Spatio-temporal analysis of malaria incidence in the Peruvian Amazon Region between 2002 and 2013.


Soto-Calle, V; Rosas-Aguirre, A; Llanos-Cuentas, A; Abatih, E; DeDeken, R; Rodriguez, H; Rosanas-Urgell, A; Gamboa, D; D'Alessandro, U; Erhart, A; Speybroeck, N; (2017) Spatio-temporal analysis of malaria incidence in the Peruvian Amazon Region between 2002 and 2013. Scientific reports, 7. p. 40350. ISSN 2045-2322 DOI: https://doi.org/10.1038/srep40350

[img]
Preview
Text - Published Version
License:

Download (3MB) | Preview

Abstract

Malaria remains a major public health problem in the Peruvian Amazon where the persistence of high-risk transmission areas (hotspots) challenges the current malaria control strategies. This study aimed at identifying significant space-time clusters of malaria incidence in Loreto region 2002-2013 and to determine significant changes across years in relation to the control measures applied. Poisson regression and purely temporal, spatial, and space-time analyses were conducted. Three significantly different periods in terms of annual incidence rates (AIR) were identified, overlapping respectively with the pre-, during, and post- implementation control activities supported by PAMAFRO project. The most likely space-time clusters of malaria incidence for P. vivax and P. falciparum corresponded to the pre- and first two years of the PAMAFRO project and were situated in the northern districts of Loreto, while secondary clusters were identified in eastern and southern districts with the latest onset and the shortest duration of PAMAFRO interventions. Malaria in Loreto was highly heterogeneous at geographical level and over time. Importantly, the excellent achievements obtained during 5 years of intensified control efforts totally vanished in only 2 to 3 years after the end of the program, calling for sustained political and financial commitment for the success of malaria elimination as ultimate goal.

Item Type: Article
Faculty and Department: Faculty of Infectious and Tropical Diseases > Dept of Disease Control
PubMed ID: 28091560
URI: http://researchonline.lshtm.ac.uk/id/eprint/3364164

Statistics


Download activity - last 12 months
Downloads since deposit
35Downloads
43Hits
Accesses by country - last 12 months
Accesses by referrer - last 12 months
Impact and interest
Additional statistics for this record are available via IRStats2

Actions (login required)

Edit Item Edit Item