Meclonazepam analogues as potential new antihelmintic agents


Mahajan, A; Kumar, V; Mansour, NRN; Bickle, Q; Chibale, K; (2008) Meclonazepam analogues as potential new antihelmintic agents. Bioorganic & medicinal chemistry letters, 18 (7). pp. 2333-2336. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2008.02.077

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Abstract

New analogues of the potent antihelmintic meclonazepam were prepared and evaluated against Schistosoma mansoni. The biological data suggests substitution at positions 2 and 4 of meclonazepam could provide promising analogues for prophylactic and therapeutic activity against S. mansoni. (C) 2008 Elsevier Ltd. All rights reserved.

Item Type: Article
Keywords: meclonazepam, Schistosomiasis, SCHISTOSOMA-MANSONI, PRAZIQUANTEL, OXAMNIQUINE
Faculty and Department: Faculty of Infectious and Tropical Diseases > Dept of Immunology and Infection
PubMed ID: 18343662
Web of Science ID: 255246300019
URI: http://researchonline.lshtm.ac.uk/id/eprint/7544

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