LSHTM Research Online

Greenwood, B; Targett, G; (2009) Do we still need a malaria vaccine? Parasite immunology, 31 (9). pp. 582-6. ISSN 0141-9838 DOI: https://doi.org/10.1111/j.1365-3024.2009.01140.x

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Abstract

An unexpectedly large reduction in the burden of malaria has recently been achieved in a number of malaria endemic countries following the scaling up of effective treatment and simple vector control programmes. These achievements question the need for a partially effective malaria vaccine targeted at disease prevention. If an anti-disease vaccine is to replace or supplement existing control measures a high level of efficacy, sustained over a number of years, will be required. Recent successes in malaria control have re-awakened interest in the possibility of malaria elimination in areas where this was not previously considered to be a feasible objective. Malaria vaccines with transmission-blocking properties could play a key role in future elimination programmes.

Item Type:	Article
Faculty and Department:	Faculty of Infectious and Tropical Diseases > Dept of Disease Control Faculty of Infectious and Tropical Diseases > Dept of Immunology and Infection
Research Centre:	Malaria Centre Vaccine Centre
PubMed ID:	19691561
Web of Science ID:	268760300010
URI:	http://researchonline.lshtm.ac.uk/id/eprint/4945

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