Marks, M; Mitjà, O; Solomon, AW; Asiedu, KB; Mabey, DC; (2014) Yaws. British medical bulletin, 113. pp. 91-100. ISSN 0007-1420 DOI: https://doi.org/10.1093/bmb/ldu037

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INTRODUCTION: Yaws, caused by Treponema pallidum ssp. pertenue, is endemic in parts of West Africa, Southeast Asia and the Pacific. The WHO has launched a campaign based on mass treatment with azithromycin, to eradicate yaws by 2020.<br/> SOURCES OF DATA: We reviewed published data, surveillance data and data presented at yaws eradication meetings.<br/> AREAS OF AGREEMENT: Azithromycin is now the preferred agent for treating yaws. Point-of-care tests have demonstrated their value in yaws.<br/> AREAS OF CONTROVERSY: There is limited data from 76 countries, which previously reported yaws. Different doses of azithromycin are used in community mass treatment for yaws and trachoma.<br/> GROWING POINTS: Yaws eradication appears an achievable goal. The programme will require considerable support from partners across health and development sectors.<br/> AREAS TIMELY FOR DEVELOPING RESEARCH: Studies to complete baseline mapping, integrate diagnostic tests into surveillance and assess the impact of community mass treatment with azithromycin are ongoing.<br/>

Item Type: Article
Faculty and Department: Faculty of Infectious and Tropical Diseases > Dept of Clinical Research
Research Centre: Neglected Tropical Diseases Network
PubMed ID: 25525120
Web of Science ID: 351512300009
URI: http://researchonline.lshtm.ac.uk/id/eprint/2551629


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