Prospects for improved bluetongue vaccines.


Roy, P; Boyce, M; Noad, R; (2009) Prospects for improved bluetongue vaccines. Nature reviews Microbiology, 7 (2). pp. 120-8. ISSN 1740-1526 DOI: 10.1038/nrmicro2052

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Abstract

Bluetongue has been recognized as a viral disease of livestock for more than 100 years. Repeated incursions of Bluetongue into Europe since 1998 have been particularly devastating for highly sensitive European fine-wool sheep breeds, and have resulted in a resurgence of interest in vaccine manufacture. Fortunately, the virus and its serology are well understood and vaccination prevents the disease. However, current vaccines are not without their problems, and many new approaches are being tested to improve the safety and breadth of protection afforded. This review describes the leading technologies for improved bluetongue vaccines and looks ahead to how advances in other viral vaccines might be applied to this disease.

Item Type: Article
Faculty and Department: Faculty of Infectious and Tropical Diseases > Dept of Pathogen Molecular Biology
Research Centre: Vaccine Centre
PubMed ID: 19148179
Web of Science ID: 263090900011
URI: http://researchonline.lshtm.ac.uk/id/eprint/5938

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