Contact tracing and disease control


Eames, KTD; Keeling, MJ; (2003) Contact tracing and disease control. Proceedings Biological sciences / The Royal Society, 270 (1533). pp. 2565-2571. ISSN 0962-8452 DOI: https://doi.org/10.1098/rspb.2003.2554

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Abstract

Contact tracing, followed by treatment or isolation, is a key control measure in the battle against infectious diseases. It is an extreme form of locally targeted control, and as such has the potential to be highly efficient when dealing with low numbers of cases. For this reason it is frequently used to combat sexually transmitted diseases and new invading pathogens. Accurate modelling of contact tracing requires explicit information about the disease-transmission pathways from each individual, and hence the network of contacts. Here, pairwise-approximation methods and full stochastic simulations are used to investigate the utility of contact tracing. A simple relationship is found between the efficiency of contact tracing necessary for eradication and the basic reproductive ratio of the disease. This holds for a wide variety of realistic situations including heterogeneous networks containing core-groups or super-spreaders, and asymptomatic individuals. Clustering (transitivity) within the transmission network is found to destroy the relationship, requiring lower efficiency than predicted.

Item Type: Article
Keywords: Communicable Disease Control, methods, Computer Simulation, Contact Tracing, Disease Transmission, Horizontal, Humans, Models, Biological, Sexually Transmitted Diseases, transmission, Stochastic Processes
Faculty and Department: Faculty of Epidemiology and Population Health > Dept of Infectious Disease Epidemiology
PubMed ID: 14728778
Web of Science ID: 187989900005
URI: http://researchonline.lshtm.ac.uk/id/eprint/6928

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