Lipid-Based Nutrient Supplements Increase Energy and Macronutrient Intakes from Complementary Food among Malawian Infants


Hemsworth, J; Kumwenda, C; Arimond, M; Maleta, K; Phuka, J; Rehman, AM; Vosti, SA; Ashorn, U; Filteau, S; Dewey, KG; Ashorn, P; Ferguson, EL; (2016) Lipid-Based Nutrient Supplements Increase Energy and Macronutrient Intakes from Complementary Food among Malawian Infants. The Journal of nutrition, 146 (2). pp. 326-334. ISSN 0022-3166 DOI: https://doi.org/10.3945/jn.115.215327

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Abstract

Background: Low intakes of good-quality complementary foods (CFs) contribute to undernutrition and consequently negatively affect health, growth, and development. Lipid -based nutrient supplements (LNSs) are designed to ensure dietary adequacy in micronutrients and essential fatty acids and to provide some energy and high-quality protein. In populations in which acute energy deficiency is rare, the dose-dependent effect of LNSs on CF intakes is unknown. Objective: The objective of this study was to evaluate the difference in energy and macronutrient intakes from CF between a control (no supplement) group and 3 groups that received 10, 20, or 40 g LNS/d. Methods: We collected repeated interactive 24-h dietary recalls from caregivers of rural Malawian 9- to 10-mo-old infants (n = 748) to estimate dietary intakes (LNS and all non breast-milk foods) of energy and macronutrients and their dietary patterns. All infants were participating in a 12-mo randomized controlled trial to investigate the efficacy of various doses of LNS for preventing undernutrition. Results: Dietary energy intakes were significantly higher among infants in the LNS intervention groups than in the control group (396, 406, and 388 kcal/d in the 10-, 20-, and 40-g LNS/d groups, respectively, compared with 345 kcal/d; each pairwise P< 0.05), but no significant differences were found in energy intakes between groups who were administered the different LNS doses (10 g LNS/d compared with 20 g LNS/d: P= 0.72; 10 g LNS/d compared with 40 g LNS/d: 0.67; 20 g LNS/d compared with 40 g LNS/d: P= 0.94). Intakes of protein and fat were significantly higher in the LNS intervention groups than in the control group. No significant intergroup differences were found in median intakes of energy from non-LNS CFs (357, 347, and 296 kcal/d in the 10-, 20-, and 40-g LNS/d groups, respectively, compared with 345 kcal/d in the control group; P = 0.11). Conclusion: LNSs in doses of 10-40 g/d increase intakes of energy and macronutrients among 9 -to 10-mo-old Malawian infants, without displacing locally available CFs. This trial was registered at clinicaltrials.gov as NCT00945698.

Item Type: Article
Keywords: undernutrition, infants, dietary assessment, lipid-based nutrient, supplement, complementary foods, BREAST-MILK INTAKE, CHILD UNDERNUTRITION, FEEDING PRACTICES, ADEQUACY, GROWTH, BANGLADESH, DIVERSITY, DENSITY, QUALITY, WOMEN
Faculty and Department: Faculty of Epidemiology and Population Health > Dept of Population Health (2012- ) > Dept of Nutrition and Public Health Interventions Research (2003-2012)
Faculty of Epidemiology and Population Health > Dept of Population Health (2012- )
Faculty of Epidemiology and Population Health > Dept of Infectious Disease Epidemiology
Research Centre: Centre for Maternal, Reproductive and Child Health (MARCH)
PubMed ID: 26740684
Web of Science ID: 369557800019
URI: http://researchonline.lshtm.ac.uk/id/eprint/2534024

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