MAVARIC - a comparison of automation-assisted and manual cervical screening: a randomised controlled trial.


Kitchener, HC; Blanks, R; Cubie, H; Desai, M; Dunn, G; Legood, R; Gray, A; Sadique, Z; Moss, S; MAVARIC Trial Study Group, ; (2011) MAVARIC - a comparison of automation-assisted and manual cervical screening: a randomised controlled trial. Health technology assessment (Winchester, England), 15 (3). iii-iv, ix-xi, 1-170. ISSN 1366-5278 DOI: https://doi.org/10.3310/hta15030

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Abstract

The principal objective was to compare automation-assisted reading of cervical cytology with manual reading using the histological end point of cervical intraepithelial neoplasia grade II (CIN2) or worse (CIN2+). Secondary objectives included (i) an assessment of the slide ranking facility of the Becton Dickinson (BD) FocalPoint™ Slide Profiler (Becton Dickinson, Franklin Lakes, NJ, USA), especially 'No Further Review', (ii) a comparison of the two approved automated systems, the ThinPrep® Imaging System (Hologic, Bedford, MA, USA) and the BD FocalPoint Guided Screener Imaging System, and (iii) automated versus manual in terms of productivity and cost-effectiveness.

Item Type: Article
Faculty and Department: Faculty of Public Health and Policy > Dept of Health Services Research and Policy
PubMed ID: 21266159
URI: http://researchonline.lshtm.ac.uk/id/eprint/843

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