Host genetic studies in human ocular Chlamydial infection.


Natividad-Sancho, A; Holland, MJ; Mabey, DC; Bailey, RL; (2009) Host genetic studies in human ocular Chlamydial infection. Drugs of today (Barcelona, Spain, 45 Suppl B. pp. 61-6. ISSN 1699-3993

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Abstract

Several human and animal models and methods have been used to dissect genetic contributions to immunity and pathogenesis of chlamydial diseases. Considerable achievements have been made in this field of host genetics. The hope is that these studies will lead to medical applications by helping to elicit the function of genes that are involved in host defense against chlamydia and in progression to severe sequelae. In the present article, we review a selection of findings in the forward genetics of ocular Chlamydia trachomatis infection in humans.

Item Type: Article
Faculty and Department: Faculty of Infectious and Tropical Diseases > Dept of Clinical Research
Research Centre: Centre for Maternal, Reproductive and Child Health (MARCH)
Neglected Tropical Diseases Network
PubMed ID: 20011696
Web of Science ID: 272015100010
URI: http://researchonline.lshtm.ac.uk/id/eprint/4248

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