Psoriasis and comorbid diseases: Epidemiology.


Takeshita, J; Grewal, S; Langan, SM; Mehta, NN; Ogdie, A; Van Voorhees, AS; Gelfand, JM; (2017) Psoriasis and comorbid diseases: Epidemiology. Journal of the American Academy of Dermatology, 76 (3). pp. 377-390. ISSN 0190-9622 DOI: https://doi.org/10.1016/j.jaad.2016.07.064

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Abstract

Psoriasis is a common chronic inflammatory disease of the skin that is increasingly being recognized as a systemic inflammatory disorder. Psoriatic arthritis is a well-known comorbidity of psoriasis. A rapidly expanding body of literature in various populations and settings supports additional associations between psoriasis and cardiometabolic diseases, gastrointestinal diseases, kidney disease, malignancy, infection, and mood disorders. The pathogenesis of comorbid disease in patients with psoriasis remains unknown; however, shared inflammatory pathways, cellular mediators, genetic susceptibility, and common risk factors are hypothesized to be contributing elements. As additional psoriasis comorbidities continue to emerge, education of health care providers is essential to ensuring comprehensive medical care for patients with psoriasis.

Item Type: Article
Faculty and Department: Faculty of Epidemiology and Population Health > Dept of Non-Communicable Disease Epidemiology
Research Centre: EHR Research Group
PubMed ID: 28212759
Web of Science ID: 399214700010
URI: http://researchonline.lshtm.ac.uk/id/eprint/3515697

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