Identification of a 1,2,4,5-tetraoxane antimalarial drug-development candidate (RKA 182) with superior properties to the semisynthetic artemisinins.

O'Neill, Paul M; Amewu, Richard K; Nixon, Gemma L; Bousejra ElGarah, Fatima; Mungthin, Mathirut; Chadwick, James; Shone, Alison E; Vivas, Livia; Lander, Hollie; Barton, Victoria; +9 more... Muangnoicharoen, Sant; Bray, Patrick G; Davies, Jill; Park, B Kevin; Wittlin, Sergio; Brun, Reto; Preschel, Michael; Zhang, Kesheng; Ward, Stephen A; (2010) Identification of a 1,2,4,5-tetraoxane antimalarial drug-development candidate (RKA 182) with superior properties to the semisynthetic artemisinins. Angewandte Chemie (International ed in English), 49 (33). pp. 5693-5697. ISSN 1433-7851 DOI: https://doi.org/10.1002/anie.201001026

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