington's disease patients.

Quinti, Luisa; Dayalan Naidu, Sharadha; Träger, Ulrike; Chen, Xiqun; Kegel-Gleason, Kimberly; Llères, David; Connolly, Colúm; Chopra, Vanita; Low, Cho; Moniot, Sébastien; +29 more... Sapp, Ellen; Tousley, Adelaide R; Vodicka, Petr; Van Kanegan, Michael J; Kaltenbach, Linda S; Crawford, Lisa A; Fuszard, Matthew; Higgins, Maureen; Miller, James RC; Farmer, Ruth E; Potluri, Vijay; Samajdar, Susanta; Meisel, Lisa; Zhang, Ningzhe; Snyder, Andrew; Stein, Ross; Hersch, Steven M; Ellerby, Lisa M; Weerapana, Eranthie; Schwarzschild, Michael A; Steegborn, Clemens; Leavitt, Blair R; Degterev, Alexei; Tabrizi, Sarah J; Lo, Donald C; DiFiglia, Marian; Thompson, Leslie M; Dinkova-Kostova, Albena T; Kazantsev, Aleksey G; (2017) KEAP1-modifying small molecule reveals muted NRF2 signaling responses in neural stem cells from Huntington's disease patients. Proceedings of the National Academy of Sciences of the United States of America, 114 (23). E4676-E4685. ISSN 0027-8424 DOI: https://doi.org/10.1073/pnas.1614943114

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