Biomonitoring of environmental estrogens in human tissues


Fernandez, MF; Molina-Molina, JM; Lopez-Espinosa, MJ; Freire, C; Campoy, C; Ibarluzea, J; Torne, P; Pedraza, V; Olea, N; (2007) Biomonitoring of environmental estrogens in human tissues. International journal of hygiene and environmental health, 210 (3-4). pp. 429-32. ISSN 1438-4639 DOI: https://doi.org/10.1016/j.ijheh.2007.01.014

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Abstract

Two examples are presented for the application of the total effective xenoestrogen burden as biomarker of chemical exposure measured in tissue samples from patients recruited for two case-control studies. The first study focused on environmental chemicals with hormone mimicking activity, the so-called environmental estrogens, and their participation in the etiology of breast cancer. The second study investigated mother-child exposure to persistent organochlorine chemicals and assessed their combined effect on the risk of male urogenital malformations in the newborn.

Item Type: Article
Keywords: Adipose Tissue/ chemistry, Adult, Aged, Biological Markers, Breast Neoplasms/epidemiology, Case-Control Studies, Environmental Exposure/adverse effects, Environmental Monitoring/ methods, Estrogens/ analysis, Female, Health Surveys, Humans, Hydrocarbons, Chlorinated/analysis, Infant, Newborn, Male, Maternal Exposure, Middle Aged, Pesticides/analysis, Placenta/chemistry, Pregnancy, Prenatal Exposure Delayed Effects, Spain, Urogenital Abnormalities/ epidemiology, Xenobiotics/ analysis, Adipose Tissue, chemistry, Adult, Aged, Biological Markers, Breast Neoplasms, epidemiology, Case-Control Studies, Environmental Exposure, adverse effects, Environmental Monitoring, methods, Estrogens, analysis, Female, Health Surveys, Humans, Hydrocarbons, Chlorinated, analysis, Infant, Newborn, Male, Maternal Exposure, Middle Aged, Pesticides, analysis, Placenta, chemistry, Pregnancy, Prenatal Exposure Delayed Effects, Spain, Urogenital Abnormalities, epidemiology, Xenobiotics, analysis
Faculty and Department: Faculty of Public Health and Policy > Dept of Social and Environmental Health Research
PubMed ID: 17296326
Web of Science ID: 246907000029
URI: http://researchonline.lshtm.ac.uk/id/eprint/2685

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