Antiretroviral Therapy for Control of the HIV-associated Tuberculosis Epidemic in Resource-Limited Settings


Lawn, SD; Kranzer, K; Wood, R; (2009) Antiretroviral Therapy for Control of the HIV-associated Tuberculosis Epidemic in Resource-Limited Settings. Clinics in chest medicine, 30 (4). 685-+. ISSN 0272-5231 DOI: https://doi.org/10.1016/j.ccm.2009.08.010

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Abstract

Great progress has been made over the past few years in HIV testing in patients who have tuberculosis (TB) and in the scale-up of antiretroviral therapy. More than 3 million people in resource-limited settings were estimated to have started antiretroviral therapy by the end of 2007 and 2 million of these were in sub-Saharan Africa. However, little is known about what impact this massive public health intervention will have on the HIV-associated TB epidemic or how antiretroviral therapy might be used to best effect TB control. This article provides an in-depth review of these issues.

Item Type: Article
Keywords: HIV, Tuberculosis, Antiretroviral, Disease control, Mortality, ISONIAZID PREVENTIVE THERAPY, SUB-SAHARAN AFRICA, RECONSTITUTION, INFLAMMATORY SYNDROME, RIO-DE-JANEIRO, SOUTH-AFRICA, INFECTED PATIENTS, IMMUNE RECONSTITUTION, RISK-FACTORS, RECURRENT TUBERCULOSIS, MYCOBACTERIUM-TUBERCULOSIS, AIDS-Related Opportunistic Infections, epidemiology, prevention & control, Anti-Retroviral Agents, therapeutic use, Humans, Morbidity, Tuberculosis, epidemiology, prevention & control, World Health
Faculty and Department: Faculty of Infectious and Tropical Diseases > Dept of Clinical Research
Faculty of Epidemiology and Population Health > Dept of Infectious Disease Epidemiology
Research Centre: TB Centre
PubMed ID: 19925961
Web of Science ID: 279256200005
URI: http://researchonline.lshtm.ac.uk/id/eprint/3288

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