We visit a region of South Africa where HIV is a risk for many living in the population, but particularly Adolescents girls. We hear from a youth group trying to tackle the problem through greater awareness and insight among those affected and Professor Charlotte Watts from the London School of Hygiene and Tropical Medicine explains why adolescent girls are at greater risk of the infection and how her team are developing interventions to reduce this risk. Image: © 2012 Benjamin Soro, Courtesy of Photoshare