Garmory, Helen S;
Perkins, Stuart D;
Phillpotts, Robert J;
Titball, Richard W;
(2005)
DNA vaccines for biodefence.
Advanced drug delivery reviews, 57 (9).
pp. 1343-1361.
ISSN 0169-409X
DOI: https://doi.org/10.1016/j.addr.2005.01.013
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The advantages associated with DNA vaccines include the speed with which they may be constructed and produced at large-scale, the ability to produce a broad spectrum of immune responses, and the ability for delivery using non-invasive means. In addition, DNA vaccines may be manipulated to express multiple antigens and may be tailored for the induction of appropriate immune responses. These advantages make DNA vaccination a promising approach for the development of vaccines for biodefence. In this review, the potential of DNA vaccines for biodefence is discussed.