Hepatitis A surveillance in England--how many cases are not reported and does it really matter?

Matin, N; Grant, A; Granerod, J; Crowcroft, N; (2006) Hepatitis A surveillance in England--how many cases are not reported and does it really matter? Epidemiology and infection, 134 (6). pp. 1299-302. ISSN 0950-2688 DOI: https://doi.org/10.1017/S0950268806006194

Text - Published Version
License: Copyright the publishers

Download (78kB) | Preview


Underreporting of hepatitis A infection in England may be high and a number of outbreaks have occurred undetected by routine surveillance. We evaluated surveillance of hepatitis A cases by employing capture-recapture analysis on data from two distinct outbreaks of hepatitis A. The overall reporting of cases of hepatitis A was 81.7% (95% CI 55.3-95) in the first outbreak in North East England and reporting through Lab Base was 65.7% (95% CI 42.8-76.4). In the second outbreak in the East Midlands the overall reporting of hepatitis A cases was 27.8% (95% CI 19-38.7) and through Lab Base 16.6% (95% CI 11.4-23.1). Underreporting of hepatitis A cases is high. Public health interventions exist to prevent and control outbreaks of hepatitis A. The lack of reliable data on incidence and prevalence hampers effective public health management of this disease.

Item Type: Article
Keywords: Disease Notification/*standards, Disease Outbreaks, England/epidemiology, Health Services Research, Hepatitis A/*epidemiology/transmission, Humans, Linear Models, *Population Surveillance, Public Health Informatics/*standards, Disease Notification, standards, Disease Outbreaks, England, epidemiology, Health Services Research, Hepatitis A, epidemiology, transmission, Humans, Linear Models, Population Surveillance, Public Health Informatics, standards
Faculty and Department: Faculty of Epidemiology and Population Health > Dept of Infectious Disease Epidemiology
Research Centre: Vaccine Centre
PubMed ID: 16684404
Web of Science ID: 242231800022
URI: http://researchonline.lshtm.ac.uk/id/eprint/8978


Download activity - last 12 months
Downloads since deposit
Accesses by country - last 12 months
Accesses by referrer - last 12 months
Impact and interest
Additional statistics for this record are available via IRStats2

Actions (login required)

Edit Item Edit Item