Aedes aegypti Mosquitoes Exhibit Decreased Repellency by DEET following Previous Exposure


Stanczyk, NM; Brookfield, JFY; Field, LM; Logan, JG; (2013) Aedes aegypti Mosquitoes Exhibit Decreased Repellency by DEET following Previous Exposure. PLoS One, 8 (2). ISSN 1932-6203 DOI: https://doi.org/10.1371/journal.pone.0054438

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Abstract

DEET (N,N-Diethyl-m-toluamide) is one of the most widely used mosquito repellents. Although DEET has been shown to be extremely effective, recent studies have revealed that certain individual insects are unaffected by its presence. A genetic basis for this has been shown in Aedes aegypti mosquitoes and the fruit fly Drosophila melanogaster, but, for the triatomine bug, Rhodnius prolixus, a decrease in response to DEET occurred shortly after previous exposure, indicating that non-genetic factors may also be involved in DEET "insensitivity". In this study, we examined host-seeking behaviour and electrophysiological responses of A. aegypti after pre-exposure to DEET. We found that three hours after pre-exposure the mosquitoes showed behavioural insensitivity, and electroantennography revealed this correlated with the olfactory receptor neurons responding less to DEET. The change in behaviour as a result of pre-exposure to DEET has implications for the use of repellents and the ability of mosquitoes to overcome them.

Item Type: Article
Faculty and Department: Faculty of Infectious and Tropical Diseases > Dept of Disease Control
PubMed ID: 23437043
Web of Science ID: 315184200008
URI: http://researchonline.lshtm.ac.uk/id/eprint/856624

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