Tuberculosis infection in zambia: the association with relative wealth.


Boccia, D; Hargreaves, J; Ayles, H; Fielding, K; Simwinga, M; Godfrey-Faussett, P; (2009) Tuberculosis infection in zambia: the association with relative wealth. The American journal of tropical medicine and hygiene, 80 (6). pp. 1004-11. ISSN 0002-9637

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Abstract

: This study aimed to assess the association between household socioeconomic position and tuberculosis (TB) infection in two communities of Zambia. For this purpose we implemented a cross-sectional investigation, nested within a larger case control study. Infection was assessed using Quantiferon-TB Gold. A socioeconomic position index was constructed through principal component analysis combining data on human resources, food availability, housing quality, and access to services and infrastructures. In this study, higher socioeconomic position, rather than lower, was associated with significantly higher risk of TB infection. None of the traditional risk factors for TB infection mediated this association, suggesting that in these two communities TB transmission may occur through exposure to as yet undefined risk factors that are associated with higher socioeconomic position. Although further studies are needed, these results suggest emerging new patterns of TB transmission and a role of socioeconomic position on the risk of TB infection opposite to that expected.<br/>

Item Type: Article
Faculty and Department: Faculty of Infectious and Tropical Diseases > Dept of Clinical Research
Faculty of Epidemiology and Population Health > Dept of Infectious Disease Epidemiology
Faculty of Public Health and Policy > Dept of Social and Environmental Health Research
Faculty of Public Health and Policy > Dept of Global Health and Development
Research Centre: Centre for Evaluation
Malaria Centre
TB Centre
Tropical Epidemiology Group
PubMed ID: 19478266
Web of Science ID: 266645800026
URI: http://researchonline.lshtm.ac.uk/id/eprint/5396

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