Marked increase in child survival after four years of intensive malaria control.


Kleinschmidt, I; Schwabe, C; Benavente, L; Torrez, M; Ridl, FC; Segura, JL; Ehmer, P; Nchama, GN; (2009) Marked increase in child survival after four years of intensive malaria control. The American journal of tropical medicine and hygiene, 80 (6). pp. 882-8. ISSN 0002-9637

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Abstract

: In malaria-endemic countries in Africa, a large proportion of child deaths are directly or indirectly attributable to infection with Plasmodium falciparum. Four years after high coverage, multiple malaria control interventions were introduced on Bioko Island, Equatorial Guinea, changes in infection with malarial parasites, anemia, and fever history in children were estimated and assessed in relation to changes in all-cause under-5 mortality. There were reductions in prevalence of infection (odds ratio [OR] = 0.31, 95% confidence interval [CI] = 0.2-0.46), anemia (OR = 0.11, 95% CI = 0.07-0.18), and reported fevers (OR = 0.41, 95% CI = 0.22-0.76) in children. Under-5 mortality fell from 152 per 1,000 births (95% CI = 122-186) to 55 per 1,000 (95% CI = 38-77; hazard ratio = 0.34 [95% CI = 0.23-0.49]). Effective malaria control measures can dramatically increase child survival and play a key role in achieving millennium development goals.<br/>

Item Type: Article
Faculty and Department: Faculty of Epidemiology and Population Health > Dept of Infectious Disease Epidemiology
Research Centre: Malaria Centre
Tropical Epidemiology Group
PubMed ID: 19478243
Web of Science ID: 266645800003
URI: http://researchonline.lshtm.ac.uk/id/eprint/5395

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