To RCT or not to RCT: deciding when 'more evidence is needed' for public health policy and practice.


Petticrew, M; Chalabi, Z; Jones, DR; (2012) To RCT or not to RCT: deciding when 'more evidence is needed' for public health policy and practice. Journal of epidemiology and community health, 66 (5). pp. 391-6. ISSN 0143-005X DOI: https://doi.org/10.1136/jech.2010.116483

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Abstract

BACKGROUND: Amid the calls for 'more public health evidence', we also need simple understandable methods of determining when more research really is needed. This paper describes a simple decision aid to help policymakers, researchers and other decision makers assess the potential 'information value' of a new public health randomised controlled trial.<br/> METHODS: The authors developed a flow chart to help make explicit (1) the user's information needs, (2) the intended use of the new information that the study will produce, (3) the added value of the evidence to be derived from the new study and (4) the levels of precision, bias and generalisability required by the user.<br/> RESULTS: The flow chart is briefly illustrated, first in generic form and then in a worked example, showing how it may be used in deciding whether a new study should be commissioned to evaluate the health impact of allowing motorcycles to use bus lanes in London.<br/> CONCLUSIONS: In this paper, the authors have presented a flow chart for enacting an informal 'Value-of-Information'-like approach to deciding when a new public health evaluation is needed. The authors do not suggest that the flow chart approach is technically the equivalent of Value-of-Information methods. Nonetheless, it represents a valuable perspective and process to adopt, and this structured approach will be more revealing than an unstructured thought experiment as the basis for decisions about a new study. To aid in its development as an effective tool, we invite users from a variety of perspectives and contexts to review it, to use it in practice and to send us their comments.<br/>

Item Type: Article
Faculty and Department: Faculty of Public Health and Policy > Dept of Social and Environmental Health Research
Research Centre: Centre for Global Non-Communicable Diseases (NCDs)
PubMed ID: 21652521
Web of Science ID: 302472400005
URI: http://researchonline.lshtm.ac.uk/id/eprint/634

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