Investigation of low 5-year relative survival for breast cancer in a London cancer network.

Davies, EA; Linklater, KM; Coupland, VH; Renshaw, C; Toy, J; Park, R; Petit, J; Housden, C; Møller, H; (2010) Investigation of low 5-year relative survival for breast cancer in a London cancer network. British journal of cancer, 103 (7). pp. 1076-1080. ISSN 0007-0920 DOI: https://doi.org/10.1038/sj.bjc.6605857

Abstract

BACKGROUND: Breast cancer 5-year relative survival is low in the North East London Cancer Network (NELCN). METHODS: We compared breast cancer that was diagnosed during 2001-2005 with that in the rest of London. RESULTS: North East London Cancer Network women more often lived in socioeconomic quintile 5 (42 vs 21%) and presented with advanced disease (11 vs 7%). Cox regression analysis showed the survival difference (hazard ratio: 1.27, 95% confidence interval (CI): 1.15-1.41) reduced to 1.00 (95% CI: 0.89-1.11) after adjustment for age, stage, socioeconomic deprivation, ethnicity and treatment. Major drivers were stage and deprivation. Excess mortality was in the first year. CONCLUSION: Late diagnosis occurs in NELCN.