Tools for molecular epidemiology of leishmaniasis


Mauricio, I; (2004) Tools for molecular epidemiology of leishmaniasis. [Conference or Workshop Item]

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Abstract

Molecular biology provides a range of tools for epidemiological investigations. So far, there has been limited application of molecular epidemiology in leishmaniasis research. The type of questions that can be addressed may be geographical or populational, may relate to the life cycle and to the disease caused. PCR-RFLPs, DNA sequencing and microsatellites have been applied. No single method has an adequate combination of discriminatory power, reproducibility and simplicity to be applied to all questions and their use will be discussed. The availability of the genome sequences for Leishmania major and Leishmania infantum will give significant impetus to the development of new tools. Multiple user databases will maximise exploitation of the new genetic markers.

Item Type: Conference or Workshop Item
Keywords: DONOVANI COMPLEX, INFANTUM
Faculty and Department: Faculty of Infectious and Tropical Diseases > Dept of Pathogen Molecular Biology
Research Centre: Leishmaniasis Group
Web of Science ID: 235290700009
URI: http://researchonline.lshtm.ac.uk/id/eprint/6420

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