Economic evaluation of vaccination programs: the impact of herd-immunity
Brisson, M; Edmunds, WJ; (2003) Economic evaluation of vaccination programs: the impact of herd-immunity. Medical decision making , 23 (1). pp. 76-82. ISSN 0272-989XFull text not available from this repository.
The unique characteristic of vaccination is that it not only reduces the incidence of disease in those immunized but also indirectly protects nonvaccinated susceptibles against infection (produces herd-immunity). The bulk of economic evaluations of vaccination programs continue to use models that cannot take into account the indirect effects produced by herd-immunity. Here, the authors illustrate the importance of incorporating herd-immunity externalities when assessing the cost-effectiveness of vaccination progams. To do this, they compare 2 methods of estimating the benefits of routine mass vaccination: one that includes herd-immunity (dynamic approach) and one that does not (static approach). Finally, they use the results to clarify a number of misconceptions that are common in the literature concerning herd-immunity and dynamical effects produced by models.
|Keywords:||Adolescent, Adult, Age Factors, Aged, Chickenpox/epidemiology/prevention & control/transmission, Child, Child, Preschool, Computer Simulation, Cost-Benefit Analysis/*statistics & numerical data, England/epidemiology, Humans, *Immunity, Herd, Incidence, Infant, Infant, Newborn, Mass Immunization/*economics, Middle Aged, *Models, Statistical, Wales/epidemiology, Adolescent, Adult, Age Factors, Aged, Chickenpox, epidemiology, prevention & control, transmission, Child, Child, Preschool, Computer Simulation, Cost-Benefit Analysis, statistics & numerical data, England, epidemiology, Humans, Immunity, Herd, Incidence, Infant, Infant, Newborn, Mass Immunization, economics, Middle Aged, Models, Statistical, Wales, epidemiology|
|Faculty and Department:||Faculty of Epidemiology and Population Health > Dept of Infectious Disease Epidemiology|
|Web of Science ID:||180665300007|
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