An Outbreak of Bartonella bacilliformis in an Endemic Andean Community.


Sanchez Clemente, N; Ugarte-Gil, C; Solorzano, N; Maguiña, C; Moore, D; (2016) An Outbreak of Bartonella bacilliformis in an Endemic Andean Community. PloS one, 11 (3). e0150525. ISSN 1932-6203 DOI: https://doi.org/10.1371/journal.pone.0150525

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Abstract

Bartonellosis affects small Andean communities in Peru, Colombia and Ecuador. Research in this area has been limited. Retrospective review of 191 cases of bartonellosis managed in Caraz District Hospital, Peru, during the last outbreak (2003). The majority of cases (65%) were 14 years old and younger. There was a peak in acute cases after the rainy season; chronic cases presented more constantly throughout the year. The sensitivity of blood smear against blood culture in acute disease was 25%. The most commonly used treatment for chronic disease was rifampicin; chloramphenicol was used to treat most acute cases. Complications arose in 6.8% and there were no deaths. Diagnostic and treatment algorithms for acute and chronic bartonellosis have been developed without a strong evidence base. Preparation of ready-to-go operational research protocols for future outbreaks would strengthen the evidence base for diagnostic and treatment strategies and enhance opportunities for control.

Item Type: Article
Faculty and Department: Faculty of Infectious and Tropical Diseases > Dept of Clinical Research
Research Centre: TB Centre
PubMed ID: 26991495
Web of Science ID: 372582800035
URI: http://researchonline.lshtm.ac.uk/id/eprint/2535622

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