Diagnostic Accuracy of a Prototype Point-of-Care Test for Ocular Chlamydia trachomatis under Field Conditions in The Gambia and Senegal.


Harding-Esch, EM; Holland, MJ; Schémann, JF; Molina, S; Sarr, I; Andreasen, AA; Roberts, CH; Sillah, A; Sarr, B; Harding, EF; Edwards, T; Bailey, RL; Mabey, DC; (2011) Diagnostic Accuracy of a Prototype Point-of-Care Test for Ocular Chlamydia trachomatis under Field Conditions in The Gambia and Senegal. PLoS neglected tropical diseases, 5 (8). e1234. ISSN 1935-2727 DOI: 10.1371/journal.pntd.0001234

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Abstract

The clinical signs of active trachoma are often present in the absence of ocular Chlamydia trachomatis infection in low prevalence and mass treated settings. Treatment decisions are currently based on the prevalence of clinical signs, and this may result in the unnecessary distribution of mass antibiotic treatment. We aimed to evaluate the diagnostic accuracy of a prototype point-of-care (POC) test, developed for field diagnosis of ocular C. trachomatis, in low prevalence settings of The Gambia and Senegal.

Item Type: Article
Faculty and Department: Faculty of Infectious and Tropical Diseases > Dept of Clinical Research
Faculty of Epidemiology and Population Health > Dept of Infectious Disease Epidemiology
Research Centre: Neglected Tropical Diseases Network
Tropical Epidemiology Group
PubMed ID: 21829735
Web of Science ID: 294479800006
URI: http://researchonline.lshtm.ac.uk/id/eprint/333

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