The epidemiology and etiology of Perthes disease.

Perry, DC; Hall, AJ; (2011) The epidemiology and etiology of Perthes disease. The Orthopedic clinics of North America, 42 (3). 279-83, v. ISSN 0030-5898 DOI:

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: The incidence of Perthes disease varies markedly both between countries and within countries down to a local level. The disease is more common in white than in Asian or black African children. The disease is associated with deprivation; with a steep disease gradient across social class groups. This epidemiology alongside the lack of concordance in twins suggests a strong environmental etiology, with little evidence to suggest a genetic predisposition. Children are frequently short, with a growth pattern described as "rostral-sparing". A propensity to associated congenital anomalies suggests an intrauterine cause.

Item Type: Article
Faculty and Department: Faculty of Epidemiology and Population Health > Dept of Infectious Disease Epidemiology
PubMed ID: 21742139
Web of Science ID: 208681000002


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