The preterm birth syndrome: a prototype phenotypic classification.


Villar, J; Papageorghiou, AT; Knight, HE; Gravett, MG; Iams, J; Waller, SA; Kramer, M; Culhane, JF; Barros, FC; Conde-Agudelo, A; Bhutta, ZA; Goldenberg, RL; (2012) The preterm birth syndrome: a prototype phenotypic classification. American journal of obstetrics and gynecology, 206 (2). pp. 119-23. ISSN 0002-9378 DOI: https://doi.org/10.1016/j.ajog.2011.10.866

Full text not available from this repository.

Abstract

Preterm birth is a syndrome with many causes and phenotypes. We propose a classification that is based on clinical phenotypes that are defined by ≥ 1 characteristics of the mother, the fetus, the placenta, the signs of parturition, and the pathway to delivery. Risk factors and mode of delivery are not included. There are 5 components in a preterm birth phenotype: (1) maternal conditions that are present before presentation for delivery, (2) fetal conditions that are present before presentation for delivery, (3) placental pathologic conditions, (4) signs of the initiation of parturition, and (5) the pathway to delivery. This system does not force any preterm birth into a predefined phenotype and allows all relevant conditions to become part of the phenotype. Needed data can be collected from the medical records to classify every preterm birth. The classification system will improve understanding of the cause and improve surveillance across populations.

Item Type: Article
Faculty and Department: Faculty of Public Health and Policy > Dept of Health Services Research and Policy
PubMed ID: 22177191
Web of Science ID: 299836800013
URI: http://researchonline.lshtm.ac.uk/id/eprint/945326

Statistics


Download activity - last 12 months
Downloads since deposit
0Downloads
257Hits
Accesses by country - last 12 months
Accesses by referrer - last 12 months
Impact and interest
Additional statistics for this record are available via IRStats2

Actions (login required)

Edit Item Edit Item