Mice deficient for both corticotropin-releasing factor receptor 1 (CRFR1) and CRFR2 have an impaired stress response and display sexually dichotomous anxiety-like behavior.

Bale, Tracy L; Picetti, Roberto; Contarino, Angelo; Koob, George F; Vale, Wylie W; Lee, Kuo-Fen; (2002) Mice deficient for both corticotropin-releasing factor receptor 1 (CRFR1) and CRFR2 have an impaired stress response and display sexually dichotomous anxiety-like behavior. The Journal of neuroscience, 22 (1). pp. 193-199. ISSN 0270-6474 DOI: https://doi.org/10.1523/JNEUROSCI.22-01-00193.2002

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Abstract

Item Type Article
Keywords Adrenal Glands/pathology, Adrenocorticotropic Hormone/blood, Animals, Anxiety/*genetics/physiopathology, Behavior, Animal/*physiology, Brain/metabolism, Corticosterone/blood, Corticotropin-Releasing Hormone/genetics/metabolism, Exploratory Behavior, Female, Gene Expression Regulation, Genotype, Hypothalamo-Hypophyseal System/cytology/physiopathology, Male, Mice, Mice, Knockout, Mothers, Motor Activity/genetics, Phenotype, Pituitary-Adrenal System/pathology/physiopathology, RNA, Messenger/metabolism, Receptors, Corticotropin-Releasing Hormone/*deficiency/genetics/metabolism, Sex Factors, Stress, Physiological/*genetics/physiopathology, Urocortins, Vasopressins/genetics/metabolism, Adrenal Glands, pathology, Adrenocorticotropic Hormone, blood, Animals, Anxiety, genetics, physiopathology, Behavior, Animal, physiology, Brain, metabolism, Corticosterone, blood, Corticotropin-Releasing Hormone, genetics, metabolism, Exploratory Behavior, Female, Gene Expression Regulation, Genotype, Hypothalamo-Hypophyseal System, cytology, physiopathology, Male, Mice, Mice, Knockout, Mothers, Motor Activity, genetics, Phenotype, Pituitary-Adrenal System, pathology, physiopathology, RNA, Messenger, metabolism, Receptors, Corticotropin-Releasing Hormone, deficiency, genetics, metabolism, Sex Factors, Stress, Physiological, genetics, physiopathology, Urocortins, Vasopressins, genetics, metabolism
Faculty and Department Faculty of Epidemiology and Population Health > Dept of Population Health (2012- )
PubMed ID 11756502
ISI 172905700027

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