Plasma concentrations of carotenoids and vitamin C are better correlated with dietary intake in normal weight than overweight and obese elderly subjects


Vioque, J; Weinbrenner, T; Asensio, L; Castello, A; Young, IS; Fletcher, A; (2007) Plasma concentrations of carotenoids and vitamin C are better correlated with dietary intake in normal weight than overweight and obese elderly subjects. The British journal of nutrition, 97 (5). pp. 977-986. ISSN 0007-1145 DOI: https://doi.org/10.1017/S0007114507659017

[img]
Preview
Text - Published Version
License: Copyright the publishers

Download (112kB) | Preview

Abstract

Carotenoid and vitamin C intakes, assessed by FFQ, have been positively associated with plasma concentrations in different populations. However, the influence of BMI on these associations has not been explored in detail. We explored in a cross-sectional study the relation between dietary carotenoid and vitamin C intakes, using a 135-item FFQ, with their plasma concentrations by BMI categories in 252 men and 293 women, 65 years and older. For men and women combined, significant (P<0.05) Pearson correlations were observed between energy-adjusted dietary intakes and plasma concentrations (carotenoids adjusted for cholesterol) for: a-carotene 0.21, beta-carotene 0.19, lycopene 0.18, (beta-cryptoxanthin 0.20 and vitamin C 0.36. Multiple linear regression analyses showed that the intake of carotenoids and vitamin C were significant predictors of their respective plasma concentration (P<0.01), and that BMI was inversely associated with plasma concentration of carotenoids (P <= 0.01) but not with plasma vitamin C. In addition, we observed significant interactions between BMI and the intakes of a-carotene and lutein + zeaxanthin, and to a lower extent beta-carotene, suggesting that these intakes in subjects with high BMI were not good predictors of their plasma concentration. The present data suggest that plasma carotenoids and vitamin C may be good markers of dietary intake in elderly subjects, but not so for a-carotene, beta-carotene and lutein + zeaxanthin in obese subjects.

Item Type: Article
Keywords: carotenoids, vitamin C, food frequency questionnaire, plasma, concentrations, AGE-RELATED MACULOPATHY, FOOD FREQUENCY QUESTIONNAIRE, BODY-MASS-INDEX, BETA-CAROTENE, MACULAR DEGENERATION, SERUM CONCENTRATIONS, OXIDATIVE, STRESS, ALPHA-TOCOPHEROL, CHRONIC DISEASE, FRUITS
Faculty and Department: Faculty of Epidemiology and Population Health > Dept of Non-Communicable Disease Epidemiology
PubMed ID: 17408529
Web of Science ID: 246523200023
URI: http://researchonline.lshtm.ac.uk/id/eprint/9402

Statistics


Download activity - last 12 months
Downloads since deposit
249Downloads
306Hits
Accesses by country - last 12 months
Accesses by referrer - last 12 months
Impact and interest
Additional statistics for this record are available via IRStats2

Actions (login required)

Edit Item Edit Item