Exposure to indoor mould and children's respiratory health in the PATY study


Antova, T; Pattenden, S; Brunekreef, B; Heinrich, J; Rudnai, P; Forastiere, F; Luttmann-Gibson, H; Grize, L; Katsnelson, B; Moshammer, H; Nikiforov, B; Slachtova, H; Slotova, K; Zlotkowska, R; Fletcher, T; (2008) Exposure to indoor mould and children's respiratory health in the PATY study. Journal of epidemiology and community health, 62 (8). pp. 708-714. ISSN 0143-005X DOI: https://doi.org/10.1136/jech.2007.065896

Full text not available from this repository. (Request a copy)

Abstract

BACKGROUND: Living in a damp or mouldy home reportedly damages children's respiratory health, yet mould appears not to be a prominent risk factor in the public's perception. Analyses of data on over 58,000 children from the Pollution and the Young (PATY) study are presented. In this collaboration, researchers from 12 cross-sectional studies pooled their data to assess the effects of air quality on a spectrum of children's respiratory disorders. METHOD: Original studies were conducted in Russia, North America and 10 countries in Eastern and Western Europe. Pooled analyses were restricted to children aged 6-12 years. Associations between visible mould reported in the household and a spectrum of eight respiratory and allergic symptoms were estimated within each study. Logistic regressions were used, controlling for individual risk factors and for study area. Heterogeneity between study-specific results and mean effects (allowing for heterogeneity) were estimated using meta-analysis. RESULTS: Visible mould was reported by 13.9% of respondents in Russia, increasing to 39.1% in North America. Positive associations between exposure to mould and children's respiratory health were seen with considerable consistency across studies and across outcomes. Confounder-adjusted combined ORs ranged from 1.30 (95% CI 1.22 to 1.39) for "nocturnal cough" to 1.50 (1.31 to 1.73) for "morning cough". Evidence of stronger effects in more crowded households was statistically significant for only asthma and sensitivity to inhaled allergens. No consistent interactions between mould and age, sex or parental smoking were found. CONCLUSION: Indoor mould exposure was consistently associated with adverse respiratory health outcomes in children living in these diverse countries.

Item Type: Article
Faculty and Department: Faculty of Public Health and Policy > Dept of Social and Environmental Health Research
Research Centre: Centre for Maternal, Reproductive and Child Health (MARCH)
PubMed ID: 18621956
Web of Science ID: 257556400009
URI: http://researchonline.lshtm.ac.uk/id/eprint/7254

Statistics


Download activity - last 12 months
Downloads since deposit
0Downloads
303Hits
Accesses by country - last 12 months
Accesses by referrer - last 12 months
Impact and interest
Additional statistics for this record are available via IRStats2

Actions (login required)

Edit Item Edit Item