School life expectancy and risk for tuberculosis in Europe.


Machiyama, K; Semenza, JC; Silverwood, RJ; Palmer, MJ; Lim, TA; Manissero, D; Sandgren, A; Ploubidis, GB; (2015) School life expectancy and risk for tuberculosis in Europe. International journal of public health, 61 (5). pp. 603-11. ISSN 1661-8556 DOI: https://doi.org/10.1007/s00038-015-0768-6

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Abstract

OBJECTIVE: This study aims to investigate the effect of country-level school life expectancy on Tuberculosis (TB) incidence to gain further understanding of substantial variation in TB incidence across Europe.<br/> METHODS: An ecological study examined the prospective association between baseline country-level education in 2000 measured by school life expectancy and TB incidence in 2000-2010 in 40 countries of the WHO European region using quantile regression. Subsequently, to validate the ecological associations between education and TB incidence, an individual-level analysis was performed using case-based data in 29 EU/EEA countries from the European Surveillance System (TESSy) and simulating a theoretical control group.<br/> RESULTS: The ecological analysis showed that baseline school life expectancy had a negative prospective association with TB incidence. We observed consistent negative effects of school life expectancy on individuals' TB infections prospectively.<br/> CONCLUSIONS: These findings suggests that country-level education is an important determinant of individual-level TB infection in the region, and in the absence of a social determinants indicator that is routinely collected for reportable infectious diseases, the adoption of country-level education for reportable infectious diseases would significantly advance the field.<br/>

Item Type: Article
Faculty and Department: Faculty of Epidemiology and Population Health > Dept of Medical Statistics
Faculty of Epidemiology and Population Health > Dept of Population Health (2012- ) > Dept of Population Studies (1974-2012)
Faculty of Epidemiology and Population Health > Dept of Population Health (2012- )
Research Centre: Population Studies Group
Centre for Maternal, Reproductive and Child Health (MARCH)
Maternal Health Group
TB Centre
PubMed ID: 26650454
URI: http://researchonline.lshtm.ac.uk/id/eprint/2391565

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