Job Strain and Risk of Breast Cancer.


Kuper, H; Yang, L; Theorell, T; Weiderpass, E; (2007) Job Strain and Risk of Breast Cancer. Epidemiology (Cambridge, Mass), 18 (6). pp. 764-8. ISSN 1044-3983 DOI: https://doi.org/10.1097/EDE.0b013e318142c534

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Abstract

BACKGROUND: Cohort studies investigating the association between stress and breast cancer have shown highly inconsistent results. METHODS: The Women's Lifestyle and Health Cohort Study included 36,332 Swedish women age 30-50 years who were employed at baseline (1991-1992). Participants were followed through December 2004 using linkages to national registries. A total of 767 women were diagnosed with breast cancer during follow-up. RESULTS: Among women working full-time, low job control and high job demands were weakly associated with breast cancer risk (hazard ratios of 1.2; 95% CI = 1.0-1.5). Women with both low job control and high job demands ("job strain") had higher risk of breast cancer than women with high job control and low demands ("low strain") (1.2; 0.9-1.6). Multivariate adjustment slightly strengthened the association between breast cancer and job strain (1.4; 1.1-1.9), whereas the associations with control and demands were unchanged. Work characteristics were unrelated to breast cancer risk among women working part-time. DISCUSSION: There was a small increased risk of breast cancer among women in full-time employment who experienced job strain, but not among part-time workers.

Item Type: Article
Faculty and Department: Faculty of Infectious and Tropical Diseases > Dept of Clinical Research
Research Centre: The International Centre for Evidence in Disability
International Centre for Eye Health
Centre for Global Non-Communicable Diseases (NCDs)
PubMed ID: 17786125
Web of Science ID: 262285900018
URI: http://researchonline.lshtm.ac.uk/id/eprint/9186

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