Tuberculosis research update

Hanekom, WA; Lawn, SD; Dheda, K; Whitelaw, A; (2010) Tuberculosis research update. Tropical medicine & international health, 15 (8). pp. 981-989. ISSN 1360-2276 DOI:

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Tuberculosis (TB) remains a major challenge to global public health in the 21st century. In 2007, there were an estimated 9.27 million new cases and 1.3 million deaths among HIV-negative patients with TB. The HIV-associated TB epidemic, drug-resistant disease, the need for better diagnostic assays and the limited efficacy of Bacille Calmette-Guerin vaccination are four important obstacles to further progress in global TB control. In this brief review, we provide a focused update on these four key areas of TB research.

Item Type: Article
Keywords: tuberculosis, vaccine, drug resistance, HIV, diagnosis, MULTIDRUG-RESISTANT TUBERCULOSIS, RECONSTITUTION INFLAMMATORY SYNDROME, ACTIVE ANTIRETROVIRAL THERAPY, RESOURCE-LIMITED SETTINGS, CALMETTE-GUERIN VACCINE, ACID-FAST BACILLI, MYCOBACTERIUM-TUBERCULOSIS, IMMUNE RECONSTITUTION, SOUTH-AFRICA, MICROSCOPIC-OBSERVATION, AIDS-Related Opportunistic Infections, therapy, Anti-HIV Agents, therapeutic use, Humans, Tuberculosis, diagnosis, epidemiology, therapy, Tuberculosis Vaccines, Tuberculosis, Multidrug-Resistant, diagnosis, therapy
Faculty and Department: Faculty of Infectious and Tropical Diseases > Dept of Clinical Research
PubMed ID: 20561306
Web of Science ID: 279939900134


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