Genomic approaches for understanding dengue: insights from the virus, vector, and host.


Sim, S; Hibberd, ML; (2016) Genomic approaches for understanding dengue: insights from the virus, vector, and host. Genome Biol, 17 (1). p. 38. ISSN 1474-760X DOI: https://doi.org/10.1186/s13059-016-0907-2

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Abstract

The incidence and geographic range of dengue have increased dramatically in recent decades. Climate change, rapid urbanization and increased global travel have facilitated the spread of both efficient mosquito vectors and the four dengue virus serotypes between population centers. At the same time, significant advances in genomics approaches have provided insights into host-pathogen interactions, immunogenetics, and viral evolution in both humans and mosquitoes. Here, we review these advances and the innovative treatment and control strategies that they are inspiring.

Item Type: Article
Faculty and Department: Faculty of Infectious and Tropical Diseases > Dept of Pathogen Molecular Biology
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PubMed ID: 26931545
Web of Science ID: 371275900001
URI: http://researchonline.lshtm.ac.uk/id/eprint/2534262

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