Septic shock and multi-organ failure in HIV infection-'sepsis tuberculosa gravissima'

Ferrand, RA; Herman, J; Elgalib, A; Cartledge, J; Miller, RF; (2006) Septic shock and multi-organ failure in HIV infection-'sepsis tuberculosa gravissima'. International journal of STD & AIDS, 17 (8). pp. 562-4. ISSN 0956-4624 DOI:

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A profoundly immunosuppressed HIV-infected man developed sepsis syndrome with multi-organ failure. A septic screen failed to identify a bacterial or fungal cause and despite empirical treatment for these pathogens the patient remained unwell. Investigations revealed disseminated tuberculosis. With specific anti-tuberculosis therapy the patient rapidly recovered. Although most cases of sepsis syndrome in HIV-infected patients are due to bacteria, tuberculosis should be added to the differential diagnosis of this presentation.

Item Type: Article
Keywords: AIDS-Related Opportunistic Infections/microbiology, *Hiv, HIV Infections/immunology/*microbiology, Humans, Male, Middle Aged, Multiple Organ Failure/*microbiology/*virology, Mycobacterium tuberculosis/isolation & purification, Shock, Septic/*microbiology/*virology, Tuberculosis, Pulmonary/microbiology/*virology, AIDS-Related Opportunistic Infections, microbiology, HIV, HIV Infections, immunology, microbiology, Humans, Male, Middle Aged, Multiple Organ Failure, microbiology, virology, Mycobacterium tuberculosis, isolation & purification, Shock, Septic, microbiology, virology, Tuberculosis, Pulmonary, microbiology, virology
Faculty and Department: Faculty of Infectious and Tropical Diseases > Dept of Clinical Research
PubMed ID: 16925907
Web of Science ID: 240099700015


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