This paper explains a novel approach for knowledge discovery from data generated by Point of Care (POC) devices. A very important element of this type of knowledge extraction is that the POC generated data would never be identifiable, thereby protecting the rights and the anonymity of the individual, whilst still allowing for vital population-level evidence to be obtained. This paper also reveals a real-world implementation of the novel approach in a big data analytics system. Using Internet of Things (IoT) enabled POC devices and the big data analytics system, the data can be collected, stored, and analyzed in batch and real-time modes to provide a detailed picture of a healthcare system as well to identify high-risk populations and their locations. In addition, the system offers benefits to national health authorities in forms of optimized resource allocation (from allocating consumables to finding the best location for new labs) thus supports efficient and timely decision-making processes.