Drug-resistant tuberculosis transmission and resistance amplification within families.


Seddon, JA; Warren, RM; Enarson, DA; Beyers, N; Schaaf, HS; (2012) Drug-resistant tuberculosis transmission and resistance amplification within families. Emerging infectious diseases, 18 (8). pp. 1342-5. ISSN 1080-6040 DOI: https://doi.org/10.3201/eid1808.111650

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Abstract

: Drug-resistant tuberculosis is caused by transmission of resistant strains of Mycobacterium tuberculosis and by acquisition of resistance through inadequate treatment. We investigated the clinical and molecular features of the disease in 2 families after drug-resistant tuberculosis was identified in 2 children. The findings demonstrate the potential for resistance to be transmitted and amplified within families.

Item Type: Article
Faculty and Department: Faculty of Infectious and Tropical Diseases > Dept of Clinical Research
PubMed ID: 22840848
Web of Science ID: 307209800021
URI: http://researchonline.lshtm.ac.uk/id/eprint/296508

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