Screening of immigrants in the UK for latent tuberculosis.


McNerney, R; Ferrara, G; O'Grady, J; Maeurer, M; Zumla, A; (2011) Screening of immigrants in the UK for latent tuberculosis. Expert review of respiratory medicine, 5 (4). pp. 483-6. ISSN 1747-6348 DOI: https://doi.org/10.1586/ers.11.45

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Abstract

Evaluation of: Pareek M, Watson JP, Ormerod LP et al. Screening of immigrants in the UK for imported latent tuberculosis: a multicentre cohort study and cost-effectiveness analysis. Lancet Infect. Dis. 11(6), 435-444 (2011). Tuberculosis (TB) is a serious public health problem in the UK, and detection and prophylactic treatment of latent infection offers improved control. A recent study advocates the use of IFN-? release assays to detect latent TB infection in immigrants to the UK under 35 years of age and suggests that such a program would be most cost effective if targeted at new entrants from high burden countries. We discuss these findings in the light of recently updated UK and European guidelines. We conclude that while action to contain TB in the UK is urgently needed, further evidence is required to assess the impact and cost-effectiveness of screening algorithms for latent infection.

Item Type: Article
Faculty and Department: Faculty of Infectious and Tropical Diseases > Dept of Clinical Research
Research Centre: TB Centre
PubMed ID: 21859267
Web of Science ID: 312508200010
URI: http://researchonline.lshtm.ac.uk/id/eprint/251

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