Prevalence and characteristics of asymptomatic norovirus infection in the community in England.


Phillips, G; Tam, CC; Rodrigues, LC; Lopman, B; (2010) Prevalence and characteristics of asymptomatic norovirus infection in the community in England. Epidemiology and infection, 138 (10). pp. 1454-8. ISSN 0950-2688 DOI: 10.1017/S0950268810000439

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Abstract

: Norovirus is a major cause of infectious intestinal disease, and a substantial prevalence of asymptomatic infection has been reported. We describe the prevalence, seasonality and characteristics of asymptomatic norovirus infection in England. Healthy individuals were recruited at random from the general population during the Study of Infectious Intestinal Disease (1993-1996). Norovirus was identified using real-time RT-PCR. The age-adjusted prevalence of asymptomatic norovirus infection was 12%; prevalence was highest in children aged <5 years and showed wintertime seasonality. More work is needed to understand whether asymptomatic infections are important for norovirus transmission leading to sporadic illness and outbreaks.<br/>

Item Type: Article
Faculty and Department: Faculty of Epidemiology and Population Health > Dept of Infectious Disease Epidemiology
Faculty of Public Health and Policy > Dept of Health Services Research and Policy
Research Centre: Centre for Global Non-Communicable Diseases (NCDs)
Vaccine Centre
PubMed ID: 20196905
Web of Science ID: 282195900013
URI: http://researchonline.lshtm.ac.uk/id/eprint/3715

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