HLA-DRB1*11 and variants of the MHC class II locus are strong risk factors for systemic juvenile idiopathic arthritis.

Ombrello, MJ; Remmers, EF; Tachmazidou, I; Grom, A; Foell, D; Haas, JP; Martini, A; Gattorno, M; Özen, S; Prahalad, S; +257 more... Zeft, AS; Bohnsack, JF; Mellins, ED; Ilowite, NT; Russo, R; Len, C; Hilario, MO; Oliveira, S; Yeung, RS; Rosenberg, A; Wedderburn, LR; Anton, J; Schwarz, T; Hinks, A; Bilginer, Y; Park, J; Cobb, J; Satorius, CL; Han, B; Baskin, E; Signa, S; Duerr, RH; Achkar, JP; Kamboh, MI; Kaufman, KM; Kottyan, LC; Pinto, D; Scherer, SW; Alarcón-Riquelme, ME; Docampo, E; Estivill, X; Gül, A; British Society of Pediatric and Adolescent Rheumatology (BSPAR); Childhood Arthritis Prospective Study (CAPS) Group; Randomized Placebo Phase Study of Rilonacept in sJIA (RAPPORT) I; Sparks-Childhood Arthritis Response to Medication Study (CHARMS); Biologically Based Outcome Predictors in JIA (BBOP) Group; de Bakker, PI; Raychaudhuri, S; Langefeld, CD; Thompson, S; Zeggini, E; Thomson, W; Kastner, DL; Woo, P; International Childhood Arthritis Genetics (INCHARGE) Consortium; , COLLABORATORS; Achkar, JP; Alarcón-Riquelme, ME; Allen, R; Anton, J; Baskin, E; Berg, S; Bica, B; Bilginer, Y; Bohnsack, JF; Cavalcanti, A; Chaitow, J; Cobb, J; Cuttica, R; de Bakker, PI; Docampo, E; Duerr, R; Ellis, J; Estivill, X; Finkel, TH; Foell, D; Gattorno, M; Grom, A; Gül, A; Haas, JP; Hakonarson, H; Han, B; Hilario, MO; Hinks, A; Ilowite, NT; Kamboh, MI; Kastner, DL; Kaufman, K; Kottyan, LC; Langefeld, C; Len, C; Martini, A; Mellins, ED; Minden, K; Murray, K; Oliveira, S; Ombrello, MJ; Ozen, S; Park, J; Pinto, D; Prahalad, S; Quartier, P; Raychaudhuri, S; Remmers, EF; Rosenberg, A; Russo, R; Satorius, C; Scherer, SW; Schneider, R; Schwarz, T; Singh-Gerwal, D; Tachmazidou, I; Thompson, S; Thomson, W; Wedderburn, LR; Woo, P; Wulffraat, N; Yeung, RS; Zeft, AS; Zeggini, E; Abinum, M; Bell, A; Craft, AW; Crawley, E; David, J; Foster, H; Gardener-Medwin, J; Griffin, J; Hall, A; Hall, M; Herrick, AL; Hollingworth, P; Holt, L; Jones, S; Pountain, G; Ryder, C; Southwood, T; Stewart, I; Venning, H; Wedderburn, LR; Woo, P; Wyatt, S; Baildam, E; Bishop, N; Brown, L; Buckley, J; Chieng, A; Carrasco, R; Cobb, J; Cook, L; Davidson, J; Duggan, A; Eltringham, M; Foster, H; Friel, E; Friswell, M; Gardner-Medwin, J; Gilbert, P; Gould, V; Hadfield, K; Hyrich, K; Jones, J; Lal, S; Lay, M; Lloyd, G; Lloyd, O; Lydon, C; Makengo, N; McGovern, A; Meijer, A; Mills-Wierda, N; Moorcroft, T; Price, V; Qiao, L; Riding, K; Sim, J; Southwood, T; Thomson, W; Todd, M; Tremble, S; Venter, K; Wade, D; Ward, P; Watson, S; Webster, G; Wedderburn, LR; Zelenovic, J; Birmingham, JD; Elder, M; Gottlieb, BS; Ilowite, NT; Imundo, LF; Kimura, Y; Lokhnygina, Y; Miller, ML; Milojevic, D; O'Neil, K; Punaro, MG; Prather, K; Ruth, NM; Sandborg, CI; Schanberg, LE; Sherry, DD; Singer, NG; Spalding, SJ; Tarvin, SE; Verbsky, JW; Wallace, CA; Zemel, LS; Burkle, K; Cobb, J; Etheridge, A; Gilbert, P; Hinks, A; Hirani, S; Kassoumeri, L; Lal, S; Melville, L; Moncrieffe, H; Mulligan, K; Newman, S; Patrick, F; Southwood, T; Thomson, W; Ursu, S; Wedderburn, LR; Whitworth, P; Woo, P; Baxter-Jones, A; Benseler, S; Boire, G; Cabral, DA; Cameron, B; Campillo, S; Chedeville, G; Chetaille, AL; Dancey, P; Duffy, C; Duffy, KW; Ellsworth, J; Feldman, B; Gibbon, M; Guillet, C; Guzman, J; Houghton, K; Huber, A; Jurencak, R; Lang, B; Laxer, R; Maenz, L; Matheson, L; Oen, K; Petty, R; Ramsey, S; Rezaei, E; Rosenberg, A; Roth, J; Schneider, R; Scuccimarri, R; Silverman, E; Spiegel, L; Stringer, E; Tse, S; Tucker, LB; Turvey, S; Yeung, RS; (2015) HLA-DRB1*11 and variants of the MHC class II locus are strong risk factors for systemic juvenile idiopathic arthritis. Proceedings of the National Academy of Sciences of the United States of America, 112 (52). pp. 15970-5. ISSN 0027-8424 DOI: https://doi.org/10.1073/pnas.1520779112

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